Persistent Exciton Dressed by Weak Polaronic Effect in Rigid and Harmonic Lattice Dion-Jacobson 2D Perovskites.

The emerging two-dimensional (2D) Dion-Jacobson (DJ) perovskites with bidentate ligands have attracted significant attention due to enhanced structural stability compared with conventional Ruddlesden-Popper (RP) perovskites with monodentate ligands linked by van der Waals interactions. However, how the pure chemical bond lattice interacts with excited state excitons and its impact on the exciton nature and dynamics in 2D DJ-perovskites, particularly in comparison to RP-perovskites, remains unexplored. Herein, by a combined spectroscopy study on excitonic and structural dynamics, we reveal a persistent exciton dressed by a weak polaronic effect in DJ-perovskite due to their rigid and harmonic lattice, in striking contrast to significantly screened exciton polaron observed in RP-perovskites.

Robust excitonic light emission in 2D tin halide perovskites by weak excited state polaronic effect.

2D perovskites hold immense promise in optoelectronics due to their strongly bound electron-hole pairs (i.e., excitons).

Helicity-Resolved Vibrational Coupling in Twist WS/WSe Heterostructures.

Helicity-resolved Raman spectra can provide an intricate view into lattice structural details. Through the analysis of peak positions, intensities, and circular polarized Raman signals, a wealth of information about chiral structure arrangement within the moiré superlattice, interlayer interaction strength, polarizability change in chemical bond, and beyond can be unveiled. However, the relationship between the circular polarization of high-frequency Raman and twist angle is still not clear.

Robust and Efficient Out-of-Plane Exciton Transport in Two-Dimensional Perovskites via Ultrafast Förster Energy Transfer.

Two-dimensional (2D) perovskites, comprising inorganic semiconductor layers separated by organic spacers, hold promise for light harvesting and optoelectronic applications. Exciton transport in these materials is pivotal for device performance, often necessitating deliberate alignment of the inorganic layers with respect to the contacting layers to facilitate exciton transport. While much attention has focused on in-plane exciton transport, little has been paid to out-of-plane interlayer transport, which presumably is sluggish and unfavorable.

Revealing the Optical Transition Properties of Interlayer Excitons in Defective WS/WSe Heterobilayers.

Manipulation of physical properties in multidimensional tunable moiré superlattice systems is a key focus in nanophotonics, especially for interlayer excitons (IXs) in two-dimensional materials. However, the impact of defects on IXs remains unclear. Here, we thoroughly study the optical properties of WS/WSe heterobilayers with varying defect densities.

ALPL regulates pro-angiogenic capacity of mesenchymal stem cells through ATP-P2X7 axis controlled exosomes secretion.

Background: Early-onset bone dysplasia is a common manifestation of hypophosphatasia (HPP), an autosomal inherited disease caused by ALPL mutation. ALPL ablation induces prototypical premature bone ageing characteristics, resulting in impaired osteogenic differentiation capacity of human bone marrow mesenchymal stem cells (hBMMSCs). As angiogenesis is tightly coupled with osteogenesis, it also plays a necessary role in sustaining bone homeostasis.

Ultrafast Interlayer Charge Transfer Outcompeting Intralayer Valley Relaxation in Few-Layer 2D Heterostructures.

While 2D transition metal dichalcogenides (TMDs) feature interesting layer-tunable multivalley band structures, their preeminent role in determining the photoexcitation charge transfer dynamics in 2D heterostructures (HSs) is yet to be unraveled, as previous charge transfer studies on TMD HSs have been mostly focused on monolayers with a direct bandgap at the K valley. By ultrafast transient absorption spectroscopy and deliberately designed few-layer WSe/WS HSs, we have observed an ultrafast interlayer electron transfer from photoexcited few-layer WSe to WS, prior to intralayer relaxation to lower lying dark valleys. More interestingly, we have identified an unconventional ∼0.

Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition.

Background: Delayed healing of diabetic cutaneous wounds is one of the most common complications of type 2 diabetes mellitus (T2DM), which can bring great distress to patients. In diabetic patients, macrophages accumulate around skin wounds and produce NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasomes, which in turn undergo pyroptosis and produce inflammatory factors such as interleukin-1β that affect wound healing. Although our previous study revealed that apoptotic extracellular vesicles (ApoEVs) produced from mesenchymal stem cells (MSCs) improve cutaneous wound healing in normal C57BL/6 mice, whether ApoEVs can also improve diabetic wound healing remains unclear.

Phase-pure 2D tin halide perovskite thin flakes for stable lasing.

Ruddlesden-Popper tin halide perovskites are a class of two-dimensional (2D) semiconductors with exceptional optoelectronic properties, high carrier mobility, and low toxicity. However, the synthesis of phase-pure 2D tin perovskites is still challenging, and the fundamental understanding of their optoelectronic properties is deficient compared to their lead counterparts. Here, we report the synthesis of a series of 2D tin perovskite bulk crystals with high phase purity via a mixed-solvent strategy.

Traumatic temporomandibular joint bony ankylosis in growing rats.

Background: The pathogenesis of traumatic temporomandibular joint (TMJ) bony ankylosis remains unknown. This study aimed to explore the pathogenesis of traumatic TMJ bony ankylosis in a rat model.

Methods: Twenty-four 3-week-old male Sprague-Dawley rats were used in this study.

A multifunctional drug consisting of tetracycline conjugated with odanacatib for efficient periodontitis therapy.

The treatment of periodontitis can be very challenging due to its complex etiologies. A new pharmacologic strategy entitled "host-modulation therapy," has been introduced to improve periodontal treatment outcomes. Supposedly, a multifunctional drug with the potential for bacterial infection prevention, host-response modulation and bone healing promotion would be a promising option for periodontitis therapy, but related studies remain substantially lacking.

Platelet count and clinical outcomes among ischemic stroke patients with endovascular thrombectomy in DIRECT-MT.

Objectives: The prognostic role of baseline platelet count (PLT) in acute ischemic stroke patients with large vessel occlusion undergoing endovascular thrombectomy is unclear. Whether PLT modifies alteplase treatment effect on clinical outcome in those patients is also uncertain.

Methods: We derived data from a multicenter randomized clinical trial (DIRECT-MT) comparing intravenous alteplase before endovascular treatment vs.

Immediate, non-submerged, three-dimensionally printed, one-piece mandibular molar porous root-analogue titanium implants: A 2-year prospective study involving 18 patients.

This study prospectively evaluated non-submerged, three-dimensionally printed, one-piece molar porous root-analogue titanium implants. A total of 18 non-restorable multiple-rooted teeth in 18 patients, aged 22-64 years, were included in this study. A series of computed tomography images of the mandible were selected and rendered into a digital model.

Spatiotemporally Coupled Electron-Hole Dynamics in Two Dimensional Heterostructures.

Coulomb interactions play a crucial role in low-dimensional semiconductor materials, e.g., 2D layered semiconductors, dictating their electronic and optical properties.

Selectively Tracking Nanoparticles in Aquatic Plant Using Core-Shell Nanoparticle-Enhanced Raman Spectroscopy Imaging.

Nanoparticles contribute to enormous environmental processes, but, due to analytical challenges, the understanding of nanoparticle fate remains elusive in complex environmental matrices. To address the challenge, a core-shell nanoparticle-enhanced Raman spectroscopy (CSNERS) imaging method was developed to selectively track prevalent SiO nanoparticles in an aquatic plant, . By encapsulating gold nanoparticles and Raman reporters inside, the resonance Raman signature was enhanced, thus enabling the sensitive and selective detection of SiO nanoparticles at an environmentally relevant concentration.

Controlling Photocarrier Lifetime in Graphene for Enhanced Photocurrent Generation via Cascade Hot Electron Transfer.

Because of its broad absorption and high carrier mobility, graphene has been regarded as a promising photoactive material for optoelectronics. However, its ultrashort photoexcited carrier lifetime greatly restricts the device performance. Herein, we show that by constructing a graphene/WS/MoS vertical heterostructure with a cascade electron-transfer pathway, the hot electrons in graphene under low-energy photoexcitation can efficiently transfer through WS to MoS in 180 fs, thus effectively photogating the graphene layer.

Scalable synthesis of multicomponent multifunctional inorganic core@mesoporous silica shell nanocomposites.

Integrating multiple materials with different functionalities in a single nanostructure enables advances in many scientific and technological applications. However, such highly sophisticated nanomaterials usually require complex synthesis processes that complicate their preparation in a sustainable and industrially feasible manner. Herein, we designed a simple general method to grow a mesoporous silica shell onto any combination of hydrophilic nanoparticle cores.

Deciphering asymmetric charge transfer at transition metal dichalcogenide-graphene interface by helicity-resolved ultrafast spectroscopy.

Transition metal dichalcogenide (TMD)/graphene (Gr) heterostructures constitute a key component for two-dimensional devices. The operation of TMD/Gr devices relies on interfacial charge/energy transfer processes, which remains unclear and challenging to unravel. Fortunately, the coupled spin and valley index in TMDs adds a new degree of freedom to the charges and, thus, another dimension to spectroscopy.

Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway.

Objectives: To clarify the possible role and mechanism of Cathepsin K (CTSK) in alveolar bone regeneration mediated by jaw bone marrow mesenchymal stem cells (JBMMSC).

Materials And Methods: Tooth extraction models of Ctsk knockout mice (Ctsk ) and their wildtype (WT) littermates were used to investigate the effect of CTSK on alveolar bone regeneration. The influences of deletion or inhibition of CTSK by odanacatib (ODN) on proliferation and osteogenic differentiation of JBMMSC were assessed by CCK-8, Western blot and alizarin red staining.

Ultrafast Electron Transfer with Long-Lived Charge Separation and Spin Polarization in WSe/C Heterojunction.

The strong excitonic effect in monolayer transition-metal dichalcogenides (TMDs) endows them with intriguing optoelectronic properties but also short-lived population and valley polarization. Exciton dissociation by interfacial charge transfer has been shown as an effective approach to prolonging excited-state lifetimes. Herein, by ultrafast spectroscopy and building-block molecule C, we investigated exciton and valley polarization dynamics in the prototypical WSe/C inorganic-organic hybrid.

TMT-labelled quantitative proteomic analysis to predict the target promoting human odontogenic inflammatory granulation tissue transform into reparative granulation tissue.

Objectives: Odontogenic inflammatory diseases are main causes for alveolar bone breakdown and teeth loss, leaving great difficulties in denture restoration. Local inflammatory granulation tissue (IGT) is considered as pathological tissue and required to be removed. However, there are many evidences supporting that under appropriate intervention, IGT in alveolar bone maybe transformed into reparative granulation tissue (RGT), followed by ossification.