Publications by authors named "Zhu-Qing Tian"
Introduction: Irisin is a newly discovered myokine which links exercise to inflammation and inflammation-related diseases through macrophage regulation. However, the effect of irisin on the activity of inflammation related immune cells (such as neutrophils) has not been clearly described.
Objectives: The objective of our study was to explore the effect of irisin on the neutrophil extracellular traps (NETs) formation.
Article Synopsis
- The study investigates the role of serum glycosylated hemoglobin A1c (HbA1c) levels in assessing the severity and outcomes of acute pancreatitis (AP), focusing on two groups: normal HbA1c levels (<6.5%) and high levels.
- It was found that higher HbA1c levels correlate with increased disease severity, complications, and the risk of organ failure in AP patients, with the optimal cutoff for predicting organ failure at 7.05%.
- The results suggest that better glycemic control may lead to improved outcomes in AP, emphasizing the importance of monitoring HbA1c levels prior to the onset of the condition.
Article Synopsis
- The study examines how elevated serum ferritin (SF) levels relate to the severity of acute pancreatitis (AP), noting SF is an indicator of oxidative stress and inflammation.
- An analysis of 200 AP patients revealed that nearly half had high SF levels, which were linked to a higher severity of the condition and increased systemic inflammatory response.
- The study concluded that SF levels can effectively predict the severity of AP and the likelihood of organ failure in affected patients.
Global burden of fungal infections and related health risk has accelerated at an incredible pace, and multidrug resistance emergency aggravates the need for the development of new effective strategies. is clinically the most ubiquitous pathogenic fungus that leads to high incidence and mortality in immunocompromised patients. Antimicrobial peptides (AMPs), in this context, represent promising alternatives having potential to be exploited for improving human health.
View Article and Find Full Text PDFCandida albicans is the most common human fungal pathogen in immunocompromised individuals. With the emergence of clinical fungal resistance, there is an urgent need to develop novel antifungal agents. AMP-17, a novel antimicrobial peptide from Musca domestica, has an antifungal effect against C.
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- The study aimed to examine how common fatty pancreas is in Yangzhou, China, and what factors contribute to its development.
- Out of 2,093 participants, 56 (2.7%) were found to have fatty pancreas after excluding incomplete data, leading to a total of 1,228 subjects analyzed.
- Results indicated that older age, central obesity, and fatty liver disease are significant independent risk factors for developing fatty pancreas.