Given a set of standard binary patterns and a defective pattern, the binary pattern retrieval task is to find the closest pattern to the defective one among these standard patterns. The associative-memory network of Kuramoto oscillators consisting of a Hebbian coupling term and a second-order Fourier term can be applied to this task. When the memorized patterns stored in the Hebbian coupling are mutually orthogonal, recent studies show that the network is capable of distinguishing the memorized patterns from most other patterns.
View Article and Find Full Text PDFNecroptosis is a programmed form of non-apoptotic cell death that requires receptor-interacting protein 3 (RIP3). RIP3 has been shown to be relevant in multiple tumor types and has differential impact on tumor progression. We investigated whether RIP3 is involved in the progression of colitis-associated cancer (CAC) in mice.
View Article and Find Full Text PDFReceptor-interacting protein kinase 3 (RIP3) is the core regulator that switches cell death from apoptosis to necrosis. However, its role in tumor immunity is unknown. In this study, decreased RIP3 expression was observed in patients with hepatocellular carcinoma (HCC), which correlates with myeloid-derived suppressor cell (MDSC) accumulation.
View Article and Find Full Text PDFBlockade of the immunosuppressive checkpoint receptors cytotoxic T-lymphocyte-associated protein 4 (CTLA4) or programmed death 1 (PD-1) and its cognate ligand, programmed death 1 ligand (PD-L1), has altered the landscape of anti-tumor immunotherapy. B7 family and tumor necrosis factor receptor (TNFR) superfamily play a crucial role in T cell activation, tolerance, and anergy through co-stimulatory and inhibitory signal transduction. Investigating the immune molecular landscapes of the B7 and TNFR families is critical in defining the promising responsive candidates.
View Article and Find Full Text PDFWe study a dynamic interplay between Hamiltonian mean-field oscillators and inertial Kuramoto oscillators. We present several sufficient frameworks leading to asymptotic complete synchronization for the mixed ensemble. For a two-oscillator system with the same natural frequencies, we prove that the mixed ensemble exhibits asymptotic complete synchronization for any initial data, whereas we also show that the two-oscillator system tends to asymptotic complete synchronization under an assumption on the uniform boundedness on the phase diameter.
View Article and Find Full Text PDFThis paper mainly studies synchronization between two coupled networks, which is called "outer synchronization." On the basis of Lyapunov function approach, we prove that for networks with balanced structure topology, outer synchronization can be asymptotically reached by using arbitrary coupling strength. We employ a concept which arises in studying the average-consensus problem.
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