Extranodal Rosai-Dorfman disease masquerading as intrathoracic invasive malignancy with ankylosing spondylitis: a case report.

Introduction: Rosai-Dorfman Disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is an uncommon histiocytic disorder. It may be associated with autoimmune diseases, but there are few reports of concurrent ankylosing spondylitis. RDD is typically characterized by massive bilateral and painless cervical lymphadenopathy, which can also involve extranodal sites and constitutional symptoms, but rarely affect the chest cavity.

Career adaptability and career coping styles among Chinese medicine specialty students during the COVID-19: The mediating role of career decision-making self-efficacy.

Over the past decade, the attrition rate of Chinese medical graduates has remained high, and the COVID-19 pandemic has exacerbated this situation. Medicine specialty students are the main force of the future healthcare industry. The career choices and career confidence of those entering the healthcare industry will have a huge influence on the quality of future healthcare provision.

A Semianalytical Model for Advanced Description of Pressure Drop Funnel during Coalbed Methane Production.

Advanced description of pressure drop funnel is crucial in coalbed methane (CBM) production because of dewatering and depressurization methods. Improving the precision of the pressure drop funnel description facilitates obtaining the actual production status and productivity potential, both pivotal for responsible development plans. The study presents a semianalytical model that integrates pressure profiles and material balance equations, incorporating inner and outer boundary conditions, and dynamic reservoir characteristics.

The alterations of functional brain networks and its relationship with sport decision-making and training duration in soccer players across different skill levels.

Studies have indicated that skilled soccer players possess superior decision-making abilities compared to their less-skilled counterparts. However, the underlying neural mechanism for this phenomenon remains incompletely understood. In our investigation, we explored distinctions in the topology of functional brain networks between skilled and less-skilled soccer players.

Novel biomimetic peptide-loaded chitosan nanoparticles improve dentin bonding via promoting dentin remineralization and inhibiting endogenous matrix metalloproteinases.

Objective: This study aims to synthesize novel chitosan nanoparticles loaded with an amelogenin-derived peptide QP5 (TMC-QP5/NPs), investigate their remineralization capability and inhibitory effects on endogenous matrix metalloproteinases (MMPs), and evaluate the dentin bonding properties of remineralized dentin regulated by TMC-QP5/NPs.

Methods: TMC-QP5/NPs were prepared by ionic crosslinking method and characterized by dynamic light scattering method, scanning electron microscopy, transmission electron microscope, atomic force microscope, Fourier transform infrared spectroscopy, and differential scanning calorimetry. The encapsulation and loading efficiency of TMC-QP5/NPs and the release of QP5 were examined.

Unveiling the mechanism of an amelogenin-derived peptide in promoting enamel biomimetic remineralization.

Amelogenin and its derived peptides have exhibited excellent efficacy in promoting enamel biomimetic remineralization. However, little is known about their specific action mechanisms. Herein, by combining experiments and computer simulation, the mechanism of an amelogenin-derived peptide QP5 in regulating enamel biomimetic remineralization is unveiled for the first time.

N-doped carbon sheets supported P-FeO-MoO for freshwater and seawater electrolysis.

Electric-driven freshwater/seawater splitting is an attractive and sustainable route to realize the generation of H and O. Molybdenum-based oxides exhibit poor activity toward freshwater/seawater electrolysis. Herein, we adjusted the electronic structure of MoO by constructing N-doped carbon sheets supported P-FeO-MoO nanosheets (P-FeO-MoO/NC).

Engineering P-FeO-CoP nanosheets for overall freshwater and seawater splitting.

Tailoring surface composition and coordinative environment of catalysts in a nano-meter region often influence their chemical performance. It is reported that CoP exhibits a low dissociation ability of H-OH, originating from the poor desorption of intermediate species. Herein, we provide a feasible method to construct P-FeO-CoP nanosheets through a gas-phase phosphorization process.

Mineralization promotion and protection effect of carboxymethyl chitosan biomodification in biomimetic mineralization.

Biomimetic mineralization emphasizes reversing the process of dental caries through bio-inspired strategies, in which mineralization promotion and collagen protection are equally important. In this study, carboxymethyl chitosan (CMC) was deemed as an analog of glycosaminoglycan for biomimetic modification of collagen, both of the mineralization facilitation and collagen protection effect were evaluated. Experiments were carried out simultaneously on two-dimensional monolayer reconstituted collagen model, three-dimensional reconstituted collagen model and demineralized dentin model.

Performance Evaluation and Action Mechanism Analysis of a Controllable Release Nanocapsule Profile Control and Displacement Agent.

With the acceleration in oilfield developments, reservoir advantage channels have been gradually developed. This has led to ineffective circulation in the oilfield injection system and a significant decrease in production. The profile control and displacement technology of low-permeability and heterogeneous reservoirs are in urgent need of updating.

Fabrication of Ru/WO-WN/N-doped carbon sheets for hydrogen evolution reaction.

Recent experimental analysis indicates WO-based nanostructures exhibit poor hydrogen evolution reactivity, particularly in alkaline medium, arising from the low electron transfer rate. It is imperative to tune the composition and structure of WO to boost the cleavage of H-OH bond. Here, we construct Ru/WO-WN/N-doped carbon sheets (Ru/WO-WN/NC) using m-WO nanosheets as precursors with the aid of RuCl, Tris (hydroxymethyl) aminomethane, and dopamine.

Promoting effect of a calcium-responsive self-assembly β-sheet peptide on collagen intrafibrillar mineralization.

Recently, a synthetic calcium-responsive self-assembly β-sheet peptide ID8 (Ile-Asp-Ile-Asp-Ile-Asp-Ile-Asp) has been developed to serve as the template inducing hydroxyapatite nucleation. The aim of this study was to evaluate the effect of ID8 on intrafibrillar mineralization of collagen making full use of its self-assembly ability. The mineralization experiments were carried out on both bare Type I collagen and fully demineralized dentin samples.

Stroke 120 or FAST (Face, Arm, Speech, Time): Which is Better in Stroke Awareness Promotion for Older Residents Living in Shanghai?

Background: To make a parallel comparison regarding the effectiveness of Stroke 120 and FAST (Face, Arm, Speech, Time) in stroke knowledge promotion among community-living older residents in Shanghai.

Methods: This is a prospective community-based study. Between 1 February 2021 and 31 July 2021, we conducted a community-based stroke education program among older residents living in two communities in Minhang district, Shanghai.

An optimal selection method of wells for secondary fracturing in a single coal seam and its application.

At present, methods including mathematical modeling, physical or numerical simulation, and in-situ monitoring have been generally adopted to determine evaluation parameters for coalbed methane (CBM) wells for secondary fracturing. These conventional methods either entail many assumptions, or some parameters are difficult to obtain, resulting in a certain deviation between the evaluation results and reality, or the application cost is high, preventing the monitoring of each CBM well. In view of this, an evaluation index system for the gas production potential, effective length of cracks formed by fracturing, and supporting length of proppant in cracks was established based on the system theory.

Characterization of phonon thermal transport of TiCTMXene thin film.

Two-dimensional MXene materials with high electrotonic conductivity, good chemical stability, and unique laminar structure show great potential in the field of electrochemistry. In contrast to the widely concerned electrical properties, studies on the thermal properties of MXene materials are very limited. This paper presents a comprehensive analysis of the thermal properties of TiCTMXene thin film.

Expert consensus on resection of chest wall tumors and chest wall reconstruction.

Chest wall tumors are a relatively uncommon disease in clinical practice. Most of the published studies about chest wall tumors are usually single-center retrospective studies, involving few patients. Therefore, evidences regarding clinical conclusions about chest wall tumors are lacking, and some controversial issues have still to be agreed upon.

Age-Related Disparities in Stroke Knowledge Among Community Older Adults.

This study aimed to investigate the disparities in stroke knowledge between older adults and the oldest old. Family physicians conducted a cross-sectional survey through face-to-face interviews with the older and oldest old adults of two suburban communities in the Minhang district, Shanghai between October 1, 2020, and November 30, 2020. All participants were classified as oldest old (age ≥80 years) and older adults (age 60-79 years).

Poor awareness of stroke educational tools among older adults in China.

Background: Stroke 1-2-0 and FAST (Face, Arm, Speech, Time) are two popular stroke educational tools that have been used in many stroke promotion campaigns. However, few researchers have investigated awareness of these tools among older adults in communities.

Methods: This study was a cross-sectional survey of community-living older adults.

Distribution Characteristics of C-N-S Microorganism Genes in Different Hydraulic Zones of High-Rank Coal Reservoirs in Southern Qinshui Basin.

Microbial decomposition of carbon and biogenic methane in coal is one of the most important issues in CBM exploration. Using metagenomic technologies, the microbial C-N-S functional genes in different hydraulic zones of high-rank coal reservoirs were systematically studied, demonstrating the high sensitivity of this ecosystem to hydrodynamic conditions. The results show that the hydrodynamic strength of coal reservoir #3 in the Shizhuangnan block gradually weakened from east to west, forming a transitional feature from a runoff area to a stagnant area.

Panicle Apical Abortion 3 Controls Panicle Development and Seed Size in Rice.

Background: In rice, panicle apical abortion is a common phenomenon that usually results in a decreased number of branches and grains per panicle, and consequently a reduced grain yield. A better understanding of the molecular mechanism of panicle abortion is thus critical for maintaining and increasing rice production.

Results: We reported a new rice mutant panicle apical abortion 3 (paa3), which exhibited severe abortion of spikelet development on the upper part of the branches as well as decreased grain size over the whole panicle.

Lactate Modulates Cellular Metabolism Through Histone Lactylation-Mediated Gene Expression in Non-Small Cell Lung Cancer.

Lactate has been observed to fuel TCA cycle and is associated with cancer progression in human lung cancer, the leading cause of cancer deaths worldwide, but the effect of lactate on lung cancer metabolism is rarely reported. In this study, disordered metabolism in non-small cell lung cancer was demonstrated by increased G6PD and SDHA protein levels immunofluorescence, and up-regulated lactate dehydrogenase was found to be associated with poor prognosis. Then flow cytometry and Seahorse XFe analyzer were utilized to detect the effect of lactate on glycolysis and mitochondrial function in non-small cell lung cancer cells.

STK1p as a prognostic biomarker for overall survival in non-small-cell lung carcinoma, based on real-world data.

Aim: A prospective investigation of serum thymidine kinase 1 concentration (STK1p) was performed to evaluate its prognostic value in patients with non-small-cell lung carcinoma (NSCLCs).

Patients & Methods: The STK1p values of 127 patients were determined by an enhanced chemiluminescent dot blot assay. The patients were recruited from March 2011 to December 2017.

Quantitative optimization of drainage strategy of coalbed methane well based on the dynamic behavior of coal reservoir permeability.

The development of coalbed methane (CBM) is not only affected by geological factors, but also by engineering factors, such as artificial fracturing and drainage strategies. In order to optimize drainage strategies for wells in unique geological conditions, the characteristics of different stages of CBM production are accurately described based on the dynamic behavior of the pressure drop funnel and coal reservoir permeability. Effective depressurization is achieved by extending the pressure propagation radius and gas desorption radius to the well-controlled boundary, in the single-phase water flow stage and the gas-water flow stage, respectively, with inter-well pressure interference accomplished in the single-phase gas flow stage.

Chitosan-Based Biomimetically Mineralized Composite Materials in Human Hard Tissue Repair.

Chitosan is a natural, biodegradable cationic polysaccharide, which has a similar chemical structure and similar biological behaviors to the components of the extracellular matrix in the biomineralization process of teeth or bone. Its excellent biocompatibility, biodegradability, and polyelectrolyte action make it a suitable organic template, which, combined with biomimetic mineralization technology, can be used to develop organic-inorganic composite materials for hard tissue repair. In recent years, various chitosan-based biomimetic organic-inorganic composite materials have been applied in the field of bone tissue engineering and enamel or dentin biomimetic repair in different forms (hydrogels, fibers, porous scaffolds, microspheres, etc.