Publications by authors named "Zhongfeng Niu"

This study aimed to discuss the clinical value of health education using an animated video for postoperative patients with digital subtraction angiography (DSA)-guided implantable venous access ports. Retrospective study. Based on expert consensus and clinical experience, we created an animated video presenting postoperative health education for patients to watch after infusion port implantation and uploaded it to a multimedia room.

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  • * His blood tests showed normal eosinophil levels despite slight increases in neutrophils and basophils; initial treatment with moxifloxacin helped, but symptoms relapsed after treatment with praziquantel.
  • * Doubling the praziquantel dosage after four months ultimately cured the disease, with the CT's migratory lesions and tunnel signs helping to confirm the parasitic infection diagnosis.
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Objective: To intelligently evaluate the invasiveness of pure ground-glass nodules with multiple classifications using deep learning.

Methods: pGGNs in 1136 patients were pathologically confirmed as lung precursor lesions [atypical adenomatous hyperplasia (AAH) and adenocarcinoma in situ (AIS)], minimally invasive adenocarcinoma (MIA), or invasive adenocarcinoma (IAC). Four different models [EfficientNet-b0 2D, dual-head ResNet_3D, a 3D model combining three features (3D_3F), and a 3D model combining 19 features (3D_19F)] were constructed to evaluate the invasiveness of pGGNs using the EfficientNet and ResNet networks.

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Background: Lymph node metastasis (LNM) is the most common route of metastasis for lung cancer, and it is an independent risk factor for long-term survival and recurrence in patients with non-small cell lung cancer (NSCLC). The purpose of this study was to explore the value of preoperative computed tomography (CT) semantic features in the differential diagnosis of LNM in part-solid nodules (PSNs) of NSCLC.

Methods: A total of 955 patients with NSCLC confirmed by postoperative pathology were retrospectively enrolled from January 2019 to March 2023.

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The split filter CT can filter X-ray beam. Theoretically, the split filter CT not only provides a good low-energy beam, but also provides a more robust CT value. The aim of this study was to compare conventional single-energy computed tomography (SECT) and twin-beam dual-energy (TBDE) CT regarding the quantitative consistency and stabilities of HU measurements at different abdominal organs.

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Rationale And Objectives: Lymphovascular invasion (LVI) plays a significant role in precise treatments of non-small cell lung cancer (NSCLC). This study aims to build a non-invasive LVI prediction diagnosis model by combining preoperative CT images with deep learning technology.

Materials And Methods: This retrospective observational study included a series of consecutive patients who underwent surgical resection for non-small cell lung cancer (NSCLC) and received pathologically confirmed diagnoses.

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  • Intimal sarcoma of the inferior vena cava (IVC) is a rare cancer with vague symptoms and no established treatment protocols.
  • A 54-year-old female patient was diagnosed with this cancer after presenting symptoms like cough and hemoptysis and was found to have multiple lung metastases and cancer in the IVC.
  • Treatment involved initial chemotherapy with gemcitabine and docetaxel, followed by immunotherapy with tislelizumab, resulting in disease stabilization.
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  • The study focuses on creating a CT image segmentation method for adrenal tumors using a combination of an encoder-decoder structure and a Transformer to improve diagnostic accuracy.
  • A total of 182 patients with adrenal metastases were analyzed, with various metrics (like Dice Score and Hausdorff distance) used to assess the effectiveness of the segmentation method.
  • Results indicated that the proposed method achieved high segmentation performance, demonstrating better accuracy compared to existing CNN-based and transformer-based approaches, and effectively generated 3D lesion maps.
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Objectives: The purpose of this study was to establish a risk prediction model for differential diagnosis of pheochromocytomas (PCCs) from lipid-poor adenomas (LPAs) using a grouping method based on tri-phasic CT image features.

Methods: In this retrospective study, we enrolled patients that were assigned to a training set (136 PCCs and 183 LPAs) from two medical centers, along with an external independent validation set (30 PCCs and 54 LPAs) from another center. According to the attenuation values in unenhanced CT (CTu), the lesions were divided into three groups: group 1, 10 HU < CTu ≤ 25 HU; group 2, 25 HU < CTu ≤ 40 HU; and group 3, CTu > 40 HU.

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Objective: To evaluate the risk stratification of 2- to 5-cm gastric stromal tumors (GSTs) by analyzing their clinical and computed tomography (CT) manifestations with the goal of providing imaging evidence for rational selection of surgical methods.

Methods: This study involved 223 patients with pathologically diagnosed GSTs of 2 to 5 cm in diameter. According to the pathological results and malignant risk category, the patients were divided into a low-risk biological behavior group (very low and low risk) and high-risk biological behavior group (intermediate and high risk).

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Background: Intracranial hypotension (IH) is usually associated with cerebrospinal fluid (CSF) leakage and/or CSF hypotension, and epidural blood patch (EBP) therapy has been proven to be effective for treating spontaneous IH and post-dural puncture headaches. Tarlov cysts (TCs) are common lesions of the sacral spine. They have rarely been reported in thoracic locations and are even less common in the posterior mediastinum, which can lead to their misdiagnosis as neurogenic tumors.

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Undifferentiated carcinoma with osteoclast-like giant cells of pancreas (UCOGCP) is a relatively rare tumor worldwide. Its accurate preoperative diagnosis is extremely difficult. Because the mass is usually large and closely related to neighboring structures, it is difficult to locate the tumor and it is often misdiagnosed as pancreatic cancer, neuroendocrine tumor or gastrointestinal stromal tumor.

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The accurate, objective, and reproducible evaluation of tumor response to therapy is indispensable in clinical trials. This study aimed at investigating the reliability and reproducibility of a computer-aided contouring (CAC) tool in tumor measurements and its impact on evaluation of tumor response in terms of RECIST 1.1 criteria.

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Purpose: The aim of this study was to compare the image quality of low virtual monochromatic image (VMI) from the twin-beam dual energy (TBDE) mode to that from the single energy (SE) mode using both standard and low tube voltage acquisition in carotid computed tomography angiography (CTA).

Methods: In this prospective study, 221 patients were imaged using TBDE mode with 120 kV or SE mode with 80/90/120 kV, patient numbers in all groups are equal(n = 55) except in the group using 80 kV SE mode(n = 56). VMIs ranging from 40 to 90 keV with a step of 1 keV were reconstructed from TBDE mode.

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We aimed to build radiomics models based on triple-phase CT images combining clinical features to predict the risk rating of gastrointestinal stromal tumors (GISTs). A total of 231 patients with pathologically diagnosed GISTs from July 2012 to July 2020 were categorized into a training data set (82 patients with high risk, 80 patients with low risk) and a validation data set (35 patients with high risk, 34 patients with low risk) with a ratio of 7:3. Four diagnostic models were constructed by assessing 20 clinical characteristics and 18 radiomic features that were extracted from a lesion mask based on triple-phase CT images.

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Purpose: To evaluate the performance of a dual-energy (DE) calcium removal software based on a modified three-material decomposition algorithm in assessing the stenosis of the internal carotid artery (ICA) in comparison with mixed images using digital subtraction angiography (DSA) as the reference standard.

Methods: Forty-six patients (38 men; 67±8 years old), including 154 calcified ICA segments C1-C2 (59), C3-C5 (63), C6 (24), and C7 (8), were recruited in this retrospective study. Mixed images and virtual non-calcium (VNCa) images using the modified dual-energy computed tomography (DECT) algorithm were reconstructed.

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We sought to investigate the prognostic significance of body composition and weight change during the first 6 months of adjuvant chemotherapy after R0 resection and develop novel nomograms to accurately predict relapse-free survival (RFS) and overall survival (OS). This retrospective study included 190 patients who underwent curative radical gastrectomy for gastric cancer and received adjuvant chemotherapy. The changes in weight and body composition including skeletal muscle index (SMI), subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) were analyzed for 6 months.

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Objective: To investigate the accuracy of the Agatston score obtained with the ultra-high-pitch (UHP) acquisition mode using tin-filter spectral shaping (Sn150 kVp) and a kVp-independent reconstruction algorithm to reduce the radiation dose.

Materials And Methods: This prospective study included 114 patients (mean ± standard deviation, 60.3 ± 9.

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Background: Previous studies have indicated that the changes in body composition during treatment are prognostic in lung cancer. The question which follows is it may be too late to identify vulnerable patients after treatment and to improve outcomes for these patients. In our study, we sought to explore the alterations of body composition and weight before the outset of the antiangiogenic treatment and its role in predicting clinical response and outcomes.

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Purpose: To describe the prognostic value of pulmonary artery (PA) trunk enlargement on the admission of in-hospital patients with severe COVID-19 infection by unenhanced CT image.

Materials And Methods: In-hospital patients confirmed COVID-19 from January 18, 2020, to March 7, 2020, were retrospectively enrolled. PA trunk diameters on admission and death events were collected to calculate the optimum cutoff using a receiver operating characteristic curve.

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Background: Angiomyolipomas (AMLs), belonging to the family of mesenchymal tumors, are considered benign lesions that occur mostly in the kidney or as a part of tuberous sclerosis. Epithelioid AML (EAML) is a rare type of AML that appears to have malignant potential. Extrarenal AMLs usually occur in the liver according to the retrieved literature reports.

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Objective: To investigate the computed tomography (CT) characteristics of adrenal ganglioneuromas (AGNs) and to determine the ability of CT scanning to distinguish between large (>3 cm) and small (≤3 cm) AGNs.

Methods: This retrospective study searched the electronic medical record system of a hospital between January 2008 and July 2019 in order to identify patients with pathologically-confirmed AGNs that underwent three phases of CT scanning. The CT features were compared between large and small AGNs.

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Objective: To identify schwannomas from gastrointestinal stromal tumors (GISTs) by CT features using Logistic Regression (LR), Decision Trees (DT), Random Forest (RF), and Gradient Boosting Decision Tree (GBDT).

Methods: This study enrolled 49 patients with schwannomas and 139 with GISTs proven by pathology. CT features with P < 0.

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Objective: This study was performed to investigate the value of computed tomography (CT) in the differentiation of gastric glomus tumors (GGTs) and small gastric stromal tumors (GSTs).

Methods: Fifty-nine patients with pathologically confirmed GGTs (n = 11) and GSTs (n = 48) from 2006 to 2019 were retrospectively evaluated. All patients' preoperative CT imaging features were analyzed.

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Objectives: To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS.

Methods: Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital between 1 January 2018 and 5 November 2019 who were identified to have odontoid calcification on cervical computed tomography (CT) images. Those who presented with an acute or subacute episode of cervico-occipital pain were defined as CDS, others were non-CDS.

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