Association between periodontal disease and atherosclerosis: a bibliometric analysis.

Background: In recent years, the relationship between periodontal disease (PD) and atherosclerosis (AS) has garnered significant scholarly attention. Chronic inflammation induced by PD may promote the onset and progression of AS through multiple mechanisms. Given the increasing global incidence of both PD and AS, which adversely affects patients' quality of life and longevity, further investigation into the interplay between PD and AS is of substantial clinical importance.

Genetically predicted obstructive sleep apnea is causally associated with an increased risk for periodontitis.

Background: Although obstructive sleep apnea (OSA) and periodontitis are associated, whether this association is causative is uncertain.

Methods: We conducted a bidirectional Mendelian randomization (MR) analysis using data from publically accessible genome-wide association studies. The single-nucleotide polymorphisms (SNPs) for OSA were derived from 16,761 cases and 201,194 controls.

The effect of APN, hs-CRP and APN/hs-CRP in periodontitis with DAA.

Background: Common chronic infections induced low-grade inflammation has been correlated with atherosclerosis as supported by strong evidence. The balance between pro-and anti-inflammatory factors was exploited to elucidate the effects of chronic periodontitis on diabetes-associated atherosclerosis.

Methods: Study subjects encompassed 30 SPF male rats randomly divided into four groups: A group (NC), B group (T2DM), C group (CP), D group (DM + CP).

The underlying molecular mechanisms and biomarkers of plaque vulnerability based on bioinformatics analysis.

Aim: The study aimed to identify the underlying differentially expressed genes (DEGs) and mechanism of unstable atherosclerotic plaque using bioinformatics methods.

Methods: GSE120521, which includes four unstable samples and four stable atherosclerotic samples, was downloaded from the GEO database. DEGs were identified using LIMMA.