MM-NeRF: Multimodal-Guided 3D Multi-Style Transfer of Neural Radiance Field.

3D style transfer aims to generate stylized views of 3D scenes with specified styles, which requires high-quality generating and keeping multi-view consistency. Existing methods still suffer the challenges of high-quality stylization with texture details and stylization with multimodal guidance. In this paper, we reveal that the common training method of stylization with NeRF, which generates stylized multi-view supervision by 2D style transfer models, causes the same object in supervision to show various states (color tone, details, etc.

sp. nov., a thermophilic bacterium isolated from an anaerobic reactor degrading propionate.

An anaerobic, Gram-stain-positive, spore-forming bacterium, designated strain PYR-10, was isolated from a mesophilic methanogenic consortium. Cells were 0.7-1.

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos.

Conventional embryonic stem cell (ESC)-based gene targeting, zinc-finger nuclease (ZFN) and transcription activator-like effector nuclease (TALEN) technologies are powerful strategies for the generation of genetically modified animals. Recently, the CRISPR/Cas system has emerged as an efficient and convenient alternative to these approaches. We have used the CRISPR/Cas system to generate rat strains that carry mutations in multiple genes through direct injection of RNAs into one-cell embryos, demonstrating the high efficiency of Cas9-mediated gene editing in rats for simultaneous generation of compound gene mutant models.

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases.

Transcription activator-like effector nucleases (TALENs) are a powerful new approach for targeted gene disruption in various animal models, but little is known about their activities in Mus musculus, the widely used mammalian model organism. Here, we report that direct injection of in vitro transcribed messenger RNA of TALEN pairs into mouse zygotes induced somatic mutations, which were stably passed to the next generation through germ-line transmission. With one TALEN pair constructed for each of 10 target genes, mutant F0 mice for each gene were obtained with the mutation rate ranged from 13 to 67% and an average of ∼40% of total healthy newborns with no significant differences between C57BL/6 and FVB/N genetic background.

Lgr4-mediated Wnt/β-catenin signaling in peritubular myoid cells is essential for spermatogenesis.

Peritubular myoid cells (PMCs) are myofibroblast-like cells that surround the seminiferous tubules and play essential roles in male fertility. How these cells modulate spermatogenesis and the signaling pathways that are involved are largely unknown. Here we report that Lgr4 is selectively expressed in mouse PMCs in the testes, and loss of Lgr4 leads to germ cells arresting at meiosis I and then undergoing apoptosis.

PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop.

Cell growth and proliferation are tightly controlled via the regulation of the p53-MDM2 feedback loop in response to various cellular stresses. In this study, we identified a nucleolar protein called PAK1IP1 as another regulator of this loop. PAK1IP1 was induced when cells were treated with chemicals that disturb ribosome biogenesis.