A pairwise radiomics algorithm-lesion pair relation estimation model for distinguishing multiple primary lung cancer from intrapulmonary metastasis.

Background: Distinguishing multiple primary lung cancer (MPLC) from intrapulmonary metastasis (IPM) is critical for their disparate treatment strategy and prognosis. This study aimed to establish a non-invasive model to make the differentiation pre-operatively.

Methods: We retrospectively studied 168 patients with multiple lung cancers (307 pairs of lesions) including 118 cases for modeling and internal validation, and 50 cases for independent external validation.

Prognostic value of neutrophil to lymphocyte ratio and platelet counts during chemotherapy in patients with advanced gastric cancer.

Objectives: To investigate the predictive significance of dynamic changes in the neutrophil to lymphocyte ratio (NLR) and platelet counts (PLTs) in patients with advanced gastric cancer (GC) during chemotherapy.

Methods: A total of 259 advanced GC patients receiving chemotherapy were enrolled and grouped by high or low NLR with a cut value of 2.5 and PLT with cut value of 300×10/L.

Correlation Analysis between T790M Status and Clinical Characteristics of Patients with EGFR-sensitive Mutation Advanced NSCLC who Progressed after the First Generation and First-line EGFR-TKIs Administration: A Real-world Exploratory Study.

Aim: The present study is to investigate the association between T790M status and clinical characteristics of patients with EGFR-sensitive advanced non-small cell lung cancer (NSCLC) who progressed the initial epidermal growth factor receptor tyrosine kinase inhibitors (EGFRTKIs) administration.

Methods: A total of 167 patients with EGFR-sensitive mutations advanced NSCLC who had successful genetic tests and progressed the initial EGFR-TKI treatment were included in this study retrospectively. The clinical and demographic characteristics of these patients were collected, which were manifested as pathological type, metastasis location, initial biopsy method, initial genetic test specimens, and baseline gene mutations status.

Tracheoesophageal fistula closure after staged dose-escalated radiotherapy for esophageal squamous cell carcinoma: a case report.

An esophageal fistula can be caused by an esophageal tumor as well as the surgery, radiotherapy (RT), or chemoradiotherapy used to treat the tumor. The most dangerous complications are massive hemoptysis and asphyxia. This report describes a 58-year-old man with a >1-month history of dysphagia and hemoptysis.

Treatment mode and prognosis of esophageal perforation after radiotherapy in patients with esophageal carcinoma.

Objective: Retrospectively analyzed the esophageal carcinoma (EC) patients with esophageal perforation (EP) after radiotherapy to discuss the treatment and prognosis.

Methods: Data of patients with EC who had EP after radiotherapy in Hebei Cancer Hospital were collected from 2001 to 2020 and retrospectively analyzed. All analyses were performed using SPSS Statistics for Windows, version 18.

An Improved Surgical Technique to Increase Neck Width of Elastase-Induced Aneurysm Model in Rabbits: A Prospective Study.

Background: Rabbit elastase-induced aneurysms have widely been used to test various endovascular materials over the past two decades. However, wide-necked aneurysms cannot be stably constructed.

Objective: The purpose of the study was to increase the neck width of the elastase-induced aneurysm model in rabbits an improved surgical technique with two temporary clips.

Survivors of COVID-19 exhibit altered amplitudes of low frequency fluctuation in the brain: a resting-state functional magnetic resonance imaging study at 1-year follow-up.

Although some short-term follow-up studies have found that individuals recovering from coronavirus disease 2019 (COVID-19) exhibit anxiety, depression, and altered brain microstructure, their long-term physical problems, neuropsychiatric sequelae, and changes in brain function remain unknown. This observational cohort study collected 1-year follow-up data from 22 patients who had been hospitalized with COVID-19 (8 males and 11 females, aged 54.2 ± 8.

Pilot Study of CT-Based Radiomics Model for Early Evaluation of Response to Immunotherapy in Patients With Metastatic Melanoma.

Determine the performance of a computed tomography (CT) -based radiomics model in predicting early response to immunotherapy in patients with metastatic melanoma. This retrospective study examined 50 patients with metastatic melanoma who received immunotherapy treatment in our hospital with an anti-programmed cell death-1 (PD-1) agent or an inhibitor of cytotoxic T lymphocyte antigen-4 (CTLA-4). Thirty-four patients who received an anti-PD-1 agent were in the training sample and 16 patients who received a CTLA-4 inhibitor were in the validation sample.

The routine cutoff displacement of 2 mm may not reliably reflect the stability of paediatric lateral humeral condyle fractures.

Introduction: Lateral humeral condyle fracture is one of the most common fractures in children. However, the prediction of the stability of the fracture with a cutoff displacement of 2 mm remains controversial. The aim of this study was to evaluate the reliability of the routine cutoff displacement of 2 mm in predicting the stability of paediatric lateral humeral condyle fractures.

[Effect of sowing dates on cotton yield, fiber quality, and uptake and utilization of nutrients in Inner Mongolia west desert area, China].

Field experiments were conducted in 2014 and 2015 at the "Inner Mongolia cotton comprehensive test station" (39°27' N, 105°39' E) in Alxa Left Banner of Alxa League in Inner Mongolia. By using cotton cultivar CCRI-50 as material and the "6 cotton rows with 3 dripping pipes under a plastic film mulching" plantation pattern, different sowing dates (20-Apr, 30-Apr and 10-May) were set to study the effect of sowing dates on cotton yield, fiber quality and nutrient uptake and utilization. The results showed that as the sowing date delayed, the development of cotton plant was delayed, the yield forming stage shortened, and the mean daily temperature of boll deve-lopment reduced, but the harvesting density increased.

[Trends and temporal-spatial distribution of fiber quality in the national cotton variety regional trials.].

This study applied a grey predicting model to predict the trend of cotton fiber quality for next 5 and 10 years in the Yellow River Valley (YeRV), the Yangtze River Valley (YaRV) and the Northwest Inland Region (NWIR) based on the data set from the fiber quality traits of candidate cultivars in National Cotton Variety Regional Trials during 2005-2014. The temporal and spatial distributions of cotton trails in the three major cotton producing regions were analyzed. The results showed that the overall fiber quality of the Regional Cotton Variety Trials was improved during 2005-2014.

Effects of Soil Salinity on the Expression of Bt Toxin (Cry1Ac) and the Control Efficiency of Helicoverpa armigera in Field-Grown Transgenic Bt Cotton.

An increasing area of transgenic Bacillus thuringiensis (Bt) cotton is being planted in saline-alkaline soil in China. The Bt protein level in transgenic cotton plants and its control efficiency can be affected by abiotic stress, including high temperature, water deficiency and other factors. However, how soil salinity affects the expression of Bt protein, thus influencing the control efficiency of Bt cotton against the cotton bollworm (CBW) Helicoverpa armigera (Hübner) in the field, is poorly understood.

Support Vector Machines Model of Computed Tomography for Assessing Lymph Node Metastasis in Esophageal Cancer with Neoadjuvant Chemotherapy.

Objective: The aim of this study was to diagnose lymph node metastasis of esophageal cancer by support vector machines model based on computed tomography.

Materials And Methods: A total of 131 esophageal cancer patients with preoperative chemotherapy and radical surgery were included. Various indicators (tumor thickness, tumor length, tumor CT value, total number of lymph nodes, and long axis and short axis sizes of largest lymph node) on CT images before and after neoadjuvant chemotherapy were recorded.

How Integrated Management Strategies Promote Protein Quality of Cotton Embryos: High Levels of Soil Available N, N Assimilation and Protein Accumulation Rate.

Cottonseed is widely used as a source of ruminant feed and for industrial purposes. Therefore, there is a tremendous need to improve the nutritional value of cotton embryos. In this study, a conventional management (CM) and two integrated cotton management strategies (IMS1, IMS2) were performed at two soil fertility levels to study the relationships among soil N, N assimilation, embryonic protein accumulation and protein quality.

[Hyperspectral parameters and prediction model of soil moisture in coastal saline].

Based on the data of soil moisture content and indoor soil surface spectral reflectance from five sampling sites of coastal saline soil, this paper analyzed the relationship between soil moisture content and soil spectrum in wavelength 350-2500 nm. We determined spectral parameters under ratio spectral index (RSI), normalized difference spectral index (NDSI) and difference spectral index (DI), and established the quantitative model of soil moisture content. The results showed significant negative correlation between spectral reflectance and soil moisture content, and the maximum negative correlation was near 1930 nm (r=0.

The Distribution and Host Shifts of Cotton-Melon Aphids in Northern China.

Aphis gossypii Glover (Hemiptera: Aphididae) is a serious pest of cotton in northern China. A microsatellite analysis was used to characterize the genetic structure of A. gossypii populations from different geographic, host plant, and seasonal populations in 2014.

[Key time window of fiber quality formation in response to short-term higher temperature stress].

By taking two cotton cultivars with different temperature-sensitivity (Sumian 15, temperature-sensitive cultivar and Kemian 1, temperature-insensitive cultivar) as materials, an experiment with two temperature regimes (high temperature: 34 °C [38/30 °C], HT and control: 26 °C [30/22 °C], CK) were set in climate chamber to study the change of key matters in different genotypes cotton in response to high temperature and their relationships with fiber quality. The results showed that as treated in the 34.0 °C high-temperature regime for 5 days at different DPA (days past anthesis), significant change in fiber quality was observed in the temperature-sensitive cultivar Sumian 15.

Salvage radiotherapy in patients with local recurrent esophageal cancer after radical radiochemotherapy.

Purpose: The aim of this study was to evaluate the salvage radiotherapy outcome in patients with local recurrent esophageal cancer after radical radiochemotherapy (RCT).

Methods: A total of 114 patients with local recurrent esophageal squamous cell carcinoma after initial radical RCT were retrospectively analyzed. Fifty-five (55) patients belonged to the salvage radiotherapy group (SR group) and 59 patients to the non-salvage radiotherapy group (NSR group).