Publications by authors named "Zhu-Hua Hu"

Background: Blastocystis is ubiquitous presence in animals and humans worldwide and has a high level genetic diversity. The aim of this study was to conduct a summary of Blastocystis prevalence, subtypes (STs) in humans and animals in China and depict their distribution.

Methods: We searched for the articles related to epidemiology of Blastocystis in humans and animals throughout China which published from January 1, 1990, to July 31, 2019 in the following databases: PubMed, China National Knowledge Infrastructure (CNKI) and Wanfang database.

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Objective: To develop a bionic animal skin and evaluate its detective effect of cercariae so as to provide a new technique for the monitoring of the schistosome susceptibility water body.

Methods: A bionic animal skin was made with pigskin and the experiments were carried out for evaluating its detective effects of cercariae in laboratory and simulate fields, and at the same time, the sentinel mouse method was used as the control.

Results: In the laboratory, the cercariae were found in 10-, 30-, 60-cercaria subgroups in the bionic animal skin group after 1 and 2 hours, but the cercariae were found only in the 60-cercaria subgroup in the sentinel mouse group.

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Objective: To understand the present situation of the chronic schistosomiasis patients' knowledge, attitude and practice on schistosomiasis control in Nanchang City.

Methods: The knowledge, attitude and values on schistosomiasis control of 523 chronic schistosomiasis patients in Nanchang County, Jinxian County and Xinjian District in the Poyang Lake District were investigated with questionnaires. And the accuracy rates of the knowledge, attitude and practice among the patient groups of different counties, genders, age groups, occupations and educational levels were analyzed.

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Objective: To investigate the endemic situation of human infection in Nanchang City in 2014 and analyze the influencing factors, so as to provide the evidence for control measures.

Methods: The high-risk population of infection in Nanchang City was collected as an experiment group, and a control group was settled with the ratio of 1∶1. The serum tests and epidemiology surveys were conducted simultaneously, and the influencing factors were analyzed.

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Objective: To evaluate the effect of schistosomiasis control in towns that had reached the criteria of infection controlled in Nanchang City.

Methods: The residents and livestock of 14 towns that had reached the criteria of infection controlled in Nanchang, Xinjian and Jinxian counties of Nanchang City were sampled to investigate the schistosomiasis endemic situation, Oncomelania hupensis snail status, and data of schistosomiasis control work.

Results: The positive rate of serum tests of the residents was 2.

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Article Synopsis
  • The study aimed to understand how the calcium cyanamide synthetic drug affects the morphology of Schistosoma japonicum eggs, with the goal of exploring the drug's mechanism against schistosome eggs.
  • Researchers mixed the drug with cattle feces containing the eggs and monitored changes over a week, comparing treated samples with blank controls.
  • Results showed that the treatment caused significant damage to the eggs, including color changes, atrophy of miracidia, and thickening of egg shells, with the effects worsening over time.
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Objective: To understand the endemic regulation of acute schistosomiasis in Nanchang City of Jiangxi Province from 2005 to 2012 so as to provide the reference for policy-making of schistosomiasis control.

Methods: The data of acute schistosomiasis were collected and analyzed with the descriptive epidemiology method in Nanchang City from 2005 to 2012.

Results: A total of 52 acute schistosomiasis cases were reported in Nanchang City from 2005 to 2012.

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Dechlorinated water (100 ml, 30 degrees C) was put into a plate (diameter 15 cm), and 1% niclosamide spreading oil 5 microl was added, then a ring of Schistosoma japonicum cercariae were picked up to the plate. The time of killing all the cercariae was observed at three time points (immediately, 24, 48 h), and the dechlorinated water was used as control. The results showed that schistosome cercariae were all killed in three minutes by 1% niclosamide spreading oil at the three time points.

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Objective: To explore the influencing factors of the significant decrease of snail densities in Poyang Lake region, Nanchang City, 2011.

Methods: According to the elevation of the environment, 5 grasslands where there were high snail densities and their elevations were from 14 to 17 m were selected as study areas. The data of snails in the past three years and the hydrological information in the past five years were collected and analyzed.

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