Publications by authors named "Zhou Chuan"

Electroreduction of CO to CO by solid oxide electrolysis cells (SOEC) is an effective means to realize carbon neutralization. However, the sluggish kinetics at SOEC fuel electrode impedes its further practical application. Herein, the doping strategy of cesium ion (Cs) is employed to develop a series of perovskite-type fuel electrode materials, i.

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Objective: Healthcare delivery and research are moving increasingly towards digital engagement, which could inequitably exclude some populations due to differential technology access and uptake. We sought to evaluate study-related digital access, preferences, and use among parents of patients with Medicaid insurance enrolled in research in a pediatric emergency department (ED).

Methods: We conducted a secondary analysis within a randomized trial at an academic pediatric ED.

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Proton exchange membrane water electrolyzers powered by sustainable energy represent a cutting-edge technology for renewable hydrogen generation, while slow anodic oxygen evolution reaction (OER) kinetics still remains a formidable obstacle that necessitates basic comprehension for facilitating electrocatalysts' design. Here, we report a low-iridium complex oxide LaSrIrO with a unique hexagonal structure consisting of isolated Ir(V)O octahedra and true peroxide O groups as a highly active and stable OER electrocatalyst under acidic conditions. Remarkably, LaSrIrO, containing 59 wt % less iridium relative to the benchmark IrO, shows about an order of magnitude higher mass activity, 6-folds higher intrinsic activity than the latter, and also surpasses the state-of-the-art Ir-based oxides ever reported.

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Background: A significant portion of youth sustain a concussion every year, with around 30% experiencing persistent post-concussion symptoms (PPCS). Research has shown exercising just below the exertion level that provokes symptoms can lead to more rapid recovery. However, youth often struggle to adhere to exercise recommendations following concussion.

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Atom-centered neural network (ANN) potentials have shown high accuracy and computational efficiency in modeling atomic systems. A crucial step in developing reliable ANN potentials is the proper selection of atom-centered symmetry functions (ACSFs), also known as atomic features, to describe atomic environments. Inappropriate selection of ACSFs can lead to poor-quality ANN potentials.

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Acute kidney injury (AKI) has been noticed after both COVID-19 vaccination and infection, affecting risk-benefit evaluations and vaccine hesitancy. We conducted a large-scale N3C cohort study to compare AKI incidence following COVID-19 vaccination and infection. Participants from December 2020 to August 2023 were divided into two groups based on their initially observed COVID-19 antigen exposure: COVID-19 vaccination group (n = 2,953,219) and COVID-19 infection group (n = 3,616,802).

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Article Synopsis
  • - BPA is a harmful endocrine disruptor that negatively affects crop growth and poses risks to sustainable agriculture and human health.
  • - A new membrane called TpBD-COF, composed of a water-stabilized imine covalent organic framework, effectively removes BPA by utilizing smaller pores to enhance selective absorption.
  • - This innovative membrane achieves a BPA removal efficiency that is 5.79 times greater than traditional membranes and could greatly benefit agricultural irrigation by cleaning wastewater and supporting crop health.
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  • The study examines how people learn the emotional meaning of words in changing environments, emphasizing the importance of external feedback.
  • It integrates reinforcement learning with emotional word acquisition, using a probabilistic reversal learning task to understand how expectations influence learning speed and processing of emotional words.
  • Results show that individuals learn negative emotional words more quickly and intensely as expected rewards increase, highlighting a neural bias towards negative information in volatile settings.
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Introduction: SOS1 is a crucial guanine nucleotide exchange factor for KRAS. It facilitates the transition of KRAS from inactive GDP-bound state to active GTP-bound state. The activation of KRAS triggers downstream signaling pathways, promoting tumor initiation and progression.

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Few biological or clinical predictors guide medication selection and/or dosing for attention-deficit/hyperactivity disorder (ADHD). Accumulating data suggest that genetic factors may contribute to clinically relevant pharmacodynamic (e.g.

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Article Synopsis
  • Up to 1.9 million youth in the US experience concussions yearly, with 30% suffering long-term symptoms that affect their daily lives, yet effective treatments are limited.
  • A collaborative care model that includes cognitive behavioral therapy, parenting skills training, and care management has previously shown promise in improving conditions for these youth.
  • This study will evaluate the effectiveness of each care component through a factorial design, involving 368 participants from Seattle and Dallas, to optimize treatment strategies for youth with persistent post-concussive symptoms.
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School closures and restrictions related to the COVID-19 pandemic changed opportunities for youth physical activity (PA). We sought to identify school and other contextual conditions associated with youth PA during the COVID-19 pandemic. A nationally representative, United States sample consisted of 500 parents of children ages 6-10 years old and 500 parent-child dyads with children and adolescents ages 11-17 years old who completed a web-based questionnaire.

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Article Synopsis
  • Inflammatory bowel disease (IBD) encompasses conditions like ulcerative colitis and Crohn's disease, with causes linked to genetics, the environment, and interactions between gut microbiota and the immune system.
  • Intestinal macrophages are crucial in IBD, influencing disease progression, inflammation, and gut health, while dysregulation can lead to increased intestinal inflammation.
  • The review also evaluates various treatments like 5-ASA, antibiotics, and probiotics, suggesting that strategies such as fecal microbiota transplantation hold promise for improving IBD management by targeting the gut microbiome and macrophage function.
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Presently, ethylene oxide (EtO) is posing a significant threat to both human health and the environment due to occasional or deliberate emissions. However, few works so far have focused on this issue. It is urgent to explore novel and effective technology to protect against the threat of EtO.

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Article Synopsis
  • Fecal microbiota transplantation (FMT) shows promise for treating inflammatory bowel disease (IBD), but its effectiveness can vary significantly among individuals.
  • Research indicates that the stimulator of interferon genes (STING), a protein involved in immune response, plays a critical role in how well FMT works by regulating immune cell differentiation and improving gut health.
  • The study suggests that STING could serve as a biomarker to identify which patients are best suited for FMT, potentially leading to more effective treatment strategies.
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Overactivation of the stress response can influence cancer outcomes through immune-related pathways. Adolescents and young adults (AYAs) undergoing hematopoietic cell transplantation (HCT) are at risk for poor outcomes, yet there are limited behavioral interventions and no psychosocial biomarker data for this population. The Conserved Transcriptional Response to Adversity (CTRA) is an inflammation-related pattern observed in conditions of heightened stress and is associated with HCT outcomes.

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Objective: To investigate the protective effect of lanthanum chloride on kidney injury in chronic kidney disease and its mechanism.

Methods: 1. Patients with CKD stage 2-5 were selected to analyze the effect of lanthanum-containing preparations on CKD.

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Objective: Parent behavior management training (BMT) is an evidence-based yet underutilized tool to treat children with ADHD and address related health disparities. This pilot study investigated the acceptability and feasibility of a novel, health behavior-, and technology-adapted BMT (LEAP) vs. standard BMT.

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Angiogenesis plays a pivotal role in the progression and metastasis of solid cancers, including prostate cancer (PCa). While small extracellular vesicles derived from PCa cell lines induce a proangiogenic phenotype in vascular endothelial cells, the contribution of plasma exosomes from patients with PCa to this process remains unclear. Here, we successfully extracted and characterized plasma exosomes.

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Female sexual receptivity is essential for reproduction of a species. Neuropeptides play the main role in regulating female receptivity. However, whether neuropeptides regulate female sexual receptivity during the neurodevelopment is unknown.

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Article Synopsis
  • This study investigates the use of plasma exosomal microRNAs, ultrasound imaging features, and total PSA levels to improve early prostate cancer detection.
  • Analysis of the GSE112264 dataset identified relevant microRNAs, and a diagnostic model was developed using various evaluation techniques to assess its effectiveness.
  • The final model, which integrated specific microRNAs (hsa-miR-320c and hsa-miR-944) along with radiomics and tPSA, achieved high accuracy in predicting prostate cancer, outperforming single index models.
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Importance: Type 1 diabetes (T1D) requires demanding self-management health behaviors, and adolescents with T1D are at risk for poor psychosocial and medical outcomes. Developing resilience skills may help adolescents with T1D and elevated distress navigate common stressors and achieve positive outcomes.

Objective: To test the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention on levels of hemoglobin A1c (HbA1c), diabetes distress, self-management behaviors, resilience, and quality of life among adolescents.

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Fragrant peanut oils (FPOs) are commonly defined as edible peanut oils having strong natural roasted peanut flavor without peculiar unpleasant odors and produced from peanut kernels through roasting/steaming and pressing operations, etc. The flavor of FPOs plays a crucial role in their acceptability and applications and their flavor profiles are an important factor in determining their overall quality. This paper presents a systematic literature review of recent advances and knowledge on FPOs, especially their flavors, in which it is focused on the evaluation of volatile compounds, the factors influencing the formation of flavor compounds, and formation mechanisms of those typical flavor compounds.

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Background: The effectiveness of laparoscopic nephroureterectomy (LNU) vs open nephroureterectomy (ONU) for upper tract urothelial carcinoma (UTUC) is unclear.

Methods: We conducted a meta-analysis of studies based on propensity score-matched cohorts to compare the surgical and oncological outcomes of LNU and ONU in UTUC patients. A literature search was conducted on PubMed, Embase, and Cochrane Library until July 12, 2023.

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Background: Adolescents and young adults (AYAs) with cancer are at risk of poor psychosocial outcomes. AYAs grew up with the internet and digital technology, and mobile Health (mHealth) psychosocial interventions have the potential to overcome care access barriers.

Objective: This pilot randomized controlled trial (RCT) aimed to establish the feasibility, acceptability, and preliminary efficacy of a fully automated mobile app version of the Promoting Resilience in Stress Management intervention (mPRISM).

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