Publications by authors named "Zhu-Hua Ni"
Objective: Patients presenting with acute myocardial infarction (AMI) with prior digestive system disease are more likely to suffer from gastrointestinal (GI) bleeding than those without these diseases. However, few articles reported how the different conditions of the digestive tract produced different risks of GI bleeding.
Methods: A single-center study on 7464 patients admitted for AMI from December 2010 to June 2019 in the Beijing Chaoyang Heart Center was retrospectively examined.
Article Synopsis
- The study aimed to assess the long-term outcomes and mortality risk factors in patients with acute STEMI who also had a chronic total occlusion (CTO) in a non-infarct-related artery (IRA).
- The analysis involved 323 patients, divided into CTO (97) and non-CTO (236) groups, focusing on major adverse cardiovascular and cerebrovascular events (MACCE) over time.
- Key findings highlighted that the CTO group had significantly higher mortality rates, with age 65+, presence of CTO, higher in-hospital Killip class, renal insufficiency, and stress ulcers being major independent predictors of long-term mortality.
Objective: The aim of this study was to compare the 2-year clinical outcomes of overlapping second-generation everolimus-eluting stents (EES) with those of overlapping resolute zotarolimus-eluting stents (R-ZES) in the treatment of long coronary artery lesions.
Materials And Methods: This retrospective analysis included 256 patients treated with overlapping EES (n=121) and R-ZES (n=135) for long coronary artery lesions (total stent length per lesion ≥34 mm). Study endpoints included major adverse cardiac events (MACE) defined as the composite of cardiac death, myocardial infarction, and target-vessel revascularization (TVR), as well as target-lesion revascularization and definite stent thrombosis separately at 2 years.
[Single center experience of primary percutaneous coronary intervention on left main disease complicated by acute myocardial infarction].
Zhonghua Xin Xue Guan Bing Za Zhi
October 2012
Objective: To explore the clinical effect of primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) induced by left main artery total or subtotal occlusion.
Methods: Between January 1995 and June 2010, there were 28 AMI patients [24 males, mean age (61.5 ± 2.
Background: Primary percutaneous coronary intervention (PCI) is the best treatment of choice for acute ST segment elevation myocardial infarction (STEMI). This study aimed to determine the clinical outcomes of tirofiban combined with the low molecular weight heparin (LMWH), dalteparin, in primary PCI patients with acute STEMI.
Methods: From February 2006 to July 2006, a total of 120 patients with STEMI treated with primary PCI were randomised to 2 groups: unfractionated heparin (UFH) with tirofiban (group I: 60 patients, (61.
Objective: This prospective random control study was performed to compare the efficacy and safety of primary percutaneous coronary intervention (PCI) with biodegradable polymer (Excel) and with durable polymer (Cypher Select) sirolimus-eluting stents in patients with acute ST-elevation myocardial infarction (STEMI).
Methods: Consecutive patients with STEMI underwent primary PCI were randomly divided into Cypher group (n = 113) and Excel group (n = 115). The primary endpoints were major adverse cardiac events (MACE, including death, reinfarction and target vessel revascularization) within 12 months.
Objective: To explore the prognostic impact of post primary percutaneous coronary intervention (PCI) reperfusion status on outcome in patients with acute ST-elevation myocardial infarction (STEMI).
Methods: A retrospective analysis was performed in 964 patients undergoing primary PCI for STEMI. Electrocardiogram and TIMI myocardial perfusion grade (TMPG) were analyzed by reader blinded to the clinical course.
Background: The clinical outcome of percutaneous coronary intervention (PCI) is poorer in women than that in men. This study aimed at comparing the impact of gender difference on the strategy of primary PCI in patients with acute ST-segment elevation myocardial infarction (STEMI).
Methods: Two hundred and fifty-nine patients with STEMI who underwent primary PCI within 12 hours of symptom onset were enrolled.
Objective: To investigate the clinical and angiographic morphologic features leading to worse myocardial reperfusion in patients with acute ST-elevation myocardial infarction (STEMI) after primary percutaneous coronary intervention (PCI).
Methods: Clinical and angiographic data were collected and logistic regression analysis performed in 964 STEMI patients undergoing primary PCI.
Results: Logistic regression analysis showed that non-anterior myocardial infarction, pain to balloon time and degree of cardiac dysfunction were clinical predictive factors while fade-out type of angiographic morphology, ie, presence of accumulated thrombus proximal to the occlusion was angiographic predictive factor of worse reperfusion for STEMI patients post PCI.
[Very late angiographic stent thrombosis after sirolimus-eluting stent implantation at 54 months].
Zhonghua Xin Xue Guan Bing Za Zhi
February 2008
Objective: To observe the safety and long-term efficacy of Cypher stent versus bare metal stents (BMS) in patients with STEMI.
Methods: From Dec 2002 to Mar 2005, clinical and angiographic data of 407 consecutive patients with STEMI treated with Cypher stent (n = 131) or BMS (n = 276) were analyzed and followed up for a mean period of 28.7 +/- 11.
Objective: To observe the effect of reperfusion therapy on the prognosis of acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) in reperfusion era.
Methods: 89 cases of AMI with CS were included with 57 male and 32 female. 50 cases received conservative therapy and 39 cases reperfusion therapy.
Background: Postconditioning has been shown to reduce infarct size during reperfusion (< 72 hours). However, it is unknown whether the infarct size reduction with postconditioning is a long-term effect after clinical percutaneous coronary intervention (PCI). The present study tested the hypothesis that postconditioning during primary PCI preserves global cardiac function and reduces infarct size in patients after prolonged reperfusion.
View Article and Find Full Text PDFObjective: To compare the effects on MACE of intracoronary or intravenous tirofiban bolus administration in patients with acute ST-elevation myocardial infarction (STEMI).
Methods: A total of 60 consecutive STEMI patients ready to receive primary PCI were randomly assigned to intracoronary tirofiban bolus (10 microg/kg) prior to the first balloon inflation (Group IC) or to intravenous tirofiban bolus at the same dose prior to coronary angiography (Group IV), followed by a 36-hours IV tirofiban (0.15 microg .
[Very late stent thrombosis after implantation of sirolimus eluting coronary stents].
Zhonghua Xin Xue Guan Bing Za Zhi
April 2007
Objective: To analyze the clinical date of 4 patients who developed very late stent thrombosis after implantation of sirolimus eluting stents.
Methods: From Oct. 2002 to Aug.
Objective: To evaluate the prognostic value of ST resolution (STR) measured in a single ECG lead obtained early after primary PCI in patients with ST-elevation myocardial infarction (STEMI).
Methods: In this retrospective study, STR, MACE and factors contributed to STR were analyzed in 964 patients underwent primary PCI post STEMI. The ECGs analysis was made by technicians blinded to the clinical data.
Objective: To observe the safety and efficiency of ultra-early glycoprotein IIb/IIIa receptor blockade tirofiban use in patients with acute ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI).
Methods: From April 2005 to April 2006, 158 consecutive AMI patients (117 males, mean age of 58.8 +/- 25.
Objective: To investigate the feasibility, safety and efficacy of Cypher drug-eluting stent implanted after the emergency percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI).
Methods: From Nov. 2002 to Dec.