Publications by authors named "Zhongduo Ye"
Article Synopsis
- - This study evaluates the effectiveness of bone marrow mesenchymal stem cell-derived exosomes (BMSCs-Exo) in treating spinal cord injuries (SCI) and addresses potential issues when translating results from animal studies to human applications.
- - A systematic review analyzed 30 studies and found that BMSCs-Exo improved motor function by enhancing the BBB score, reducing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, and promoting axonal regeneration while lowering cell death rates.
- - Although BMSCs-Exo showed promise in improving SCI outcomes, the study highlights concerns about biases in animal research that could affect the reliability of these findings.
Background: Osteoporosis (OP) poses a significant clinical challenge with escalating morbidity. This study explores Circ_HECW2 expression in OP patients and its regulatory role in lipopolysaccharide (LPS)-induced osteoblast apoptosis.
Methods: Circ_HECW2 expression in OP patient serum and healthy controls was quantified using RT-qPCR.