Effects of pulse parameters on the temperature distribution of a human head exposed to the electromagnetic pulse.

The presence of blood-brain barrier (BBB) is a major obstacle to effectively deliver therapeutics to the central nervous system (CNS); hence, the outcomes following treatment of CNS diseases remain unsatisfactory. Fortunately, electromagnetic pulses (EMPs) provide a non-invasive method to locally open the BBB. To obtain the optimal pulse parameters of EMP-induced BBB opening to ensure the effective delivery of CNS drugs, it is particularly important to measure and assess the effects of pulse parameters on the temperature distribution in the human head exposed to EMPs.

Numerical simulation and analysis of effects of individual differences on the field distribution in the human brain with electromagnetic pulses.

The blood-brain barrier (BBB) opening induced by electromagnetic pulses (EMPs) may be a drug delivery strategy of central nervous system (CNS) diseases. However, the mechanism of EMP-induced BBB opening is still ambiguous. Previous studies have shown the relation between the external field and the extent of BBB permeation (referred to as the effect), while the connection between the internal field and the effect remains unknown.

The Vector Matching Method in Geomagnetic Aiding Navigation.

In this paper, a geomagnetic matching navigation method that utilizes the geomagnetic vector is developed, which can greatly improve the matching probability and positioning precision, even when the geomagnetic entropy information in the matching region is small or the geomagnetic contour line's variety is obscure. The vector iterative closest contour point (VICCP) algorithm that is proposed here has better adaptability with the positioning error characteristics of the inertial navigation system (INS), where the rigid transformation in ordinary ICCP is replaced with affine transformation. In a subsequent step, a geomagnetic vector information fusion algorithm based on Bayesian statistical analysis is introduced into VICCP to improve matching performance further.