Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.

Background: The association between mitochondrial dysfunction and multiple metabolic adaptations is increasingly being proven. We previously elucidated that mitochondrial complex I deficiency can promote glycolysis in mut-p53 SW480 cells. However, studies have revealed a phenotype with attenuated glycolysis but enhanced fatty acid oxidation (FAO) in invasive tumors.

Risk and related factors of elbow musculoskeletal diseases: a nationwide cross-sectional survey in China.

Objectives: Although studies have shown that work-related musculoskeletal disorders (WMSDs) are common and continue to be a major source of disability and work time loss, there are few reports about elbow WMSDs. The aim of this study was to explore the prevalence and associated factors of elbow WMSDs.

Methods: The valid questionnaires of 57501 workers from 15 different industries nationwide were collected and the c2 test and logistic regression analysis were applied to reveal the prevalence and risk factors of elbow WMSDs.

Effects of Simulated Acid Rain on Photosynthesis in and in Terms of Prompt Fluorescence, Delayed Fluorescence, and Modulated Reflection at 820 nm.

The effects of simulated acid rain (SAR) on the photosynthetic performance of subtropical coniferous species have not been thoroughly investigated. In this study, we treated two coniferous species, (PM) and (CL), with four gradients of SAR and then analyzed their photosynthetic activities through measurements of gas exchange, prompt fluorescence (PF), delayed fluorescence (DF), and modulated reflection at 820 nm (MR). Gas exchange analysis indicated that the decrease in the net photosynthetic rate (Pn) in PM and CL was unrelated to stomatal factors.

α-Ketoglutarate Improves Ovarian Reserve Function in Primary Ovarian Insufficiency by Inhibiting NLRP3-Mediated Pyroptosis of Granulosa Cells.

Scope: Premature ovarian insufficiency (POI) is a common female infertility problem, with its pathogenesis remains unknown. The NOD-like receptor family pyrin domain-containing 3 (NLRP3)-mediated pyroptosis has been proposed as a possible mechanism in POI. This study investigates the therapeutic effect of α-ketoglutarate (AKG) on ovarian reserve function in POI rats and further explores the potential molecular mechanisms.

Review on Main Gate Characteristics of P-Type GaN Gate High-Electron-Mobility Transistors.

As wide bandgap semiconductors, gallium nitride (GaN) lateral high-electron-mobility transistors (HEMTs) possess high breakdown voltage, low resistance and high frequency performance. PGaN gate HEMTs are promising candidates for high-voltage, high-power applications due to the normally off operation and robust gate reliability. However, the threshold and gate-breakdown voltages are relatively low compared with Si-based and SiC-based power MOSFETs.

A surface modification strategy to prepare hierarchical Beta molecular sieves for glucose dehydration.

In order to balance the contradiction between mesopore introduction and loss of microporosity, a surface modification strategy is proposed by selectively adsorbing organic alkaline molecules on Beta molecular sieves before NaOH etching. Organic alkaline molecules adsorb on framework aluminum sites and the protective function of organic bases is affected by the adsorption configuration and physical barrier effect of organic bases. Organic alkaline molecules serve as a protective agent to increase the bond length of Al-O bonds.

Machine-learning-accelerated screening of single metal atoms anchored on MnPS monolayers as promising bifunctional oxygen electrocatalysts.

Searching for bifunctional oxygen electrocatalysts with good catalytic performance to promote the oxygen evolution/reduction reactions (OER/ORR) is of great significance to the development of sustainable and renewable clean energy. Herein, we performed density functional theory (DFT) and machine-learning (DFT-ML) hybrid computations to investigate the potential of a series of single transition metal atoms anchored on the experimentally available MnPS monolayer (TM/MnPS) as the bifunctional electrocatalysts for the ORR/OER. The results revealed that the interactions of these metal atoms with MnPS are rather strong, thus guaranteeing their high stability for practical applications.

Interface engineering of transition metal-nitrogen-carbon by graphdiyne for boosting the oxygen reduction/evolution reactions: A computational study.

Exploring high-efficiency electrocatalysts to boost the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is pivotal to the large-scale applications for clean and renewable energy technologies, such as fuel cells, water splitting, and metal-air batteries. Herein, by means of density functional theory (DFT) computations, we proposed a strategy to modulate the catalytic activity of transition metal-nitrogen-carbon catalysts through their interface engineering with graphdiyne (TMNC/GDY). Our results revealed that these hybrid structures exhibit good stability and excellent electrical conductivity.

Epidemiological study of work-related musculoskeletal disorders and related risk factors among automobile maintenance workers.

Background: The automotive industry is labor-intensive, and workers are involved in highly repetitive tasks, long hours, and medium to low workloads, resulting in work-related musculoskeletal disorders (WMSDs), which have become a major health concern for workers in this industry. China is a major automotive country with tens of thousands of auto repair workers, but their conditions of WMSDs have been poorly reported.

Objective: This work aimed to analyze the current prevalence of WMSDs and their associated risk factors among automobile maintenance workers.

The association between adverse ergonomic factors and work-related musculoskeletal symptoms among medical staff in China: a cross-sectional study.

We investigated the prevalence of work-related musculoskeletal symptoms (WMSs) among medical staff and evaluated the associations of different levels of adverse ergonomic factors with WMSs. A total of 6099 Chinese medical staff were asked to complete a self-reported questionnaire to assess the prevalence and risk factors of WMSs from June 2018 to December 2020. A prevalence rate of 57.

Incidence and Risk Factors of the Upper-Limb Musculoskeletal Disorders Among Occupational Groups in Key Industries - China, 2018-2021.

What Is Already Known About This Topic?: The burden of illness and economic losses due to upper-limb work-related musculoskeletal disorders (UL-WMSDs) is high; thus, they have become a major global public health problem. At present, the epidemiological characteristics of UL-WMSDs in China's occupational population are still unknown.

What Is Added By This Report?: The incidence of UL-WMSDs among key occupational groups in China is 22.

The prevalence and risk factors of work related musculoskeletal disorders among electronics manufacturing workers: a cross-sectional analytical study in China.

Objectives: To describe the prevalence of self-reported musculoskeletal disorders among workers in the electronics manufacturing industry and to investigate the relations between work-related musculoskeletal disorders (WMSDs) and work-related variables.

Methods: An interview-based questionnaire survey was carried out in thirty electronics manufacturing factories in China in 2018. The prevalence of WMSDs was estimated using the modified Nordic Musculoskeletal Questionnaire (NMQ).

Epidemiological study of multi-site WMSDs in the footwear industry in China.

. This study aimed to identify the prevalence of multi-site work-related musculoskeletal disorders (WMSDs) in Chinese footwear industry workers from 2018 to 2020 and explore the possible influencing factors of WMSDs. .

Prevalence status and associated factors of wrist postural injury in the Chinese occupational population.

Objective: This study investigated the prevalence of wrist injuries in 15 industries and different types of work in China. Study on the associated factors of wrist injuries provides a scientific basis for prevention and treatment of wrist diseases in occupational workers.

Methods: A cross-sectional study of musculoskeletal symptoms of related practitioners in 15 industries, including automobile manufacturing, was conducted to retrieve worker demographic information, working wrist posture, and pain conditions.

Shoulder work-related musculoskeletal disorders and related factors of workers in 15 industries of China: a cross-sectional study.

Background: Changes in modern industrial production practices can easily lead to shoulder work-related musculoskeletal disorders (WMSD). The current reports on shoulder WMSD are limited to some industries are less well studied, and the sample size is usually small. This study aimed to describe the prevalence and severity of shoulder WMSD in a large sample of Chinese workers from 15 industries, analyze the possible correlations with sociodemographic and work-related variables, and compare the differences between industries.

Multi-Site Musculoskeletal Symptoms in the Electronics Manufacturing Industry in China: A Cross-Sectional Study.

Background: With the development of the electronics manufacturing industry, the demand for human resources has increased, which has also led to the frequent occurrence of multi-site work-related musculoskeletal disorders.

Method: The participants ( = 7307) were recruited from 30 enterprises in China in 2018. The prevalence of musculoskeletal disorders was estimated using a modified Chinese version of the Musculoskeletal Disorders Questionnaire.

N-Doped CrS Monolayer as a Highly-Efficient Catalyst for Oxygen Reduction Reaction: A Computational Study.

Searching for low-cost and highly-efficient oxygen reduction reaction (ORR) catalysts is crucial to the large-scale application of fuel cells. Herein, by means of density functional theory (DFT) computations, we proposed a new class of ORR catalysts by doping the CrS monolayer with non-metal atoms (X@CrS, X = B, C, N, O, Si, P, Cl, As, Se, and Br). Our results revealed that most of the X@CrS candidates exhibit negative formation energy and large binding energy, thus ensuring their high stability and offering great promise for experimental synthesis.

Prevalence and risk factors analysis for low back pain among occupational groups in key industries of China.

Background: With the acceleration of industrialization and population aging, low back pain (LBP) has become the leading cause of life loss years caused by disability. Thus, it places a huge economic burden on society and is a global public health problem that needs urgent solution. This study aimed to conduct an epidemiological investigation and research on a large sample of workers in key industries in different regions of China, determine the incidence and distribution characteristics of LBP, explore the epidemic law, and provide a reference basis for alleviating global public health problems caused by LBP.

Decoupling layer metal-organic frameworks ligand regulation to achieve ultra-thin carbon nanosheets for oxygen reduction electrocatalysis.

2D imidazole MOFs are considered to be ideal carbon precursors for oxygen reduction reactions owing to their adjustable ligand components and durable coordination mode. Due to the massive electron delocalization in the lamella, the conjugative effect among 2D MOF layers immensely restricts the exposure of catalytic sites after carbonization, which makes the decoupling layer extremely important on the premise of ensuring activity. Herein, atomic thickness ultra-thin zinc-imidazole MOF precursors were prepared through a bottom-up ligand regulated strategy to achieve the aim of lamellar decoupling.

Computational screening of single-atom catalysts supported by VS monolayers for electrocatalytic oxygen reduction/evolution reactions.

The development of highly efficient bifunctional electrocatalysts to boost oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is highly desirable for energy conversion and storage devices. Herein, by means of comprehensive first-principles computations, we systematically explored the catalytic activities of a series of single transition metal atoms anchored on two-dimensional VS monolayers (TM@VS) for ORR/OER. Our results revealed that Ni@VS exhibits low overpotentials for both ORR (0.

Prevalence and risk factors for MSDs in vegetable greenhouse farmers: a cross-sectional survey from Shandong rural area, China.

Purpose: The aim of the research is a cross sectional survey on the prevalence of symptoms related to MSDs in vegetable greenhouse farmers from Shandong rural area and on the risk factors that may influence it.

Methods: This cross-sectional survey was selected 249 farmers working in vegetable greenhouse from different districts of Shandong Province, China. The Questionnaire and the Rapid Upper Limb Assessment (RULA) technique were used to identify ergonomic risks.

Epidemiological Data of Work-Related Musculoskeletal Disorders - China, 2018-2020.

What Is Already Known About This Topic?: In recent decades, work-related musculoskeletal disorders (WMSDs) have become increasingly prominent and have become an important issue that is of universal concern and an urgent need to be solved in all countries of the world.

What Is Added By This Report?: The top three industries or occupational groups with the highest standardized prevalence rate of WMSDs were flight attendants, medical staff, and vegetable greenhouses in that order. Women workers were 1.

Controlled 2H/1T phase transition in MoS monolayers by a strong interface with MC MXenes: a computational study.

Due to the high conductivity and abundant active sites, the metallic 1T phase of a two-dimensional molybdenum sulfide monolayer (1T-MoS) has witnessed a broad range of potential applications in catalysis, and spintronic and phase-switching devices, which, however, are greatly hampered by its poor stability. Thus, the development of particular strategies to realize the phase transition from the stable 2H phase to the metastable 1T phase for MoS nanosheets is highly desirable. Herein, by means of density functional theory (DFT) computations, we systematically explored the potential of the interfacial interaction of 2H- and 1T-MoS monolayers with a series of MC MXenes (M = Ti, V, Cr, Zr, Nb, Mo, Hf, Ta, and W) for achieving the 2H/1T phase transformation.