A leak K channel TWK-40 sustains the rhythmic motor program.

Leak potassium (K) currents, conducted by two-pore domain K (K) channels, are critical for the stabilization of the membrane potential. The effect of K channels on motor rhythm remains enigmatic. We show here that the K TWK-40 contributes to the rhythmic defecation motor program (DMP) in .

Escape steering by cholecystokinin peptidergic signaling.

Escape is an evolutionarily conserved and essential avoidance response. Considered to be innate, most studies on escape responses focused on hard-wired circuits. We report here that a neuropeptide NLP-18 and its cholecystokinin receptor CKR-1 enable the escape circuit to execute a full omega (Ω) turn.