Publications by authors named "Zhuang Qianwei"

Purpose: To evaluate the efficacy and safety of ultrasound hyperthermia combined with TPF chemotherapy for advanced oral squamous cell carcinoma in the elderly.

Methods: Nineteen elderly patients who had definite pathological diagnosis were enrolled in this clinical trail from June 2017 to January 2020. Docetaxel (75 mg/m2) + cisplatin (75 mg/m2) were given on the 1st day , and 5,Fu (750 mg/m2) on the 1st to 5th day of the cycle.

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Background: Hyperthermia has been reported to cause cancer stage regression, thus providing surgical opportunities in patients with unresectable tumors and improving the quality of life of patients by preserving certain organs.

Methods: A prospective open-label phase II trial was conducted to evaluate the efficacy of hyperthermia combined with induction chemotherapy in patients with locally advanced resectable oral squamous cell carcinoma (OSCC). Patients received hyperthermia combined with two cycles of 5-fluorouracil, cisplatin, and docetaxel (TPF) induction chemotherapy regimens or TPF induction chemotherapy alone, followed by radical surgery with postoperative radiotherapy.

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Purpose: To explore the safety and efficacy of ultrasound hyperthermia combined with chemotherapy and radical operation for advanced oral squamous cell carcinoma (OSCC).

Methods: Nine patients who had definite pathological diagnosis were enrolled in this clinical trail from 2015 to 2016. All patients underwent ultrasound hyperthermia combined with chemotherapy before radical operation.

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Purpose: To investigate the therapeutic effects of different doses of I radioactive particle brachytherapy on oral cancer.

Methods: Between September 2012 and September 2015, 78 patients with oral cancer who received I radioactive particle brachytherapy for the first time in our hospital were enrolled in this study. Patients were divided into high dose (≥3) and low dose (<3) groups.

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Background: Severe cranio-maxillofacial trauma requires the utilization of alternative airway management techniques when oral and nasal routes of tracheal intubation are either not possible or contraindicated.

Methods: This retrospective study evaluated the techniques of submental intubation, retromolar intubation and tracheostomy in terms of their frequency of use, time required, costs involved and associated complications in a total of 200 patients.

Results: Frequency of utilization of alternative airway management techniques was 3.

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The present study aimed to evaluate efficacy and adverse effects of Nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in the treatment of advanced oral carcinoma. Nine patients with advanced oral carcinoma were treated with Nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen (test group). The treatment was given as follows: Nimotuzumab 200 mg, given as intravenous infusion once a week for 6 weeks; docetaxel and cisplatin, 75 mg/m(2) each, on day 1 only; 5-fluorouracil, 750 mg/m(2) infused continually for 8 h, used from day 1 to 5; the total cycle was for 21 days.

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Article Synopsis
  • The study evaluated the effectiveness of (125)I radioactive seed implantation combined with a prosthetic denture in treating patients with glandule palatine malignancy.
  • Ten patients underwent tumor removal, followed by implantation of radioactive seeds and fitting of a dental prosthesis to address tissue defects.
  • Results showed no tumor recurrence or metastasis in the follow-up period, along with significant improvements in speech, chewing, and facial aesthetics, indicating a successful treatment approach.
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Infantile fibromatosis (IF) is a benign, nonmetastasizing but locally aggressive tumor. Pterygomandibular space is deep and obscure, and IF in this space is seldom reported. We describe a typical case of IF in the pterygomandibular space that occurred in a 3-year-old girl.

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Objective: Intraosseous mucoepidermoid carcinoma of jaws is rare, and management of the disease remains poorly understood. The aim of this study was to assist the diagnosis and treatment of the tumor.

Study Design: The records of clinical data and follow-up information were collected from 1996 to 2010 and retrospectively analyzed for clinical features, surgical intervention, and prognosis.

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Aim Of The Study: The current study aimed to evaluate the clinical efficacy and adverse effects of small doses of propranolol intervention therapy for infants with infantile facial hemangioma in the proliferation stage.

Material And Methods: A total of 22 patients including 9 males and 13 females with an average age of 5.5 months were enrolled.

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Article Synopsis
  • Osteoradionecrosis of the mandible is a serious complication that can occur after radiation therapy for head and neck cancers, characterized by symptoms like pain, lesions, and bone death.
  • The condition is linked to radiation-induced fibrosis, which causes damage to various body tissues after treatment and has a dose-dependent relationship with osteoradionecrosis.
  • Research is needed to find better management and prevention strategies for osteoradionecrosis related to radiation therapy.
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We report here a template method for the fabrication of nanochannels with water-dissolvable NaNH(4)Mo(3)O(10).H(2)O nanowires as the sacrificial material. By using these nanowires, which have diameters ranging from 20 to 150 nm and lengths up to a hundred microns, we have demonstrated that it is possible to obtain nanochannels with the desired shape of cross section, and desired types of channel material, such as metals and oxides.

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