Ultra-High-Resolution Photon-Counting Detector CTA of the Head and Neck: Image Quality Assessment and Vascular Kernel Optimization.

Head and neck CTA requires fine detail evaluation, including characterization of potentially very small vessels and intrastent lumens. Blooming artifacts also hinder evaluation. To evaluate image quality of ultra-high-resolution (UHR) photon-counting detector (PCD) CTA of the head and neck and to explore variation of such quality across reconstruction kernels.

Preparation and Application of Two-Dimensional TaC MXene/Gold Nanostar Composite SERS Substrates for Thiram Detection.

Surface-enhanced Raman scattering (SERS) is a novel spectroscopic technique that enables the identification of analytes through analysis of their unique chemical signatures. Its high sensitivity, specificity, and rapid response make it a valuable tool in a range of fields, including biological detection, food safety, and environmental monitoring. However, traditional SERS nanoparticle substrates are susceptible to instability and agglomeration.

Multiple-unit interlocking enhances the single-stranded tiles assembly of DNA nanostructures.

Single-stranded tiles (DNA brick) assembly has provided a simple and modular tool for constructing nanostructures with the potential for numerous applications. However, in this strategy, the short-strand building blocks are susceptible to environmental fluctuations and bring about rapid dissociation during assembly, resulting in instability and prolonged annealing. Thus, developing new strategies which can enhance the stability and accelerate the assembly process of DNA bricks is important.

Risk of pulmonary complications after video-assisted thoracoscopic pulmonary resection in children.

Background: Postoperative pulmonary complications (PPCs) are associated with high mortality and morbidity rates. Children are more susceptible to PPCs owing to smaller functional residual capacity and greater closing volume. Risk factors of PPCs in children undergoing lung resection remain unclear.

A Signal Amplitude-Insensitive Triboelectric Touch Panel with a Significantly Reduced Signal Channel and Deep-Learning-Enhanced Robustness.

The self-powered triboelectric touch panel has garnered considerable research attention due to its potential to reduce system energy consumption and its applications in human-machine interfaces, e-skin, and the Internet of Things. Current methods for achieving triboelectric-based touch positioning in an × detection pixel array typically require signal amplitude comparison across at least + signal channels, thereby limiting lightweight design possibilities. In contrast, our novel "resistor ladder" approach necessitates only 4 signal channels for touch positioning.

Formation of Alloyed CuCoZnSn(S,Se) Absorption Layer and Its Application in Solar Cells.

Partial substitution of cations is crucial for suppressing harmful defects in CuZnSn(S,Se) thin-film solar cells. In this study, based on the mixed -butylammonium and butyrate solution system, the alloyed CuCoZnSn(S,Se) phase can be prepared by substituting Zn with Co, which can suppress harmful defects and optimize the crystallinity of the CuZnSn(S,Se) absorption layer, and improve the photoelectric conversion efficiency (PCE) of devices. By systematic investigation of the impact of Co content on the performance of devices, the optimal substitution amount of Zn with Co is 0.

Caspase-8 in inflammatory diseases: a potential therapeutic target.

Caspase-8, a renowned cysteine-aspartic protease within its enzyme family, initially garnered attention for its regulatory role in extrinsic apoptosis. With advancing research, a growing body of evidence has substantiated its involvement in other cell death processes, such as pyroptosis and necroptosis, as well as its modulatory effects on inflammasomes and proinflammatory cytokines. PANoptosis, an emerging concept of cell death, encompasses pyroptosis, apoptosis, and necroptosis, providing insight into the often overlapping cellular mortality observed during disease progression.

Identification and validation of diagnostic markers related to immunogenic cell death and infiltration of immune cells in diabetic nephropathy.

Introduction: Immunogenic cell death (ICD) is a unique cell death triggered by chemotherapy. However, studies elucidating the potential therapeutic role of ICD and the underlying mechanism in diabetic nephropathy (DN) are limited.

Methods: WGCNA was conducted on the human kidney biopsy data linked to DN, analyzing gene sets associated with ICD.

Bacterial diseases in Siniperca chuatsi: status and therapeutic strategies.

Mandarin fish (Siniperca chuatsi) is a prominent freshwater species with significant economic value in China, while disease poses a major hindrance to the advancement of mandarin fish aquaculture. To date, the understanding of the prevention and management of bacterial disease in mandarin fish remains incomplete. Therefore, there is a need for more comprehensive insights into the preventive and curative strategies to address these bacterial infections.

SARS-CoV-2 nsp13 suppresses hepatitis B virus replication by targeting cccDNA transcription.

Unlabelled: SARS-CoV-2 nonstructural protein 13 (nsp13) has been shown to selectively suppress the transcription of episomal DNA while sparing chromosomal DNA. Hepatitis B Virus (HBV) harbors covalently closed circular DNA (cccDNA), a form of viral episomal DNA found within infected hepatocyte nuclei. The persistence of cccDNA is the major cause of chronic HBV infection.

CdWO Sub-1 nm Nanowires for Visible-Light CO Photoreduction.

Quantum size effect usually causes energy level splitting and band broadening as material size decreases. However, this may change again by the surface adsorbents, doping and defects, which rarely attracts much attention. Herein, CdWO sub-1 nm nanowires (SNWs) with oleylamine adsorption, PO -doping and oxygen defects are synthesized by combining Cd(CHCOO), HPWO (PW) and oleylamine (abbreviated as PO -CdWO-X SNWs).

The Combination of Gastrodin and Gallic Acid Synergistically Attenuates AngII-Induced Apoptosis and Inflammation via Regulation of Sphingolipid Metabolism.

Background: Hypertension (HTN) is closely related to endothelial damage. While tianma (TM) and gouqizi (GQZ) have the potential to be effective in the treatment of HTN in traditional Chinese medicine, their main active ingredients and whether its exert synergistic effects and the underlying mechanisms of synergistic effects are still unclear.

Objective: This study screened the active ingredients of TM and GQZ, investigated the synergistic effects of the active ingredients and explored possible mechanisms.

A comprehensive prediction model of drug-refractory epilepsy based on combined clinical-EEG microstate features.

Background: Epilepsy is a chronic neurological disorder characterized by recurrent seizures that significantly impact patients' quality of life. Identifying predictors is crucial for early intervention.

Objective: Electroencephalography (EEG) microstates effectively describe the resting state activity of the human brain using multichannel EEG.