Publications by authors named "Zhuang Wen"

Background: The ZJU index is an innovative computational method which integrates BMI, FBG, TG, and ALT to AST ratio. It strongly correlates with measures of lipid metabolism and glucose intolerance. No researches have yet explored the relationship between the ZJU index and sarcopenia.

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  • Researchers are exploring the role of stromal cells, such as fibroblasts, vascular endothelial cells (VECs), and smooth muscle cells (VSMCs), in the inflammation associated with psoriasis, a skin disease whose causes are not fully understood.
  • A comprehensive analysis of skin samples from psoriasis patients revealed distinct types of fibroblasts, VECs, and VSMCs that are more prevalent in lesional skin, indicating a shift towards inflammatory and angiogenesis-promoting activities in these cells.
  • The study concludes that the interactions between these stromal cells contribute to the pathological changes in psoriasis vulgaris, suggesting that targeting these cells may help improve the inflammatory environment associated with the disease.
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Capacitive deionization (CDI) offers a cost-effective and low-energy method for selective removal of Pb from drinking water. Modifying CDI electrode surfaces with functional groups presents a versatile approach to enhancing selective ion adsorption capacity. However, a comprehensive understanding of the selectivity and removal efficiency of Pb among diverse functional groups remains unexplored.

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Understanding the environmental behavior of thallium (Tl) is crucial due to its high toxicity and increasing anthropogenic presence. This study investigated the adsorption and redox behaviors of Tl(I) with acid birnessite (AcBi) in the presence of 1,4-piperazine-diethanesulfonic acid (PIPES) and goethite under diffusion-limited conditions using Donnan reactors in aerobic and anaerobic environments. Our findings indicate that Tl(I) preferentially adsorbs onto AcBi, with capacities 20 to 100 times higher than onto goethite, even when AcBi is partial reduced by PIPES.

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  • Plant grafting with dwarfing rootstocks like "Pd1" significantly impacts sweet cherry cultivation, affecting the growth characteristics of the 'Shuguang2' variety.
  • The study found that the Pd1 rootstock reduces gibberellin (GA) and auxin (IAA) levels in the scions and alters the methylation patterns of specific genes, suggesting a relationship between rootstock type and gene expression regulation.
  • Analysis revealed that DNA methylation significantly influences the activity of hormone-related genes, with hypermethylation in dwarfing plants linked to reduced growth potential in comparison to normal scions.
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This study explores the fusion of a field-effect transistor (FET), a paper-based analytical cartridge, and the computational power of deep learning (DL) for quantitative biosensing via kinetic analyses. The FET sensors address the low sensitivity challenge observed in paper analytical devices, enabling electrical measurements with kinetic data. The paper-based cartridge eliminates the need for surface chemistry required in FET sensors, ensuring economical operation (cost < $0.

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Background: Previous studies have established a correlation between the pathogenesis of oxidative stress and sarcopenia. The Oxidative Balance Score (OBS) is an integrated measure that reflects the overall balance of antioxidants and pro-oxidants in dietary components and lifestyle. However, there are limited reports on the association between OBS and lean mass and the impact of protein intake on the association between OBS and lean mass.

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  • The study investigates the relationship between non-high-density lipoprotein to high-density lipoprotein cholesterol ratio (NHHR) and the risk of low muscle mass, particularly in middle-aged Americans.
  • It utilizes data from the National Health and Nutrition Examination Survey (NHANES) and employs advanced statistical methods to find significant associations.
  • Findings reveal that specific NHHR values are linked to increased risks for low muscle mass, suggesting NHHR could serve as a predictive marker for this condition, warranting further research.
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Floral bud induction is of great importance for fruit crops, which may substantially affect fruit yield. Previously, a FLOWERING BHLH (FBH) transcription factor gene HpbHLH70 was identified in pitaya (Hylocereus polyrhizus) as subjected to drought stress. In present work, HpbHLH70 was found predominantly activated in pitaya anthers.

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Lung adenocarcinoma (LUAD) is a leading cause of cancer-related deaths, and improving prognostic accuracy is vital for personalised treatment approaches, especially in the context of immunotherapy. In this study, we constructed an artificial intelligence (AI)-driven stemness-related gene signature (SRS) that deciphered LUAD prognosis and immunotherapy response. CytoTRACE analysis of single-cell RNA sequencing data identified genes associated with stemness in LUAD epithelial cells.

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As a stochastic perturbation, the inter-core crosstalk (IC-XT) severely distorts the signal in multi-core fibers (MCF), especially for long-haul transmission. How to quickly measure and monitor the IC-XT online for an MCF-based space division multiplexing (SDM) system is of special importance. In this paper, we introduce the technology of auxiliary management and control channel (AMCC) to online monitor the IC-XT of MCF, in which the unique advantage of low-frequency auxiliary management and control signal is fully utilized with the limited influence on high-speed data transmission.

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Two-dimensional nanomaterials such as reduced graphene oxide (rGO) have captured significant attention in the realm of field-effect transistor (FET) sensors due to their inherent high sensitivity and cost-effective manufacturing. Despite their attraction, a comprehensive understanding of rGO-solution interfaces (specifically, electrochemical interfacial properties influenced by linker molecules and surface chemistry) remains challenging, given the limited capability of analytical tools to directly measure intricate solution interface properties. In this study, we introduce an analytical tool designed to directly measure the surface charge density of the rGO-solution interface leveraging the remote floating-gate FET (RFGFET) platform.

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Unlabelled: Sweet cherry ( L.) is one of the most economically important fruits in the world. However, severe fruit abscission has brought significant challenges to the cherry industry.

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Enhancing silicate weathering to increase oceanic alkalinity, thereby facilitating the absorption of atmospheric carbon dioxide (CO), is considered a highly promising technique for carbon sequestration. This study aims to evaluate the feasibility and potential of olivine-based ocean alkalinity enhancement (OAE) for the removal of atmospheric CO and its storage in seawater as bicarbonates in the East and South China Seas (ESCS). A particular focus is placed on the potential ecological impacts arising from the release of nickel (Ni) and chromium (Cr) during the olivine weathering process.

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The flower bud differentiation plays a crucial role in cherry yield and quality. In a preliminary study, we revealed the promotion of spermidine (Spd) in bud differentiation and quality. However, the molecular mechanism underlying Spd regulating cherry bud differentiation remains unclear.

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The increasing intensity of human activities has led to a critical environmental challenge: widespread metal pollution. Manganese (Mn) oxides have emerged as potentially natural scavengers that perform crucial functions in the biogeochemical cycling of metal elements. Prior reviews have focused on the synthesis, characterization, and adsorption kinetics of Mn oxides, along with the transformation pathways of specific layered Mn oxides.

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The DOF (DNA binding with one finger) has multiple functions in plants. However, it has received little attention in the research field of cherries. In this study, the evolutionary relationship and molecular characterization of DOF in four cherry species were analyzed, revealing its expression pattern in sweet cherry.

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Background: The basic helix-loop-helix (bHLH) gene family is one of plants' largest transcription factor families. It plays an important role in regulating plant growth and abiotic stress response.

Results: In this study, we determined that the PavbHLH28 gene participated in cold resistance.

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Gut microbes exhibit complex interactions with their hosts and shape an organism's immune system throughout its lifespan. As the largest secondary lymphoid organ, the spleen has a wide range of immunological functions. To explore the role of microbiota in regulating and shaping the spleen, we employ scRNA-seq and Stereo-seq technologies based on germ-free (GF) mice to detect differences in tissue size, anatomical structure, cell types, functions, and spatial molecular characteristics.

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Accelerated urbanization and industrialization have led to an alarming increase in the generation of wastewater with complex chemical contents. Industrial wastewaters are often a primary source of water contamination. The chemical characterization of different industrial wastewater types is an essential task to interpret the chemical fingerprints of wastewater to identify pollution sources and develop efficient water treatment strategies.

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Rapid diagnosis of coronavirus disease 2019 (COVID-19) is key for the long-term control of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) amid renewed threats of mutated SARS-CoV-2 around the world. Here, we report on an electrical label-free detection of SARS-CoV-2 in nasopharyngeal swab samples directly collected from outpatients or in saliva-relevant conditions by using a remote floating-gate field-effect transistor (RFGFET) with a 2-dimensional reduced graphene oxide (rGO) sensing membrane. RFGFET sensors demonstrate rapid detection (<5 min), a 90.

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Carbon dioxide (CO) emitted by human activities not only brings about a serious greenhouse effect but also accelerates global climate change. This has resulted in extreme climate hazards that can obstruct human development in the near future. Hence, there is an urgent need to achieve carbon neutrality by increasing negative emissions.

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Flower bud differentiation is crucial to reproductive success in plants. In the present study, RNA-Seq and nutrients quantification were used to identify the stage-specific genes for flower bud differentiation with buds which characterize the marked change during flower bud formation from a widely grown Chinese cherry ( L.) cultivar 'Manaohong'.

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The development of marine carbon sequestration project has an important potential for carbon neutralization in the short-term (several decades). Marine carbon sequestration technology is based on biological and carbonate pumps to increase particulate organic carbon and authigenic insoluble carbonates to the deep sea or seafloor, aiming to achieve permanent carbon sequestration. Particularly, chemical carbon sequestration technology based on carbonate pump is proposed and considered to achieve short-term marine carbon sequestration in recent years.

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