Cloud-Edge-End Collaborative Federated Learning: Enhancing Model Accuracy and Privacy in Non-IID Environments.

Cloud-edge-end computing architecture is crucial for large-scale edge data processing and analysis. However, the diversity of terminal nodes and task complexity in this architecture often result in non-independent and identically distributed (non-IID) data, making it challenging to balance data heterogeneity and privacy protection. To address this, we propose a privacy-preserving federated learning method based on cloud-edge-end collaboration.

Real-Time Orbit Determination of Micro-Nano Satellite Using Robust Adaptive Filtering.

Low-performing GPS receivers, often used in challenging scenarios such as attitude maneuver and attitude rotation, are frequently encountered for micro-nano satellites. To address these challenges, this paper proposes a modified robust adaptive hierarchical filtering algorithm (named IARKF). This algorithm leverages robust adaptive filtering to dynamically adjust the distribution of innovation vectors and employs a fading memory weighted method to estimate measurement noise in real time, thereby enhancing the filter's adaptability to dynamic environments.

Comparative Analysis of Ca/Cation Antiporter Gene Family in and Enhanced Calcium Stress Tolerance via Heterologous Expression of RrCAX1a in Tobacco.

, a calciphilic species native to the mountainous regions of Southwest China, is renowned for its high vitamin C and bioactive components, making it valuable for culinary and medicinal uses. This species exhibits remarkable tolerance to the high-calcium conditions typical of karst terrains. However, the underlying mechanisms of this calcium resilience remain unclear.

Network Toxicology and Molecular Docking Analysis of Tetracycline-Induced Acute Pancreatitis: Unveiling Core Mechanisms and Targets.

Acute pancreatitis (AP), induced by tetracycline, a widely used antibiotic, poses significant clinical and toxicological challenges, yet its molecular mechanisms remain unclear. This study aims to promote drug toxicology strategies for the effective investigation of the putative toxicity and potential molecular mechanisms of antibiotic drugs through the study of tetracycline in AP. Using the SwissTargetPrediction, SEA Search, Super-PRED, GeneCards, Drugbank, Online Mendelian Inheritance in Man (OMIM), and Therapeutic Target Database (TTD), we identified 259 potential targets associated with tetracycline exposure and AP.

Diagnostic Accuracy of Antigen-Based Skin Tests (TBSTs) for Tuberculosis Infection Compared with TST and IGRA: A Network Meta-Analysis.

The aim of this study was to evaluate the diagnostic accuracy of the IGRA, TST, and TBST by combining diagnostic test accuracy (DTA) analysis and network meta-analysis (NMA) to increase the reliability and accuracy of diagnostic methods and promote the eradication of TB. An electronic search of the PubMed, Embase, and Cochrane databases was conducted, from the date of establishment to September 30, 2024. Data were synthesized with frequentist random-effects network meta-analyses, a single-group rate meta-analysis algorithm, and a bivariate mixed-effects logistic regression model.

Silicon Extraction from a Diamond Wire Saw Silicon Slurry with Flotation and the Flotation Interface Behavior.

Diamond wire saw silicon slurry (DWSSS) is a waste resource produced during the process of solar-grade silicon wafer preparation with diamond wire sawing. The DWSSS contains 6N grade high-purity silicon and offers a promising resource for high-purity silicon recycling. The current process for silicon extraction recovery from DWSSS presents the disadvantages of lower recovery and secondary pollution.

Genetic Diversity and Differentiation of Silkworm () Local Germplasm Resources in China and Uzbekistan.

Silkworm () is an economically significant insect that produces silk and makes important contributions to the development of silk-producing countries. The genetic diversity and unique adaptive traits of silkworm germplasm resources form the foundation for breeding efforts. In various geographical regions, silkworm have developed distinct traits through long-term adaptive selection.

Screening and Validation of Stable Reference Genes for qRT-PCR Analysis in (Coleoptera: Meloidae).

is a hypermetamorphic insect that mainly forage soybeans during the adult stage. However, the lack of appropriate references hinders our studying of the gene function in . In this study, referring to five computational tools (Ct value, geNorm, NormFinder, BestKeeper and RefFinder), the stability of 10 housekeeping genes (, , , , , , , , and ) was assessed by qRT-PCR under three different conditions (adult ages, tissues/organs and temperatures).

Scanning Electron Microscopy of the Proboscis and Associated Sensilla in (Esper, 1805) (Lepidoptera: Pieridae).

Morphological studies of the proboscis can provide valuable insights into the evolutionary adaptations of Lepidoptera. However, such research is relatively limited for Pieridae, a family that is significant both ecologically and economically. In this study, scanning electron microscopy (SEM) was employed to investigate the proboscis and associated sensilla of adult , with an emphasis on ultrastructural details and potential sex-specific differences.

LncSL: A Novel Stacked Ensemble Computing Tool for Subcellular Localization of lncRNA by Amino Acid-Enhanced Features and Two-Stage Automated Selection Strategy.

Long non-coding RNA (lncRNA) is a non-coding RNA longer than 200 nucleotides, crucial for functions like cell cycle regulation and gene transcription. Accurate localization prediction from sequence information is vital for understanding lncRNA's biological roles. Computational methods offer an effective alternative to traditional experimental methods for annotating lncRNA subcellular positions.

HMGA1 Plays a Role in Counteracting DNA Damage Induced by BoHV-1 Productive Infection.

Bovine herpesvirus 1 (BoHV-1) productive infection induces the generation of DNA double-strand breaks (DSBs), which may consequently lead to cell apoptosis. In response to DSBs, the DNA damage repair-related protein 53BP1 is recruited to the sites of DSBs, leading to the formation of 53BP1foci, which are crucial for the repair of damaged DNA and maintaining genomic integrity by repairing DSBs. In this study, we discovered that HMGA1 may play a significant role in counteracting virus infection-induced DNA damage, as the siRNA-mediated knockdown of HMGA1 protein expression or inhibition of HMGA1 activity by the chemical inhibitor Netropsin uniformly exacerbates the DNA damage induced by BoHV-1 productive infection.

Pleiotropic Effects of PCSK9 Inhibitors on Cardio-Cerebrovascular Diseases.

Cardiovascular disease (CVD) and ischemic stroke (IS) are the primary causes of mortality worldwide. Hypercholesterolemia has been recognized as an independent risk factor for CVD and IS. Numerous clinical trials have unequivocally demonstrated that reducing levels of low-density lipoprotein cholesterol (LDL-C) significantly mitigates the risk of both cardiac and cerebral vascular events, thereby enhancing patient prognosis.

Intraspecific Chloroplast Genome Genetic Polymorphism of (Xi Junecry) and Its Revelation of a Single Origin in Phylogeny.

: Xi Junecry (), a perennial herb of the Araceae family, is indigenous to Xinxian County, Henan Province, China, and is regarded as a premium variety among similar medicinal materials. However, the lack of comprehensive genetic information on Xi Junecry germplasm resources has constrained the cultivation and identification of high-quality varieties. : In this study, six chloroplast genomes of Xi Junecry were assembled and annotated using high-throughput sequencing.

Genome-Wide Identification and Evolutionary Analysis of Functional Genes in Plant Species.

: BABY BOOM (BBM), a transcription factor from the APETALA2 (AP2) protein family, plays a critical role in somatic embryo induction and apomixis. has now been widely applied to induce apomixis or enhance plant transformation and regeneration efficiency through overexpression or ectopic expression. However, the structural and functional evolutionary history of genes in plants is still not well understood.

Understanding the Causes of Keel Bone Damage and Its Effects on the Welfare of Laying Hens.

Keel bone damage (KBD) is a prominent concern within the realm of the egg-laying industry, exerting substantial impacts on the welfare and productivity of laying hens. This comprehensive review undertakes a detailed exploration of the diverse factors contributing to KBD, such as inadequate calcium sources in the medullary bone, genetic factors, nutritional deficiencies, and physical stressors. The consequences of KBD on production performance, stress and inflammation levels, and the physical and chemical properties of the keel are meticulously examined.

The association between family resilience and psychological well-being during the COVID-19 pandemic: A three-level meta-analysis.

Despite numerous studies observing a positive correlation between family resilience and psychological well-being during the COVID-19 pandemic, the strength of this association varied considerably in previous research. This study aims to obtain reliable estimates for effect sizes and investigate the potential moderators of the association between family resilience and psychological well-being during the COVID-19 pandemic. Seventeen studies (65 effect sizes, 14,511 participants) were reviewed using a systematic literature search and the PRISMA approach.

High-Density Polyethylene Janus Fibrous Membrane with Enhanced Breathability and Moisture Permeability via PDA Assisted Hydrophilic Modification.

Functional fibrous membranes with high mechanical properties are intensively developed for different application fields. In this study, to enhance moisture and air permeability without compromising mechanical strength, a facile float-surface modification strategy is employed to fabricate Janus fibrous membranes with distinct hydrophobicity/hydrophilicity using the high-density polyethylene (HDPE) fibrous membranes. By coating one side of the HDPE fibrous membranes with polydopamine (PDA) and a superhydrophilic polyelectrolyte, the obtained Janus HDPE fibrous membranes demonstrate an excellent water transmission rate (577.

Concurrent preoperative eribulin and radiation for resectable retroperitoneal liposarcoma: a phase 1B study.

Background Management of retroperitoneal liposarcoma (RPLPS) is challenging and recurrence rates remain high despite aggressive surgical resections. Preoperative radiation alone lacks definitive benefit, thus we sought to evaluate combined chemoradiotherapy with the potential to enhance local efficacy of radiation as well as control micrometastatic disease. We assessed the safety and tolerability of preoperative eribulin, a cytotoxic microtubule inhibitor approved for the treatment of advanced liposarcoma, in combination with radiation in patients with RPLPS.

METTL7A improves bovine IVF embryo competence by attenuating oxidative stress.

Unlabelled: In vitro fertilization (IVF) is a widely used assisted reproductive technology to achieve a successful pregnancy. However, the acquisition of oxidative stress in embryo in vitro culture impairs its competence. Here, we demonstrated that a nuclear coding gene, methyltransferase- like protein 7A (METTL7A), improves the developmental potential of bovine embryos.

Efficacy and safety of immune checkpoint inhibitors for EGFR mutated non-small cell lung cancer: a network meta-analysis.

Introduction: Non-small cell lung cancer (NSCLC) constitutes approximately 80-85% of cancer-related fatalities globally, and direct and indirect comparisons of various therapies for NSCLC are lacking. In this study, we aimed to compare the efficacy and safety of immune checkpoint inhibitors (ICIs) in patients with epidermal growth factor receptor (EGFR)-mutated NSCLC.

Methods: The electronic databases were systematically searched from inception until March 18, 2024.

Bithiophene dicarboxylate as an efficient organic anode material for sodium-ion batteries.

In this study, new carboxylates are synthesized for sodium-ion batteries. The bithiophene-based anode material BT demonstrates a high reversible capacity of 201 mA h g and excellent durability. BT retains 99.

Soil fluoride enrichment process and the possible adaptation prevention principle in coal-burning fluorosis area in Southwest China.

Coal-burning fluorosis prevails in southwest China and other provinces. Although clay used as binder of briquettes was proven to cause coal-burning fluorosis, its enrichment processes remain unknown. The soils and rocks on typical geological units were sampled and simulation experiments were performed to detect the forming process of high-fluoride clay.

Sucker rod straightness measurement method based on probability statistics of edge point detection.

Straightness is the basic measurement parameter in machining, and the traditional straightness measurement methods such as light gap method, table method, et al., have extremely low measurement efficiency and cannot achieve online real-time high-precision detection. Our research group has proposed a machine vision online detection based on 10 industrial camera arrays, which can obtain the surface profile straight line of the sucker rod by collecting the edge profile image of the sucker rod and performing morphological transformation.

Efficacy and safety of multi-target tyrosine kinase inhibitor AL2846 combined with gemcitabine in pancreatic cancer.

Pancreatic cancer patients urgently need new treatments, and we explored the efficacy and safety of combination therapy with AL2846 and gemcitabine in pancreatic cancer patients. This was a single-arm, single-center, open-label phase I/IIa study (NCT06278493). The dose-escalation phase was designed to evaluate the maximum tolerated dose (MTD) of AL2846 combined with gemcitabine.

A multi-branch, multi-scale, and multi-view CNN with lightweight temporal attention mechanism for EEG-based motor imagery decoding.

Convolutional neural networks (CNNs) have been widely utilized for decoding motor imagery (MI) from electroencephalogram (EEG) signals. However, extracting discriminative spatial-temporal-spectral features from low signal-to-noise ratio EEG signals remains challenging. This paper proposes MBMSNet , a multi-branch, multi-scale, and multi-view CNN with a lightweight temporal attention mechanism for EEG-Based MI decoding.