Publications by authors named "Zhu-Jun Cao"

Chronic HBV infection patients who do not conform to any of the usual immune states are regarded as 'grey zone' patients. We aimed to investigate the proportion of chronic HBV infection patients in the grey zone, and evaluate the clinical characteristics and liver pathological changes in grey zone patients. Clinical data of 1391 treatment-naive chronic HBV infection patients with liver biopsy were collected.

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Article Synopsis
  • * Aim: The goal is to assess how bacterial infections affect the survival rates and outcomes of HBV-related decompensated cirrhosis patients, especially those admitted with or without ACLF.
  • * Results: Out of 1,281 patients studied, those with bacterial infections had significantly lower survival rates and a higher chance of developing ACLF. Notably, pneumonia was linked to higher mortality in ACLF patients, indicating the need for close monitoring of infections in this
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Background: Hepatocyte death, either apoptosis or necrosis, is closely associated with hepatic inflammation and fibrosis.

Aims: To investigate the potential values of hepatocytes death biomarker, M30 (apoptosis) and M65 (total death) in predicting histological lesions in chronic hepatitis B virus (HBV) infection.

Methods: Total 201 treatment-naïve patients were prospectively recruited.

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