Publications by authors named "Zhongqi Feng"
Article Synopsis
- The original publication discusses key concepts and findings related to the topic at hand.
- It highlights significant research methods used in the study and their implications.
- The conclusions drawn provide insights into future directions for study and practical applications.
Article Synopsis
- O-GlcNAc modification and ubiquitination are important processes that help control how cancer grows and spreads.
- SKP2 is a protein that helps manage the cell cycle, and researchers discovered it interacts with a molecule called OGT in liver cancer cells.
- When SKP2 is modified by O-GlcNAc, it stays stable longer and helps push the cancer cells to grow, suggesting that stopping this modification could help treat the cancer.
The self-absorption effect in an optically thick plasma seriously affects the spectral line intensity and the measurement accuracy of laser-induced breakdown spectroscopy (LIBS). In this work, a self-absorption correction method based on intensity self-calibration of doublet lines belonging to the same multiplet is proposed. The K/Δλ parameter and self-absorption coefficient (SA) of the doublet lines of the analytical element can be calculated based on the measured actual lines intensity ratio and the K parameters ratio.
View Article and Find Full Text PDFO-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N-methyladenosine-dependent manner.
Signal Transduct Target Ther
February 2023
Hepatitis B virus (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC), but its pathogenic mechanism remains to be explored. The RNA N-methyladenosine (mA) reader, YTH (YT521-B homology) domain 2 (YTHDF2), plays a critical role in the HCC progression. However, the function and regulatory mechanisms of YTHDF2 in HBV-related HCC remain largely elusive.
View Article and Find Full Text PDFThe hepatitis B virus (HBV) capsid assembly modulators (CAMs) have been developed as effective anti-HBV agents in the treatment of chronic HBV infection by targeting the HBV core protein and inducing the formation of aberrant or morphologically normal capsid. However, some CAMs have been observed adverse events such as ALT flares and rash. Therefore, finding new CAMs is of great importance.
View Article and Find Full Text PDFArticle Synopsis
- A new portable laser system was tested for analyzing essential electrolytes (K, Na, Ca) in human blood serum using laser-induced breakdown spectroscopy (LIBS).
- The study employed partial least squares regression (PLSR) to predict the concentrations of these electrolytes from the LIBS data, achieving high prediction accuracy.
- Results showed that the portable LIBS system, capable of real-time analysis, could significantly benefit clinical practices for detecting and diagnosing diseases.