DEJKMDR: miRNA-disease association prediction method based on graph convolutional network.

Numerous studies have shown that miRNAs play a crucial role in the investigation of complex human diseases. Identifying the connection between miRNAs and diseases is crucial for advancing the treatment of complex diseases. However, traditional methods are frequently constrained by the small sample size and high cost, so computational simulations are urgently required to rapidly and accurately forecast the potential correlation between miRNA and disease.

NGCICM: A Novel Deep Learning-Based Method for Predicting circRNA-miRNA Interactions.

The circRNAs and miRNAs play an important role in the development of human diseases, and they can be widely used as biomarkers of diseases for disease diagnosis. In particular, circRNAs can act as sponge adsorbers for miRNAs and act together in certain diseases. However, the associations between the vast majority of circRNAs and diseases and between miRNAs and diseases remain unclear.

SVMMDR: Prediction of miRNAs-drug resistance using support vector machines based on heterogeneous network.

In recent years, the miRNA is considered as a potential high-value therapeutic target because of its complex and delicate mechanism of gene regulation. The abnormal expression of miRNA can cause drug resistance, affecting the therapeutic effect of the disease. Revealing the associations between miRNAs-drug resistance can help in the design of effective drugs or possible drug combinations.

GCNPCA: miRNA-Disease Associations Prediction Algorithm Based on Graph Convolutional Neural Networks.

A growing number of studies have confirmed the important role of microRNAs (miRNAs) in human diseases and the aberrant expression of miRNAs affects the onset and progression of human diseases. The discovery of disease-associated miRNAs as new biomarkers promote the progress of disease pathology and clinical medicine. However, only a small proportion of miRNA-disease correlations have been validated by biological experiments.

GBDTLRL2D Predicts LncRNA-Disease Associations Using MetaGraph2Vec and K-Means Based on Heterogeneous Network.

In recent years, the long noncoding RNA (lncRNA) has been shown to be involved in many disease processes. The prediction of the lncRNA-disease association is helpful to clarify the mechanism of disease occurrence and bring some new methods of disease prevention and treatment. The current methods for predicting the potential lncRNA-disease association seldom consider the heterogeneous networks with complex node paths, and these methods have the problem of unbalanced positive and negative samples.

CRPGCN: predicting circRNA-disease associations using graph convolutional network based on heterogeneous network.

Background: The existing studies show that circRNAs can be used as a biomarker of diseases and play a prominent role in the treatment and diagnosis of diseases. However, the relationships between the vast majority of circRNAs and diseases are still unclear, and more experiments are needed to study the mechanism of circRNAs. Nowadays, some scholars use the attributes between circRNAs and diseases to study and predict their associations.

MSCNE:Predict miRNA-Disease Associations Using Neural Network Based on Multi-Source Biological Information.

The important role of microRNA (miRNA) in human diseases has been confirmed by some studies. However, only using biological experiments has greater blindness, leading to higher experimental costs. In this paper a high-efficiency algorithm based on a variety of biological source information and applying a combination of a convolutional neural network (CNN) feature extractor and an extreme learning machine (ELM) classifier is proposed.

GBDTL2E: Predicting lncRNA-EF Associations Using Diffusion and HeteSim Features Based on a Heterogeneous Network.

Interactions between genetic factors and environmental factors (EFs) play an important role in many diseases. Many diseases result from the interaction between genetics and EFs. The long non-coding RNA (lncRNA) is an important non-coding RNA that regulates life processes.