Clobetasol Attenuates White Matter Injury by Promoting Oligodendrocyte Precursor Cell Differentiation.

Introduction: White matter injury (WMI) is the most common brain injury in preterm infants and can result in life-long neurological deficits. The main cause of WMI is damage to the oligodendrocyte precursor cells (OPC) in the brain that results in delayed myelin sheath formation, or the destruction of existing myelin sheaths. OPC undergo highly regulated and strictly timed developmental changes that result in their transformation to mature oligodendrocytes capable of myelin production.

Knockdown of STIL suppresses the progression of gastric cancer by down-regulating the IGF-1/PI3K/AKT pathway.

SCL/TAL1 interrupting locus (STIL) regulates the mitotic centrosome to promote the centriolar replication and cell cycling, and is associated with malignancies. However, the role and mechanism of STIL in gastric cancer (GC) remain elusive. STIL expression in GC tissue microarray was detected by immunohistochemistry (IHC).

Down-Regulation of miR-218-5p Promotes Apoptosis of Human Umbilical Vein Endothelial Cells Through Regulating High-Mobility Group Box-1 in Henoch-Schonlein Purpura.

Background: Apoptosis of human umbilical vein endothelial cells (HUVECs) plays an important role in the progression of Henoch-Schonlein purpura (HSP). In the present study, we explored the function of miR-218-5p in HUVEC apoptosis and HSP development.

Materials And Methods: HSP rat model was established and peripheral blood mononuclear cells (PBMC) were isolated.

Circular stapler-assisted extraperitoneal colostomy.

Aims: To report and evaluate the clinical value of circular stapler-assisted extraperitoneal colostomy.

Methods: We performed circular stapler-assisted extraperitoneal colostomy following Miles' operation in 22 patients over a 2-year period from March 2007 to March 2009. The efficiency and safety of the operation were evaluated.