Spectral sidebands of dissipative soliton in a positive fourth-order-dispersion fiber laser.

Recently, the dissipative soliton (DS) generation in the positive fourth-order-dispersion (FOD) fiber laser has been theoretically predicted, namely dissipative pure-quartic soliton (DPQS), featuring a higher energy-scaling ability compared to conventional DS dominated by positive group velocity dispersion. Here, we discover that the formation of spectral sidebands is always accompanying by the stabilized DPQS in the fiber laser, which is different from the conventional DS. Due to the combination of positive FOD and self-phase modulation, low- and high-frequency components are distributed at the leading and trailing edges of the pulse, forming the pedestals that propagate with it.

Eu/Tb-MOF as fluorescence sensors for the detection homocysteine in human serum performance and mechanistic investigation.

Abnormal homocysteine (Hcy) levels in human serum have been associated with serious or vital diseases, making the reliable and easy detection of Hcy important to clinical analysis and biological study. In this work, five phosphorescent Ir(C^N)(N^N) complexes (Ir) having aldehyde group were synthesized as probes (C^N and N^N denoted ligands). A discussion was conducted on their molecular structure, electronic structure, photophysical parameters, and Hcy sensing ability, revealing the correlations between their molecular structures and performances.

The prognostic value of Forkhead box P3 regulatory T cells in biliary tract cancer: A systematic review and meta-analysis.

Background: This study aimed to explore the value of tumor-infiltrating Forkhead box P3(FoxP3+) regulatory T cells (Tregs) in evaluating the prognosis of biliary tract cancer.

Methods: Four electronic databases were searched using 2 computers: PubMed, Embase, Web of Science, and Cochrane Library. The vocabulary and syntax were adapted according to the database.

Association of depressive symptoms with the progression of carotid intima-media thickness in a community-based cohort in Beijing, China.

Objectives: To determine the relationship between depressive symptoms and progression of carotid intima-media thickness (cIMT) in a Beijing community-based population.

Design: Prospective cohort study between 2014 and 2018.

Setting: Dwellers without cardiovascular disease, hypertension or diabetes from a Beijing community.

Heart Rate Predicts the Risk of New-Onset Peripheral Arterial Disease in a Community-Based Population in China.

Introduction: Elevated heart rate is linked with poor prognosis and has been shown to accelerate the progress of atherosclerosis. However, the association between heart rate and new-onset PAD is unknown.

Methods: A total of 3463 participants without PAD at baseline from a community-based cohort in Beijing were included and followed up for 2.

Lipid profiles and the risk of new-onset hypertension in a Chinese community-based cohort.

Background And Aims: Dyslipidemia and hypertension, key risk factors for cardiovascular disease, may share similar pathophysiological processes. A longitudinal association was reported between dyslipidemia and new-onset hypertension, but few data were published in Asian. We aimed to investigate the association of lipid profiles with new-onset hypertension in a Chinese community-based non-hypertensive cohort without lipid-lowering treatment (n = 1802).

Brachial-ankle pulse wave velocity is independently associated with urine albumin-to-creatinine ratio in a Chinese community-based cohort.

Purpose: Arterial stiffness is important in the development of albuminuria. The brachial-ankle pulse wave velocity (baPWV) acts as an indicator of arterial stiffness and may be associated with cardiovascular disease morbidity and mortality. The urine albumin-to-creatinine ratio (UACR) is a metric used to diagnose albuminuria and has also been shown to be associated with cardiovascular disease.

Kidney function predicts the risk of asymptomatic peripheral arterial disease in a Chinese community-based population.

Purpose: Lower-extremity peripheral arterial disease (PAD) can predict the risk of subsequent cardiovascular disease (CVD) and all-cause mortality. Chronic kidney disease (CKD) as a precursor of CVD has been proven to be independently associated with PAD. However, few data exist regarding the prediction value of kidney function for incident asymptomatic PAD in community-based populations.

Metabolic Syndrome Is Associated With Rapid Estimated Glomerular Filtration Rate Decline In A Chinese Community-Based Population.

Purpose: This study aimed to determine the relationship between the metabolic syndrome (MetS) and rapid estimated glomerular filtration rate (eGFR) decline in a Chinese community-based population.

Patients And Methods: A total of 3108 participants were recruited between December 2011 and July 2014 from an observational study cohort designed for the study of atherosclerotic diseases in Beijing, China. The outcome was a rapid eGFR decline.

An Extended Kalman Filter and Back Propagation Neural Network Algorithm Positioning Method Based on Anti-lock Brake Sensor and Global Navigation Satellite System Information.

Telematics box (T-Box) chip-level Global Navigation Satellite System (GNSS) receiver modules usually suffer from GNSS information failure or noise in urban environments. In order to resolve this issue, this paper presents a real-time positioning method for Extended Kalman Filter (EKF) and Back Propagation Neural Network (BPNN) algorithms based on Antilock Brake System (ABS) sensor and GNSS information. Experiments were performed using an assembly in the vehicle with a T-Box.

Novel non-trimethoxylphenyl piperlongumine derivatives selectively kill cancer cells.

Piperlongumine (PL) is a natural alkaloid with broad biological activities. Twelve analogues have been designed and synthesized with non-substituted benzyl rings or heterocycles in this work. Most of the compounds showed better anticancer activities than the parent PL without apparent toxicity in normal cells.

Small molecules inhibiting Keap1-Nrf2 protein-protein interactions: a novel approach to activate Nrf2 function.

Oxidative stress is well recognized to contribute to the cause of a wide range of diseases, such as cancer, diabetes, Alzheimer's disease, arteriosclerosis, and inflammation. The Keap1-Nrf2-ARE pathway plays a critical regulatory role and can protect cells from oxidative stress through activating Nrf2 to induce its downstream phase II enzymes. Nrf2 activation through the covalent inactivation of Keap1 may cause unpredictable side effects.

Concentration-Dominated Temperature-Dependence of Upconversion Luminescence in Gd6WO12 Nanophosphor Co-Doped with Er3+ and Yb3+.

Nanosized Gd6WO12 phosphors containing various Er3+ concentrations and fixed Yb3+ concentration were synthesized by a co-precipitation method. The crystal structure and microscopic morphology of the obtained nanophosphors were characterized by means of X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM). Two-photon processes for both the green and red upconversion (UC) emissions were confirmed by analyzing the dependence of UC intensities on 980 nm laser working current.