A formula for instability-related bone loss: estimating glenoid width and redefining bare spot.

Purpose: The aim of the study reveals a new intuitive method for preoperatively assessing defect ratio in glenoid deficiency based on the native glenoid width and the bare spot.

Methods: A linear relationship, i.e.

3D MRI PD-SPACE-COR Predicting Safety Margin for Coracoid Transfer.

Objective: The maximum bone length available for coracoid process transfer varies among individuals, while no preoperative guideline has been developed for predicting the safety margin (SM) in Latarjet shoulder reconstruction. The aim of the study was to evaluate the 3D MRI proton density (PD)-weighted sampling perfection with application-optimized contrasts using different flip-angle evolution (SPACE) sequence in preoperatively predicting SM for coracoid transfer.

Methods: The post-multiplanar reconstructed images were obtained from 24 volunteers (17 males, seven females) to determine the clarity and sensitivity of the PD-SPACE-COR and PD-SPACE-FS-COR protocols.

Effects of advanced glycation end products (AGEs) on the differentiation potential of primary stem cells: a systematic review.

The formation and accumulation of advanced glycation end products (AGEs) have been associated with aging and the development, or worsening, of many degenerative diseases, such as atherosclerosis, chronic kidney disease, and diabetes. AGEs can accumulate in a variety of cells and tissues, and organs in the body, which in turn induces oxidative stress and inflammatory responses and adversely affects human health. In addition, under abnormal pathological conditions, AGEs create conditions that are not conducive to stem cell differentiation.

Resonance and bifurcation of fractional quintic Mathieu-Duffing system.

In this paper, the main subharmonic resonance of the Mathieu-Duffing system with a quintic oscillator under simple harmonic excitation, the route to chaos, and the bifurcation of the system under the influence of different parameters is studied. The amplitude-frequency and phase-frequency response equations of the main resonance of the system are determined by the harmonic balance method. The amplitude-frequency and phase-frequency response equations of the steady solution to the system under the combined action of parametric excitation and forced excitation are obtained by using the average method, and the stability conditions of the steady solution are obtained based on Lyapunov's first method.

The mid-term outcomes of mobile bearing unicompartmental knee arthroplasty versus total knee arthroplasty in the same patient.

Objective: To compare the mid-term outcomes of unicompartmental knee arthroplasty (UKA) that was performed in one knee and total knee arthroplasty (TKA) performed in the other knee in the same stage.

Methods: This is a retrospective study. A total of 63 patients (126 knees) scheduled for one-stage knee surgery due to osteoarthritis of both knees were selected, and all patients underwent one-stage mobile platform UKA and TKA of the other knee.

Evaluating the role of type 2 diabetes mellitus in rotator cuff tendinopathy: Development and analysis of a novel rat model.

Objective: To establish and validate an intact rotator cuff rat model for exploring the pathophysiological effects of type 2 diabetes on the rotator cuff tendon .

Methods: A total of 45 adult male rats were randomly divided into a control group (n = 9) and type 2 diabetes group (n=36). The rats were sacrificed at 2 weeks (T2DM-2w group, n=9), 4 weeks (T2DM-4w group, n=9), 8 weeks (T2DM-8w group, n=9), and 12 weeks (T2DM-12w group, n=9) after successful modeling of type 2 diabetes.

Cartilaginous Metabolomics Reveals the Biochemical-Niche Fate Control of Bone Marrow-Derived Stem Cells.

Joint disorders have become a global health issue with the growth of the aging population. Screening small active molecules targeting chondrogenic differentiation of bone marrow-derived stem cells (BMSCs) is of urgency. In this study, microfracture was employed to create a regenerative niche in rabbits (n = 9).

Development and validation of a nomogram to predict complications in patients undergoing simultaneous bilateral total knee arthroplasty: A retrospective study from two centers.

Purpose: Complications were significantly increased 30 days after Simultaneous bilateral total knee arthroplasty (SBTKA). In this study, an individualized nomogram was established and validated to predict the complications within 30 days after SBTKA.

Methods: The general data of 861 patients (training set) who received SBTKA in The Affiliated Hospital of Qingdao University between January 1, 2012 and March 31, 2017 were retrospectively analyzed.

LACTB, a Metabolic Therapeutic Target in Clinical Cancer Application.

Serine beta-lactamase-like protein (LACTB) is the only mammalian mitochondrial homolog evolved from penicillin-binding proteins and β-lactamases (PBP-βLs) in bacteria. LACTB, an active-site serine protease, polymerizes into stable filaments, which are localized to the intermembrane space (IMS) of mitochondrion and involved in the submitochondrial organization, modulating mitochondrial lipid metabolism. Cancer pathogenesis and progression are relevant to the alterations in mitochondrial metabolism.

Comparison of Arthroscopic Debridement and Repair in the Treatment of Ellman Grade II Bursal-side Partial-thickness Rotator Cuff Tears: A Prospective Randomized Controlled Trial.

Objective: To compare the effects of arthroscopic debridement and repair in treating Ellman grade II bursal-side partial-thickness rotator cuff tears.

Methods: This is a single-center, prospective, randomized controlled trial. From September 2017 to April 2019, 78 patients underwent arthroscopic debridement (35 patients) or repair (43 patients) due to Ellman grade II bursal-side partial-thickness rotator cuff tears.

A Numerical Study of Slip System Evolution in Ultra-Thin Stainless Steel Foil.

In order to quantitatively describe the effect of the initial grain orientation on the inhomogeneous deformation of 304 austenitic stainless steel foil during tension, a three-dimensional uniaxial tension model was established, based on the crystal plasticity finite element method (CPFEM) and Voronoi polyhedron theory. A three-dimensional representative volume element (RVE) was used to simulate the slip deformation of 304 stainless steel foil with five typical grain orientations under the same engineering strain. The simulation results show that the number and characteristics of active slip systems and the deformation degree of the grain are different due to the different initial grain orientations.