Association of thrombocytopenia with immune checkpoint inhibitors: a large-scale pharmacovigilance analysis based on the data from FDA adverse event reporting system database.

An increasing number of immune-related adverse events (irAEs) induced by immune checkpoint inhibitors (ICIs) have been reported during clinical treatment. We aimed to explore the clinical characteristics of patients with ICIs-induced ITP under different therapeutic strategies based on the FAERS database and explore the potential biological mechanisms in combination with TCGA pan-cancer data. Data from FAERS were collected for ICIs adverse reactions between January 2012 and December 2022.

An iterative transfer matrix approach for estimating the sound speed and attenuation constant of air in a standing wave tube.

In this work, an iterative method based on the four-microphone transfer matrix approach was developed for evaluating the sound speed and attenuation constant of air within a standing wave tube. When the air inside the standing wave tube is treated as the material under test, i.e.