Gracillosides A-F, six new 8,14-seco-pregnane glycosides from Adelostemma gracillimum.

Six new 8,14-seco-pregnane glycosides, gracillosides A-F (1-6), were isolated from the roots of Adelostemma gracillimum (Asclepiadaceae). All of them had the same aglycone as gracigenin with a rare 8,14-seco-pregnane type skeleton in nature and possessed an oligosaccharide chain consisting of four to six sugar units at C-3 of the aglycone. Their structures were determined on the basis of detailed spectroscopic analysis and chemical evidence.

Two new triterpenoid saponins from Glochidion puberum.

Two new triterpenoid saponins, puberosides A and B, were isolated from the aerial parts of Glochidion puberum. Their structures were elucidated as 3alpha-[(O-beta-D-glucopyranosyl-(1-->3)-O-alpha-L-arabinopyranosyl)oxy]-22alpha-benzoyloxy-olean-12-ene-16alpha,28-diol (1) and 3alpha-[(O-beta-D-glucopyranosyl-(1-->3)-O-alpha-L-arabinopyranosyl)oxy]-28-benzoyloxy-olean-12-ene-16alpha,22alpha-diol (2) by analysis of their spectroscopic data.

Cipadonoid A, a novel limonoid with an unprecedented skeleton, from Cipadessa cinerasecns.

Cipadonoid A ( 1), a novel limonoid with an unprecedented skeleton, was isolated from the leaves of Cipadessa cinerasecns. Its structure and relative configuration were determined by spectroscopic analysis and computer modeling. 1 represents a new type of limonoid, characterized by a rearranged tetrahydropyranyl ring B incorporating usually exocyclic C-30.

Three new lignan glycosides from Mananthes patentiflora.

Three new lignan glycosides, mananthosides I-K (1-3), were isolated from the ethanolic extract of the aerial part of Mananthes patentiflora. The structure elucidation of these compounds was mainly established on the basis of 1D NMR, 2D NMR and HR-MS spectroscopic analysis.