Publications by authors named "Zhu-rong Luo"

Objectives: Although previous studies have demonstrated the relationship between ABO blood groups and cardiovascular disease, the association of ABO blood type with spontaneous recanalization (SR) in patients with acute myocardial infarction (AMI) has not been previously investigated.

Methods: We performed an initial exploratory study on the association of ABO blood groups with the presence of SR in 1209 patients with AMI. They were divided into two groups according to the thrombolysis in myocardial infarction (TIMI) grades: no-SR group (TIMI 0-1, n = 442) and SR group (TIMI 2-3, n = 767).

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Ligustrazine, a compound extracted from roots of Ligusticum chuanxiong, is widely used in Chinese traditional medicine to treat cardiac and cerebrovascular diseases and pain, including angina. The mechanism(s) of ligustrazine's effect to reduce angina is not clear. Angina is mediated by cardiac afferent sensory neurons.

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Article Synopsis
  • The study aimed to explore how the osteoprotegerin (OPG) system relates to acute coronary syndrome (ACS) and its traditional Chinese medicine (TCM) classification.
  • It involved 210 ACS patients and 200 stable angina patients, measuring serum OPG and its ligand sRANKL, finding significant elevations in ACS and stable angina compared to controls.
  • The results showed that as the number of diseased coronary vessels increased, OPG levels rose while sRANKL levels decreased, correlating with TCM classifications where certain syndromes showed significantly higher OPG levels.
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