The development of the non-ferrous metal industry is generating increasingly large quantities of wastewater containing heavy metals (e.g., Sb).
View Article and Find Full Text PDFChina is the largest producer and consumer of geese with significant social and economic value in agriculture. The Jilin White Goose, known for its excellent egg-laying and reproductive characteristics, is a prominent breeding breed in the northeast of China widely used for cross-breeding.Gonad development is a complex process, which will differentiate into testes or ovaries, thus affecting sex determination.
View Article and Find Full Text PDFCarrot ( L.) is an important vegetable crop that is rich in carotenoids and is widely cultivated throughout the world. Alternaria leaf blight (ALB), caused by infection with (), is the most serious fungal disease in carrot production.
View Article and Find Full Text PDFOcean exploration-oriented temperature and salinity (TS) sensor based on bend-insensitive microfiber Mach-Zehnder interferometer (MMZI) is proposed and demonstrated in a marine environment. To solve the demodulation problem induced by the narrow waveband of the spectrometer used in the sea trial, a MMZI sensor is calibrated and demodulated by machine learning method. Results show that even if the wavelength range used in demodulation is as small as tens of nanometers, a relatively accurate demodulation can still be achieved.
View Article and Find Full Text PDFDynamic LR and QR factorization are fundamental problems that exist widely in the control field. However, the existing solutions under noises are lack of convergence speed and anti-noise ability. To this end, this paper incorporates the advantages of Dynamic-Coefficient Type (DCT) and Integration-Enhance Type (IET) Zeroing Neural Dynamic (ZND), and proposes an Adaptive and Robust-Enhanced Neural Dynamic (AREND).
View Article and Find Full Text PDFAim: Mitochondrial dysfunction is a critical factor in the pathogenesis of septic cardiomyopathy (SCM). Mitochondrial anchored protein ligase (MAPL), a small ubiquitin-like modifier (SUMO) E3 ligase, plays a significant role in mitochondrial function. However, the role of MAPL in SCM remains unclear.
View Article and Find Full Text PDFA robust strain sensor is demonstrated based on a microfiber Mach-Zehnder interferometer (MMZI) encapsulated by the polymer polydimethylsiloxane (PDMS). Benefiting from the low Young's modulus of PDMS, both a robust structure and high sensitivity can be realized based on three different encapsulations. In the experiment, the proposed sensors are fabricated and tested with strain sensitivities ranging from -20.
View Article and Find Full Text PDFLung ischemia-reperfusion injury (IRI) stands as the primary culprit behind primary graft dysfunction (PGD) after lung transplantation, yet viable therapeutic options are lacking. In the present study, we used a murine hilar clamp (1 h) and reperfusion (3 h) model to study IRI. The left lung tissues were harvested for metabolomics, transcriptomics, and single-cell RNA sequencing.
View Article and Find Full Text PDFThe aim of this study is to explore the effects and specific mechanisms of heparanase on angiogenesis and iron deficiency anemia in TP53 mutant cancer. For this purpose, we conducted in vitro cell experiments and in vivo animal experiments respectively. In this study, we first analyzed the differential expression of heparanase in TP53 wild-type and mutant cells, and analyzed its effects on iron removal and angiogenesis in two types of CALU-1 and NCI-H358 cells.
View Article and Find Full Text PDFPurpose: To determine the performance of T2* cartilage mapping in diagnosing and assessing disease activity in early axial spondyloarthritis (axSpA), and to investigate the interaction of cartilage damage with clinical characteristics, sacroiliitis MRI scorings, and diffusion metrics.
Materials And Methods: This prospective study included 83 axSpA patients and 37 no-axSpA patients. Clinical characteristics, the Assessment of SpondyloArthritis International Society-defined active sacroiliitis on MRI, and T2* values were recorded.
Objective: To explore the clinical effectiveness of reconstructing laryngeal function using thyroid cartilage fenestration and "draw-out" resection, supplemented by internal fixation with titanium microplates in early glottic carcinoma.
Methods: Data from 99 patients with glottic carcinoma treated in the Second Affiliated Hospital of Fujian Medical University between January 2014 and September 2021 were retrospectively analyzed. Forty-eight patients who underwent thyroid cartilage fenestration and resection followed by internal fixation with titanium microplates for laryngeal function reconstruction were assigned to the thyroid cartilage fenestration group (TCF group), while the other 51 patients who underwent sternohyoid muscle and fascia repair for laryngeal function reconstruction were assigned to the sternohyoid muscle repair group (SMR group).
The in-situ high-frequency monitoring of total nitrogen (TN) and total phosphorus (TP) in rivers is a challenge and key to instant water quality judgment and early warning. Based on the physical and chemical association between TN/TP and sensor-measurable predictors, we proposed a novel "indirect" measurement method for TN and TP in rivers. This method combines the timeliness of multi-sensor and the accuracy of intelligent algorithms, utilizing 188,629 data sets from 131 water monitoring stations across China.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) poses a formidable challenge in oncology due to its aggressive nature and limited treatment options. Although doxorubicin, a widely used chemotherapeutic agent, shows efficacy in TNBC treatment, acquired resistance remains a significant obstacle. Our study explores the role of MALSU1, a regulator of mitochondrial translation, in TNBC and its impact on cell proliferation and doxorubicin resistance.
View Article and Find Full Text PDFIn natural language processing, fact verification is a very challenging task, which requires retrieving multiple evidence sentences from a reliable corpus to verify the authenticity of a claim. Although most of the current deep learning methods use the attention mechanism for fact verification, they have not considered imposing attentional constraints on important related words in the claim and evidence sentences, resulting in inaccurate attention for some irrelevant words. In this paper, we propose a syntactic evidence network (SENet) model which incorporates entity keywords, syntactic information and sentence attention for fact verification.
View Article and Find Full Text PDFThe post-surgical melanoma recurrence and wound infections have persistently troubled clinical management. Piezocatalytic therapy features high efficiency in generating reactive oxygen species (ROS) for tumor therapy, but it faces limitations in piezoelectricity and redox-active site availability. Herein, Fe-doped ultrathin BiTiO nanosheets (designated as Fe-UBTO NSs) with synergistically piezo-chemocatalytic activity are engineered for antitumor and antibacterial treatment against cutaneous melanoma.
View Article and Find Full Text PDFAging (Albany NY)
April 2024
Ferroptosis, an iron-triggered modality of cellular death, has been reported to closely relate to human aging progression and aging-related diseases. However, the involvement of ferroptosis in the development and maintenance of senescent cells still remains elusive. Here, we established a doxorubicin-induced senescent HSkM cell model and found that both iron accumulation and lipid peroxidation increase in senescent cells.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) poses significant challenges in treatment due to its aggressive nature and limited therapeutic targets. Understanding the underlying molecular mechanisms driving TNBC progression and chemotherapy resistance is imperative for developing effective therapeutic strategies. Thus, in this study, we aimed to elucidate the role of pyrroline-5-carboxylate reductase 3 (PYCR3) in TNBC pathogenesis and therapeutic response.
View Article and Find Full Text PDFBio-based coating materials have received increased attention because of their low-cost, environmentally friendly, and sustainable properties. In this paper, a novel coating material was developed to coat ureas using bio-based coating material derived from liquefied eggplant branches to form controlled-release ureas (CRUs). Also, the optimum proportion of liquefier was studied.
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