ACS Appl Mater Interfaces
October 2024
Zwitterionic peptides, as a type of peptide composed of charged residues, are electrically neutral, which combine the advantages of zwitterionic materials and biological peptides, exhibiting hydrophilicity and programmable properties. As attractive candidates for resisting nonspecific adsorption of biomacromolecules and microorganisms, zwitterionic peptides have been applied in materials science, biomedicine, and biochemistry over the past decade. In this review, the development of zwitterionic peptides has been systematically outlined and analyzed, including their mechanisms, structure-function relationships, and design strategies.
View Article and Find Full Text PDFCurcumin demonstrated therapeutic potential for cancer. However, its medical application is limited due to low solubility, poor stability and low absorption rate. Here, we used the mussel-inspired functional protein (MPKE) to fabricate the curcumin-carrying nanoparticle (Cur-MPKE) for encapsulating and delivering curcumin.
View Article and Find Full Text PDFCryopreservation can prolong the viability of cells and help meet the demand for biosamples of high medical value. Cryoprotectants (CPAs) can mitigate unavoidable cell cryoinjury caused by the formation and growth of ice crystals during freeze-thaw cycles. Therefore, the development of efficient and biocompatible CPAs has attracted extensive attention.
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