Publications by authors named "Zhoubing Wang"
Background: Fear memory extinction is closely related to insomnia. Repetitive transcranial magnetic stimulation (rTMS) is safe and effective for treating insomnia disorder (ID), and it has been shown to be an efficient method for modulating fear extinction. However, whether rTMS can improve fear extinction memory in ID patients remains to be studied.
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- Insomnia is a common sleep disorder, and this clinical trial investigates the effectiveness of repetitive transcranial magnetic stimulation (rTMS) aimed at the medial prefrontal cortex (mPFC) as a treatment method.
- The study involves 60 patients with insomnia, split into two groups: one receiving real mPFC-rTMS and the other receiving a sham treatment, with interventions conducted over 4 weeks and assessments at various stages.
- The goal is to determine the efficacy of mPFC-rTMS using the Pittsburgh Sleep Quality Index while also exploring related neural mechanisms through fMRI, contributing valuable insights into potential treatments for insomnia.
Background: Phobic fears are common in the general population and among individuals with major depression (MD). We know little about the prevalence, clinical correlates, and structure of phobic fears in Chinese women with MD.
Methods: We assessed 22 phobic fears in 6017 Han Chinese women with MD.
Background: The relationship between age at onset (AAO) and major depression (MD) has been studied in US, European and Chinese populations. However, larger sample studies are needed to replicate and extend earlier findings.
Methods: We re-examined the relationship between AAO and the clinical features of recurrent MD in Han Chinese women by analyzing the phase I (N=1848), phase II (N=4169) and total combined data (N=6017) from the CONVERGE project.
Background: Dysthymia is a form of chronic mild depression that has a complex relationship with major depressive disorder (MDD). Here we investigate the role of environmental risk factors, including stressful life events and parenting style, in patients with both MDD and dysthymia. We ask whether these risk factors act in the same way in MDD with and without dysthymia.
View Article and Find Full Text PDFBackground: A number of clinical features potentially reflect an individual's familial vulnerability to major depression (MD), including early age at onset, recurrence, impairment, episode duration, and the number and pattern of depressive symptoms. However, these results are drawn from studies that have exclusively examined individuals from a European ethnic background. We investigated which clinical features of depressive illness index familial vulnerability in Han Chinese females with MD.
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- In a study comparing Han Chinese women with major depressive disorder (MDD) to matched controls, researchers found that those with MDD reported significantly more stressful life events (SLEs) than those without.
- Of the 16 types of SLEs examined, 14 were notably more common among MDD patients, with rape, physical abuse, and serious neglect being the most strongly linked to the onset of MDD.
- The study highlights the potential psychosocial factors contributing to MDD in Chinese women, though results may not be applicable to males and rely on retrospective accounts of events.