Reproductive ecology of the endangered Beal's-eyed turtle, .

The Beal's-eyed turtle () is endemic to southeastern China and endangered due to poaching and habitat loss. Knowledge of ecology is lacking and this study provides baseline information of its reproduction in a natural environment. We studied the reproductive ecology of using X-ray, spool-and-line tracking, and direct observation.

[Inhibitory effect of emodin on the growth of cervical cancer in tumor-transplanted mice and underlying mechanism].

Objective: To observe the effect of emodin on the growth of transplanted U14 cervical cancer cells in mice, and explore its mechanism of anti-tumor.

Methods: The 615-strain mice with U14 cervical cancer cells were randomly divided into 4 groups: control group (DMSO), low-dose emodin group (20 mg/kg), high-dose emodin group (40 mg/kg) and cisplatin group (3 mg/kg). Each group included 10 mice.

Prevalence of human papillomavirus genotypes among women in Hunan province, China.

Objective: Human papillomavirus (HPV) infection has been implicated as a causative factor of cervical cancer. This study aimed to examine HPV genotype distribution and prevalence among women in Hunan province, mid-south China.

Study Design: Cervical samples were collected from 3640 women for cervical cancer screening.

Mesoporous silica nanoparticles with manipulated microstructures for drug delivery.

A range of mesoporous silica nanoparticles (MSNs) with controlled microstructural characteristics were successfully prepared via the binary surfactant templated synthesis approach with varied concentration of triblock copolymer Pluronic F127. The relationship between the MSNs structural evolution and the surfactant concentration was extensively discussed. Ibuprofen (IBU) was loaded as drug model to uncover the in vitro drug releasing kinetics.

Association of cytotoxic T lymphocyte-associated antigen-4 gene haplotype with the susceptibility to gastric cancer.

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) was widely accepted as a pivotal molecule in downregulating T-cell mediated immune responses. In this study we investigated the polymorphisms which would impact the CTLA-4 gene expression and function to assess the association with the risk of gastric cancer. 205 gastric cancer patients and 262 healthy controls were included in the case-control study.

[Combination of antisense human telomerase RNA and antisense human telomerase catalytic subunit inhibits cervical cancer Hela cells growth].

Objective: To investigate the inhibitory effect of combination of antisense human telomerase RNA (anti-hTR) and antisense human telomerase catalytic subunit (anti-hTERT) on proliferation of cervical cancer Hela cell line cultured in vitro.

Methods: Cervical cancer Hela cells were transfected by anti-hTR, anti-hTERT, anti-hTR + anti-hTERT, sense-hTR, sense-hTERT with Oligofectamin reagent. The proliferation activity of cervical cancer Hela cells was determined using methyl thiazolyl tetrazolium (MTT).