Publications by authors named "Zhou-Shi Yao"

Background: Emerging data suggest that in patients with low prostate-specific antigen (PSA) and high Gleason score, prostate cancer (PCa) is more aggressive and more likely to be related to genomic characteristics of neuroendocrinology. However, the evidence for the advantages of local treatment (LT) for these men is lacking. Hence, we investigated survival in men with low-PSA values and high-grade (Gleason score 8-10) PCa according to the treatment of the primary tumor.

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Rationale: Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD) are progressive neuromuscular disorders caused by mutations in the dystrophin gene. The management of anesthesia in patients with BMD is complicated because they are highly sensitive to the conventional anesthetics such as volatile anesthetics and muscle relaxants. It is reported that anesthesia in patients with DMD is associated with several complications.

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Oxidative stress appears to be a central event responsible for the degeneration of dopaminergic neurons in Parkinson's disease (PD). 1-methyl-4‑phenyl-1,2,3,6-tetrahydropyridine or its toxic metabolite 1‑methyl‑4‑phenylpyridinium (MPP+) are classical widely‑used pharmacological and toxic agents to model PD; they cause the production of reactive oxygen species by inhibiting mitochondrial complex I, leading to DNA oxidative damage and subsequent neuronal death. Previous findings have suggested that proliferating cell nuclear antigen (PCNA), a critical regulatory protein for DNA repair, is involved in dopaminergic neuron damage in the MPP+‑induced PD model.

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Article Synopsis
  • The study examines the role of MMP-7 expression in esophageal cancer (EC) and its relationship with tumor invasion and metastasis, highlighting inconsistent clinicopathological value for EC patients.
  • A meta-analysis of 14 clinical cohort studies involving 935 tumor samples was conducted, revealing a positive correlation between increased MMP-7 expression and higher TNM stages (III-IV) as well as other factors like differentiation and invasion grades, and lymph-node metastasis.
  • Significant associations were particularly noted in studies from China, indicating MMP-7's potential as a marker for EC progression across various stages and characteristics.
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By integrating coherent tracking sensor functionality into a coherent communication receiver, a dual-function receiver with coherent boresight error sensing is developed for tracking in coherent free-space optical communication systems. The sensor principles are analyzed according to optical interference theory, and the boresight error detection algorithm and small signal linear model are derived. Analysis of local-oscillator beam nutation on system performance shows that the best nutation half-angle is 0.

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