Publications by authors named "Zhou Yumei"

Changes in species' habitats provide important insights into the effects of climate change. , a critically endangered species endemic to karst ecosystems, has a highly restricted distribution and is a key biological resource. Despite its ecological importance, the factors influencing its habitat suitability and distribution remain poorly understood.

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An elastocaloric thermal battery based on generative learning-designed phase-change alloys is developed to facilitate the efficient recycling of low-temperature waste heat. This battery stores thermal energy as latent heat in a phase-change alloy and releases it on demand through applied stress at ambient temperature. Alloy compositions and corresponding processing parameters, tailored to desired transformation characteristics, are efficiently discovered through a generative learning-enabled inverse design framework, which converts the hand-drawn target heat flow curve into tangible compositional and processing designs.

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The current study was to explore the prevalence and risk factors elements of pre-frailty and frailty among patients undergoing hemodialysis (HD) in central China. A cross-sectional, multi-institutional investigation was conducted. From March to May 2024, using the convenience sampling method, a total of 408 HD patients from four hospitals in Xiangyang, China, were recruited for this study.

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Pancreatic development is a complex process vital for maintaining metabolic balance, requiring intricate interactions among different cell types and signaling pathways. Fibroblast growth factor receptors 2b (FGFR2b)-ligands signaling from adjacent mesenchymal cells is crucial in initiating pancreatic development and differentiating exocrine and endocrine cells through a paracrine mechanism. However, the precise critical time window that affects pancreatic development remains unclear.

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Objective: The aim of the study was to investigate the distribution and association between human papillomavirus (HPV) genotypes and integration as well as their correlation with cervical lesions.

Methods: Two hundred seven patients diagnosed with high-grade vaginal intraepithelial neoplasia (HG-VaIN) were recruited from the Women's Hospital School of Medicine Zhejiang University between 2015 and 2021 and assayed for HPV genotyping. HPV integration sequencing analysis was conducted using tissues from 53 patients with HG-VaIN and 4 patients with invasive vaginal carcinoma (IVC), along with paired cervical lesion specimens.

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Objective: Added sugars have been associated with a variety of adverse health consequences, but their relationship with osteoarthritis is unclear. This study aimed to demonstrate the association between added sugars and osteoarthritis.

Methods: We used the National Health and Nutrition Examination Survey (NHANES) database from 2007 to 2018 to explore the association between added sugars and osteoarthritis.

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Elastic materials that store and release elastic energy play pivotal roles in both macro and micro mechanical systems. Uniting high elastic energy density and efficiency is crucial for emerging technologies such as artificial muscles, hopping robots, and unmanned aerial vehicle catapults, yet it remains a significant challenge. Here, a nanocrystalline structure embedded with elliptical martensite nanodomains in ferroelastic alloys was utilized to enable high yield strength, large recoverable strain, and low energy dissipation simultaneously.

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Objective: Poly (ADP-ribose) polymerase (PARP) inhibitors such as olaparib and niraparib have shown promise in extending progression-free survival (PFS) in patients with platinum-sensitive recurrent (PSR) epithelial ovarian cancer. In this retrospective study, we aimed to present our own data on the effect of PARP inhibitors on PFS in recurrent epithelial ovarian cancer.

Methods: 82 patients diagnosed with PSR epithelial ovarian, tubal, or primary peritoneal cancer between May 2017 and September 2023 were initially enrolled from our hospital.

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Article Synopsis
  • Archived tissues, particularly frozen and FFPE samples, are valuable for high-definition genomics aimed at personalized cancer treatment, but face challenges like low cell yields and DNA quality issues due to degradation and contamination.
  • Recent advancements in single cell DNA sequencing (scDNA-seq) allow for better study of tumor heterogeneity and subclonal populations, essential for understanding tumor development and resistance to therapies.
  • The research presented optimized methods for isolating intact nuclei from fresh frozen and FFPE tissues, validated through a sequencing panel, which could enhance the utility of these archived samples in cancer research and clinical applications.
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Coating high concentrations of copper (Cu) on the inner wall of containers can efficiently inhibit root entanglement of container-grown seedlings. However, how the protective and defensive responses of roots maintain root structure and function during Cu-root pruning is still unclear. Here, Duranta erecta L.

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Shape memory alloys (SMAs) with large latent heat absorbed/released during phase transformation at elevated temperatures benefit their potential application on thermal energy storage (TES) in high temperature environment like power plants, etc. The desired alloys can be designed quickly by searching the vast component space of doped NiTi-based SMAs via data-driven method, while be challenging with the noisy experimental data. A noise-aware active learning strategy is proposed to accelerate the design of SMAs with large latent heat at elevated phase transformation temperatures based on noisy data.

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Unlabelled: species are among the most common free-living amoeba and ubiquitous protozoa, mainly distributed in water and soil, and cause keratitis (AK) and severe visual impairment in patients. Although several studies have reported genomic characteristics of , limited sample sizes and sources have resulted in an incomplete understanding of the genetic diversity of from different sources. While endosymbionts exert a significant influence on the phenotypes of , including pathogenicity, virulence, and drug resistance, the species diversity and functional characterization remain largely unexplored.

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Aim And Objectives: To investigate the prevalence of dysphagia in patients with COPD, identify the risk factors for dysphagia, develop a visual clinical prediction model and quantitatively predict the probability of developing dysphagia.

Background: Patients with COPD are at high risk of dysphagia, which is strongly linked to the acute exacerbation of their condition. The use of effective tools to predict its risk may contribute to the early identification and treatment of dysphagia in patients with COPD.

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Although colorectal cancer (CRC) remains the second leading cause of cancer-related death in the United States, the overall incidence and mortality from the disease have declined in recent decades. In contrast, there has been a steady increase in the incidence of CRC in individuals under 50 years of age. Hereditary syndromes contribute disproportionately to early onset CRC (EOCRC).

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Article Synopsis
  • This study focuses on translating the Toxic Leadership Behaviors of Nurse Managers (ToxBH-NM) scale into Chinese and evaluates its effectiveness among Chinese nurses.
  • Data was gathered from a survey of 1,195 nurses using statistical methods like exploratory and confirmatory factor analyses to test the scale's validity and reliability.
  • Findings indicate that the Chinese version of the scale, C-ToxBH-NM, is a reliable and valid tool for assessing toxic leadership behaviors in nursing management, with strong internal consistency and high correlation coefficients.
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Background: Remimazolam is a novel ultra-short-acting benzodiazepine sedative that has the potential to be an alternative for procedural sedation due to its rapid sedation and recovery, no accumulation effect, stable hemodynamics, minimal respiratory depression, anterograde amnesia effect, and specific antagonist. Here, we aimed to compare the safety and efficacy of remimazolam with dexmedetomidine for awake tracheal intubation by flexible bronchoscopy (ATI-FB).

Methods: Ninety patients scheduled for ATI-FB were randomly divided into three groups, each consisting of 30 cases: dexmedetomidine 0.

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Article Synopsis
  • Metastatic castration-resistant prostate cancer (mCRPC) is a severe form of cancer that often leads to poor patient outcomes, prompting the need for better treatment options.
  • Researchers developed and characterized three new patient-derived tumor xenograft (PDTX) models to explore the effectiveness of combining CDK4/6 inhibitors with AKT inhibitors, using 3D spheroids to study drug resistance patterns.
  • Findings indicated that the combination therapy showed promising results in overcoming resistance to single-agent treatments, which supports future clinical trials for mCRPC patients with specific genetic profiles.
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Background: Mechanical ventilation (MV) sustains life in critically ill patients by providing adequate alveolar ventilation. However, prolonged MV could induce inspiratory muscle atrophy known as ventilator-induced diaphragmatic dysfunction (VIDD). Insulin-like growth factor () has been proven to play crucial roles in regulating skeletal muscle size and function.

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  • The study investigates the potential of gut microbiota as predictive biomarkers for patients with postpartum depressive disorder (PPD) undergoing acupuncture treatment.
  • About 79 PPD patients were analyzed, with 55 receiving acupuncture and 24 not receiving any treatment; nearly half of those treated showed a positive response.
  • Results indicated that certain gut microbiota species were more prevalent in acupuncture responders, suggesting they could help predict treatment efficacy, but further research is necessary for validation.
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Article Synopsis
  • The study investigates the connection between immune responses and the effectiveness of acupuncture in treating postpartum depression (PPD), particularly focusing on inflammatory cytokine levels.
  • Among the 121 women with PPD, significant reductions in depression scores were observed after 8 weeks of acupuncture, yet changes in cytokine levels did not significantly differ between those who responded well to treatment and those who did not.
  • Results indicate that responders showed lower levels of certain inflammatory cytokines like IL-6 and IL-10, while non-responders had higher levels of pro-inflammatory cytokines, suggesting acupuncture may help alleviate PPD by modulating the body's inflammatory response.
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Selection of stable housekeeping genes (HKGs) is very important for accurate calculation of relative expression levels of target genes by quantitative real-time polymerase chain reaction (qRT-PCR). At present, the appropriate HKGs have not been identified in placental tissues throughout the pregnancy of the goat. In our study, 20 HKGs were tentatively selected from RNA-seq data and previous reports.

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This work addresses the quasi-synchronization of delay master-slave BAM neural networks. To improve the utilization of channel bandwidth, a dynamic event-triggered impulsive mechanism is employed, in which data is transmitted only when a preset event-triggered mechanism or a forced impulse interval is satisfied. In addition, to guarantee the reliability of information transmission, a reliable redundant channel for BAM neural networks is adopted, whose transmission scheduling strategy is designed on the basis of the packet dropouts rate of the main communication channels.

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Purpose: This study was aimed to investigate the influence of carotid hemodynamics in common carotid artery (CCA) and internal carotid artery (ICA) on carotid plaque location.

Methods: A total of 4444 participants from Anhui Maanshan People's Hospital were selected from December 2013 to December 2018. Doppler ultrasound was used to measure the location of carotid plaque.

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Lithium-sulfur (Li-S) batteries are regarded as highly promising energy storage devices due to their high theoretical specific capacity and high energy density. Nevertheless, the commercial application of Li-S batteries is still restricted by poor electrochemical performance. Herein, beaded nanofibers (BNFs) consisting of carbon and CoSe nanoparticles (CoSe/C BNFs) were prepared by electrospinning combined with carbonization and selenization.

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