Dental Bleaching with Phthalocyanine Photosensitizers: Effects on Dentin Color and Collagen Content.

With the increasing demand for tooth bleaching in esthetic dentistry, its safety has been the focus of a comprehensive body of literature. In this context, the aim of the present study was to evaluate the application effects of pentalysine β-carbonylphthalocyanine zinc (ZnPc(Lys))-mediated photodynamic therapy in dentin bleaching and its effects on dentin collagen. We first established a new and reproducible tooth staining model using dentin blocks stained by Orange II and then bleached with ZnPc(Lys) (25 μM) and hydrogen peroxide (10% or 30%).

Expanding the applications of photodynamic therapy-tooth bleaching.

Objectives: The current tooth bleaching materials are associated with adverse effect. Photodynamic method based on a novel photosensitizer alone, without combining with peroxides, is evaluated for tooth bleaching application.

Materials And Methods: Teeth samples were randomly divided into 3 groups with different treatment schemes, including negative control group (group A, physiological saline), experimental group (group B, ZnPc(Lys)), and the positive control group (group C, hydrogen peroxide).