[Preparation of multi-layer compound microcapsules and their application in self-healing of concrete cracks].

Concrete is widely used in building construction, civil engineering, roads, bridges, etc., but concrete cracking remains a major issue in the engineering industry. To develop an effective and feasible concrete repair technology, this study combined microbial and microencapsulation technologies to prepare a multi-layer compound microcapsule using the piercing method.

Diagnostic accuracy of two-dimensional shear wave elastography and point shear wave elastography in identifying different stages of liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease: A meta-analysis.

To assess the diagnostic accuracy of two-dimensional shear wave elastography (2-D SWE) and point shear wave elastography (pSWE) in detecting liver fibrosis stages in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), a comprehensive search was conducted across four databases up to February 9, 2024. A bivariate random-effects model was used to analyze the diagnostic accuracy of the methods. After screening, 13 studies involving pSWE included 1527 patients, while nine studies involving 2-D SWE included 1088 patients.

Epidemiological and molecular characterization of investigation of Mycoplasma gallisepticum of goose origin in Guangdong (China).

The Guangdong region is the largest goose farming area in China, which has experience significant economic losse due to the epidemic of Mycoplasma gallisepticum (MG) infection in geese. This study addresses the critical gap in epidemiological data on the prevalence of MG infection in geese, which seriously hinders the diagnosis and treatment. We collected respiratory system samples from geese displaying respiratory symptoms, isolated and identified Mycoplasma species, and confirmed MG presence through PCR.

P300/RNA polymerase II mediates induction of the teleost viral RNA sensor MDA5 through the interferon regulatory factor IRF11.

Melanoma differentiation-associated gene 5 (MDA5) initiates type I interferon (IFN) production by detecting cytosolic viral RNA. Mammalian MDA5 is an IFN-inducible gene and controlled by IFN regulatory factor 1 (IRF1). Teleost MDA5 also induces type I IFN production in response to viruses, yet its regulation remains largely unexplored.

Electrochemical Ammonia Synthesis: The Energy Efficiency Challenge.

We discuss the challenges associated with achieving high energy efficiency in electrochemical ammonia synthesis at near-ambient conditions. The current Li-mediated process has a theoretical maximum energy efficiency of ∼28%, since Li deposition gives rise to a very large effective overpotential. As a starting point toward finding electrocatalysts with lower effective overpotentials, we show that one reason why Li and alkaline earth metals work as N reduction electrocatalysts at ambient conditions is that the thermal elemental processes, N dissociation and NH desorption, are both facile at room temperature for these metals.

Whole genome sequencing and analysis of a goose-derived in Guangdong Province, China.

Introduction: (MG) infection is a primary cause of chronic respiratory disease in poultry, threatening the economic viability of China's goose-farming industry. This study investigated the pathogenicity and drug resistance of an MG strain isolated from geese and whole-genome sequenced the strain.

Material And Methods: A strain designated MG-GD01/22 was isolated from the air-sac tissues of five geese with chronic respiratory disease on a Guangdong goose farm.

Squeeze pumping of lipids and insecticides by ABCH transporter.

ATP-binding cassette (ABC) transporter subfamily H is only identified in arthropods and zebrafish. It transports lipids and is related to insecticide resistance. However, the precise mechanisms of its functions remain elusive.

Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking.

Tomato (Solanum lycopersicum L.), one of the most widely grown vegetable crops in the world, faces cracking problems before and after harvest. Fruit cracking reduces the commercial value and seriously affects the economic performance of the fruits by affecting the appearance and quality of the fruit.

Dynamic Response Mechanism of Bedding Slopes with Alternatively Distributed Soft and Hard Rock Layers Under Different Seismic Excitation Directions: Insights from Numerical Simulations.

The issue of slope stability in earthquakes has become increasingly prominent with the construction of many infrastructure projects such as highways, bridges, and tunnels. To explore the dynamic response characteristics of bedding rock slopes in an earthquake, the three-dimensional dynamic finite-difference method (TDD-FDM) in this study is used to establish simplified rock slope models, taking a bedding rock slope with alternatively distributed soft and hard rock layers in Yunnan, China as a prototype. The dynamic response mechanism of layered rock slopes containing different thicknesses, locations, and quantities of soft rock layers was studied under different excitation directions of seismic waves.

Assessment of external occupational exposure of radiation workers in Jiangsu Province, 2019-2022.

This article analyzes the external occupational radiation exposure distribution and trends among radiation workers in Jiangsu Province. The results show that the total annual collective effective dose for radiation workers in Jiangsu Province from 2019 to 2022 was 24.82 person·Sv, with an average annual effective dose of 0.

Potential causal associations between perfluoroalkyl substances exposure and adverse pregnancy outcomes: A bidirectional two-sample mendelian randomization study.

Maternal exposure to per- and polyfluoroalkyl substances (PFASs) has been linked to adverse pregnancy outcomes (APOs). Nonetheless, the genetic causality underlying this association remains unknown. This research employed a bidirectional two-sample Mendelian randomization (MR) to investigate the potential causal associations between PFASs exposure and APOs risk.

Family Medicine Clerkship Directors' Remediation of Faculty With Mistreatment Concerns: Results From a CERA Clerkship Directors Survey.

Introduction: Little is known about how frequently family medicine (FM) clerkship directors remediate faculty with student mistreatment concerns and their comfort level in performing the remediations. In this exploratory study, we investigated factors associated with the number of faculty remediated for student mistreatment concerns by FM clerkship directors and the comfort level of FM clerkship directors in remediating these faculty.

Methods: Data were collected as part of the 2022 Council of Academic Family Medicine Educational Research Alliance (CERA) survey of FM clerkship directors.

Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling.

Objectives: Osteoporosis is a significant public health concern due to its association with fragility fractures. Despite experiencing such fractures, many patients remain at high risk of future fractures due to inadequate management and treatment of their underlying osteoporosis. This research presents a comprehensive intervention to enhance osteoporosis management in patients with fragility fractures.

Diagnosis of schizophrenia by integrated saccade scores and associations with psychiatric symptoms, and functioning.

Eye movement as a neurobiological biomarker of schizophrenia. We aim to estimate diagnostic accuracy of integrated pro/antisaccade eye movement measurements to discriminate between healthy individuals and schizophrenic patients. We compared the eye movement performance of 85 healthy individuals and 116 schizophrenia-stable patients during prosaccade and antisaccade tasks.

Dynamic sequential cross-sectional scanning increases detection rate of congenital heart disease in sonographers: a prenatal ultrasound training program.

Background: Prenatal ultrasound is the preferred modality for diagnosing fetal congenital heart disease. Given issues of physician proficiency and hospital distribution, we propose a dynamic sequential cross-sectional scanning (SCS) to explore the feasibility of cardiac screening by sonographers with less than 5 years of experience in ultrasound.

Materials And Methods: Twenty residents were randomly divided into two groups, receiving training in the American Institute of Ultrasound in Medicine (AIUM) fetal echocardiography and the SCS method.

Comparative analyses of bacterial contamination and microbiome of broiler carcasses in wet market and industrial processing environments.

The slaughtering environment is crucial for the food hygiene and safety of poultry products. Despite the global dominance of industrial processing, live bird slaughtering in wet markets persists due to cultural, religious, and economic reasons. This study aims to reveal the correlation between hygiene scales in wet markets and bacterial contamination levels on broiler carcasses, with a particular focus on pathobiont transmission risks and microbiome characteristics.

Downregulation of chemokine (C‑C motif) ligand 5 induced by a novel 8‑hydroxyquinoline derivative (91b1) suppresses tumor invasiveness in esophageal carcinoma.

Esophageal squamous cell carcinoma (ESCC) is a particularly aggressive form of cancer with high mortality. In the present study, a novel 8‑hydroxyquinoline derivative (91b1) was investigated for its anticancer activities in ESCC along with its associated mechanisms. The cytotoxic effect of 91b1 were evaluated across five ESCC cell lines using MTS assay, with cisplatin serving as a comparative standard.

Biocontrol Potential of Bacillus strains against soybean cyst nematode (Heterodera glycines) and for promotion of soybean growth.

The soybean cyst nematode (SCN, Heterodera glycines) is the most yield-limiting pathogen in soybeans worldwide. Using chemical pesticides to control this disease is harmful to human and environment. It is urgent to develop environment-friendly nematicides.

Association between Multi-Domain Lifestyle and Objective Cognitive Impairment in Elderly People with SCD and MCI in Chinese Communities.

Objectives: Controlling the lifestyle associated with dementia risk can delay the process of cognitive decline. Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are early states in the development of dementia and are also the window period for early intervention in dementia. The purpose of this study was to explore the association between multi-domain lifestyle and objective cognitive impairment in elderly people with SCD and MCI in Chinese communities and to provide reference for effective implementation of precise health management measures to reduce the risk of dementia.