Changes in species' habitats provide important insights into the effects of climate change. , a critically endangered species endemic to karst ecosystems, has a highly restricted distribution and is a key biological resource. Despite its ecological importance, the factors influencing its habitat suitability and distribution remain poorly understood.
View Article and Find Full Text PDFAn elastocaloric thermal battery based on generative learning-designed phase-change alloys is developed to facilitate the efficient recycling of low-temperature waste heat. This battery stores thermal energy as latent heat in a phase-change alloy and releases it on demand through applied stress at ambient temperature. Alloy compositions and corresponding processing parameters, tailored to desired transformation characteristics, are efficiently discovered through a generative learning-enabled inverse design framework, which converts the hand-drawn target heat flow curve into tangible compositional and processing designs.
View Article and Find Full Text PDFThe current study was to explore the prevalence and risk factors elements of pre-frailty and frailty among patients undergoing hemodialysis (HD) in central China. A cross-sectional, multi-institutional investigation was conducted. From March to May 2024, using the convenience sampling method, a total of 408 HD patients from four hospitals in Xiangyang, China, were recruited for this study.
View Article and Find Full Text PDFPancreatic development is a complex process vital for maintaining metabolic balance, requiring intricate interactions among different cell types and signaling pathways. Fibroblast growth factor receptors 2b (FGFR2b)-ligands signaling from adjacent mesenchymal cells is crucial in initiating pancreatic development and differentiating exocrine and endocrine cells through a paracrine mechanism. However, the precise critical time window that affects pancreatic development remains unclear.
View Article and Find Full Text PDFObjective: The aim of the study was to investigate the distribution and association between human papillomavirus (HPV) genotypes and integration as well as their correlation with cervical lesions.
Methods: Two hundred seven patients diagnosed with high-grade vaginal intraepithelial neoplasia (HG-VaIN) were recruited from the Women's Hospital School of Medicine Zhejiang University between 2015 and 2021 and assayed for HPV genotyping. HPV integration sequencing analysis was conducted using tissues from 53 patients with HG-VaIN and 4 patients with invasive vaginal carcinoma (IVC), along with paired cervical lesion specimens.
Objective: Added sugars have been associated with a variety of adverse health consequences, but their relationship with osteoarthritis is unclear. This study aimed to demonstrate the association between added sugars and osteoarthritis.
Methods: We used the National Health and Nutrition Examination Survey (NHANES) database from 2007 to 2018 to explore the association between added sugars and osteoarthritis.
Elastic materials that store and release elastic energy play pivotal roles in both macro and micro mechanical systems. Uniting high elastic energy density and efficiency is crucial for emerging technologies such as artificial muscles, hopping robots, and unmanned aerial vehicle catapults, yet it remains a significant challenge. Here, a nanocrystalline structure embedded with elliptical martensite nanodomains in ferroelastic alloys was utilized to enable high yield strength, large recoverable strain, and low energy dissipation simultaneously.
View Article and Find Full Text PDFObjective: Poly (ADP-ribose) polymerase (PARP) inhibitors such as olaparib and niraparib have shown promise in extending progression-free survival (PFS) in patients with platinum-sensitive recurrent (PSR) epithelial ovarian cancer. In this retrospective study, we aimed to present our own data on the effect of PARP inhibitors on PFS in recurrent epithelial ovarian cancer.
Methods: 82 patients diagnosed with PSR epithelial ovarian, tubal, or primary peritoneal cancer between May 2017 and September 2023 were initially enrolled from our hospital.
Coating high concentrations of copper (Cu) on the inner wall of containers can efficiently inhibit root entanglement of container-grown seedlings. However, how the protective and defensive responses of roots maintain root structure and function during Cu-root pruning is still unclear. Here, Duranta erecta L.
View Article and Find Full Text PDFShape memory alloys (SMAs) with large latent heat absorbed/released during phase transformation at elevated temperatures benefit their potential application on thermal energy storage (TES) in high temperature environment like power plants, etc. The desired alloys can be designed quickly by searching the vast component space of doped NiTi-based SMAs via data-driven method, while be challenging with the noisy experimental data. A noise-aware active learning strategy is proposed to accelerate the design of SMAs with large latent heat at elevated phase transformation temperatures based on noisy data.
View Article and Find Full Text PDFUnlabelled: species are among the most common free-living amoeba and ubiquitous protozoa, mainly distributed in water and soil, and cause keratitis (AK) and severe visual impairment in patients. Although several studies have reported genomic characteristics of , limited sample sizes and sources have resulted in an incomplete understanding of the genetic diversity of from different sources. While endosymbionts exert a significant influence on the phenotypes of , including pathogenicity, virulence, and drug resistance, the species diversity and functional characterization remain largely unexplored.
View Article and Find Full Text PDFAim And Objectives: To investigate the prevalence of dysphagia in patients with COPD, identify the risk factors for dysphagia, develop a visual clinical prediction model and quantitatively predict the probability of developing dysphagia.
Background: Patients with COPD are at high risk of dysphagia, which is strongly linked to the acute exacerbation of their condition. The use of effective tools to predict its risk may contribute to the early identification and treatment of dysphagia in patients with COPD.
Although colorectal cancer (CRC) remains the second leading cause of cancer-related death in the United States, the overall incidence and mortality from the disease have declined in recent decades. In contrast, there has been a steady increase in the incidence of CRC in individuals under 50 years of age. Hereditary syndromes contribute disproportionately to early onset CRC (EOCRC).
View Article and Find Full Text PDFBackground: Remimazolam is a novel ultra-short-acting benzodiazepine sedative that has the potential to be an alternative for procedural sedation due to its rapid sedation and recovery, no accumulation effect, stable hemodynamics, minimal respiratory depression, anterograde amnesia effect, and specific antagonist. Here, we aimed to compare the safety and efficacy of remimazolam with dexmedetomidine for awake tracheal intubation by flexible bronchoscopy (ATI-FB).
Methods: Ninety patients scheduled for ATI-FB were randomly divided into three groups, each consisting of 30 cases: dexmedetomidine 0.
Background: Mechanical ventilation (MV) sustains life in critically ill patients by providing adequate alveolar ventilation. However, prolonged MV could induce inspiratory muscle atrophy known as ventilator-induced diaphragmatic dysfunction (VIDD). Insulin-like growth factor () has been proven to play crucial roles in regulating skeletal muscle size and function.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2023
Selection of stable housekeeping genes (HKGs) is very important for accurate calculation of relative expression levels of target genes by quantitative real-time polymerase chain reaction (qRT-PCR). At present, the appropriate HKGs have not been identified in placental tissues throughout the pregnancy of the goat. In our study, 20 HKGs were tentatively selected from RNA-seq data and previous reports.
View Article and Find Full Text PDFThis work addresses the quasi-synchronization of delay master-slave BAM neural networks. To improve the utilization of channel bandwidth, a dynamic event-triggered impulsive mechanism is employed, in which data is transmitted only when a preset event-triggered mechanism or a forced impulse interval is satisfied. In addition, to guarantee the reliability of information transmission, a reliable redundant channel for BAM neural networks is adopted, whose transmission scheduling strategy is designed on the basis of the packet dropouts rate of the main communication channels.
View Article and Find Full Text PDFNeuro Endocrinol Lett
September 2023
Purpose: This study was aimed to investigate the influence of carotid hemodynamics in common carotid artery (CCA) and internal carotid artery (ICA) on carotid plaque location.
Methods: A total of 4444 participants from Anhui Maanshan People's Hospital were selected from December 2013 to December 2018. Doppler ultrasound was used to measure the location of carotid plaque.
Nanomaterials (Basel)
September 2023
Lithium-sulfur (Li-S) batteries are regarded as highly promising energy storage devices due to their high theoretical specific capacity and high energy density. Nevertheless, the commercial application of Li-S batteries is still restricted by poor electrochemical performance. Herein, beaded nanofibers (BNFs) consisting of carbon and CoSe nanoparticles (CoSe/C BNFs) were prepared by electrospinning combined with carbonization and selenization.
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