Publications by authors named "Zhonghong Zeng"
Article Synopsis
- * This study analyzed the expression and localization of Entpd3 in the mouse uterus during the estrous cycle using various techniques, finding high levels of Entpd3 during estrus and metestrus, but lower levels during diestrus and proestrus.
- * Hormonal treatments in ovariectomized mice showed that sex steroid hormones like estrogen and progesterone can downregulate Entpd3 expression, suggesting that it may be involved
Article Synopsis
- The study evaluated the safety and effectiveness of IVF/ICSI-ET procedures in women aged 40 and over with singleton pregnancies, comparing results to those from spontaneous conception.
- Findings showed that while some adverse maternal and neonatal outcomes were similar between the two groups, women undergoing IVF/ICSI-ET had higher cesarean rates and maternal ICU admissions but lower birth defects rates.
- The research concluded that IVF/ICSI-ET can be considered relatively safe for older mothers, but advanced maternal age increases risks, necessitating careful monitoring during these procedures.
The relationship between the intake of artificial sweetener (AS) and adverse pregnancy outcomes is under-researched, and existing studies yield inconsistent conclusions. A Mendelian randomization (MR) approach was employed to investigate the causal relationship between the intake of AS and adverse pregnancy outcomes. Instrumental variables related to the exposure phenotype were selected for analysis.
View Article and Find Full Text PDFPregnancy outcomes in women with recurrent implantation failure (RIF) undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI): does treatment with lipiodol flush matter? In this propensity score-matched study, we recruited 966 RIF patients who underwent IVF/ICSI from two tertiary hospitals. These patients were divided into groups based on whether they received lipiodol flush or not. Further stratification was applied to investigate the effect of lipiodol flush on pregnancy outcomes in RIF patients with different cycle type of embryo transferred.
View Article and Find Full Text PDFObjective: To investigate whether operative hysteroscopy in addition to vacuum aspiration for the management of early pregnancy loss effectively increases the success rate of subsequent frozen embryo transfer.
Design: Propensity score-matched cohort study.
Setting: Academic hospital.
Background: The sirtuin family is well recognized for its crucial involvement in various cellular processes. Nevertheless, studies on its role in the human endometrium are limited. This study aimed to explore the expression and localization of the sirtuin family in the human endometrium, focusing on sirtuin 3 (SIRT3) and its potential role in the oxidative imbalance of the endometrium in polycystic ovary syndrome (PCOS).
View Article and Find Full Text PDFBackground: We previously reported that obese mice had significantly high lipid content in embryos, and excessive lipids are detrimental to embryonic development. However, whether maternal obesity has an effect on embryonic vitrification injury and subsequent pregnancy outcomes is still controversial. This study was conducted to clarify the influence of maternal obesity on embryonic vitrification injury and subsequent pregnancy outcomes by in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI).
View Article and Find Full Text PDFBackground: Both in vitro fertilization and embryo transfer (IVF-ET) and intracytoplasmic sperm injection and embryo transfer (ICSI-ET) have been recommended for unexplained primary infertility after recurrent artificial insemination with homologous semen failure (UAIHF), but few studies focused on the safety and efficiency of the IVF/ICSI-ET technique for these patients. In this study, we compared the IVF/ICSI-ET outcomes and perinatal and postnatal complications between UAIHF patients and tubal infertility (TI) patients.
Methods: We conducted a retrospective study of UAIHF and TI patients who underwent IVF/ICSI-ET at Guangxi Reproductive Medical Center, the First Affiliated Hospital of Guangxi Medical University from January 2012 to March 2021.