Postoperative peritumoral edema is correlated with the prognosis in intracranial meningioma with preoperative peritumoral edema.

Preoperative peritumoral edema (PTE) in intracranial meningiomas is known to be a risk factor for postoperative recurrence. However, there are two groups: those in which preoperative PTE remains and those in which preoperative PTE receded after tumor removal. We aimed to investigate whether postoperative PTE could improve the prediction of prognosis of meningioma with preoperative PTE.

Development and validation of health-oriented personal evaluation for the community-dwelling older person based on the International Classification of Functioning, Disability and Health.

Background: The International Classification of Functioning, Disability and Health (ICF) offers a standardized international terminology to operationalize function management across multiple domains, but the summary score of the ICF qualifier scale provides limited information on the comparison of personal abilities and functioning difficulties.

Objectives: To enhance the interpretative power of the ICF-based Health-oriented Personal Evaluation for the community-dwelling older person (iHOPE-OP) scale through the implementation of the item response theory (IRT) modelling.

Methods: This cross-sectional, multi-centre study administrated 161 ICF categories (58 on body functions, 15 on body structures, 60 on activities or participation and 28 on environmental factors) to evaluate the functional level of 338 older citizens (female = 158, male = 180) residing in community or supportive living facilities.

Transcutaneous auricular vagus nerve stimulation with task-oriented training improves upper extremity function in patients with subacute stroke: a randomized clinical trial.

Background: Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a promising brain stimulation modality in poststroke upper extremity rehabilitation. Although several studies have examined the safety and reliability of taVNS, the mechanisms underlying motor recovery in stroke patients remain unclear.

Objectives: This study aimed to investigate the effects of taVNS paired with task-oriented training (TOT) on upper extremity function in patients with subacute stroke and explore the potential underlying mechanisms.

Haemophilia item bank based on International Classification of Functioning, Disability and Health: a systematic review.

Background And Objectives: Haemophilia comprises a continuum of blood disorders that often include joint and muscular dysfunction, which may lead to a constellation of activity limitations and participation restrictions. However, there is scant research incorporating functional assessment scales into the common language provided by the International Classification of Functioning, Disability and Health (ICF). This study aims to identify the ICF categories to include in an item bank of functioning aspects relevant for haemophilia.

Network analysis of internet addiction and sleep disturbance symptoms.

Background: Internet addiction (IA) is a behavioral addiction to problematic internet use. IA is associated with poorer sleep quality. Few studies to date, however, have explored the interactions between symptoms of IA and symptoms of sleep disturbance.

ICF-Based simple scale for children with cerebral palsy: Application of Mokken scale analysis and Rasch modeling.

Children with cerebral palsy (CP) are faced with long-term dysfunction. The International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY) has been proposed but the complicated procedure limits the feasibility of clinical application and the exploration of health degrees. This study was aimed to establish a Mokken scale based on the ICF-CY for CP, and then to estimate psychometric properties through the derived Rasch model.

Activity and participation in haemophiliacs: Item response modelling based on international classification of functioning, disability and health.

Background And Objectives: There is scant research investigating the user-friendly functional assessment tool conceptualized by the International Classification of Functioning, Disability and Health (ICF) among persons with haemophilia (PWH). This study aims to accomplish two goals: (1) quantifying comprehensive functioning measures of haemophilia through Item Response Theory (IRT); (2) discussing patient-centred care based on the Wright map of personal ability and item difficulty.

Methods: A cross-sectional study was carried out in 70 PWH (mean age, 33.

Pure and non-pure meningioangiomatosis of 36 Chinese patients: an analysis of clinical presentation, diagnosis, histopathology and prognosis.

Meningioangiomatosis (MA) is a disease that is extremely rarely reported. Sporadic MA is occasionally combined with meningioma or other lesions (identified as non-pure MA). This retrospective study investigated the difference between pure MA and non-pure MA by exploring clinical manifestations, histopathology characteristics, and outcomes of MA after surgery.

Simplified Post-stroke Functioning Assessment Based on ICF Dichotomous Mokken Scale Analysis and Rasch Modeling.

Purpose: This study aims to accomplish two tasks for (ICF) application among persons with stroke: (1) to make an ICF tool for measuring personal abilities with simplified assessment operations; (2) to quantitatively evaluate ICF categories for being functioning rather than being disabled.

Methods: A total of 130 inpatients with stroke convenience sampling were evaluated by the extended comprehensive ICF core set for stroke, modified Rankin scale, and modified Barthel index (MBI). This study investigated the responses to 118 stroke-related ICF items (59 items in b and d domains individually) using Mokken scale analysis followed with Rasch modeling.

Imbalanced Gamma-band Functional Brain Networks of Autism Spectrum Disorders.

Resting gamma-band brain networks are known as an inhibitory component in functional brain networks. Although autism spectrum disorder (ASD) is considered as with imbalanced brain networks, the inhibitory component remains not fully explored. The study reported 10 children with ASD and 10 typically-developing (TD) controls.

Transcriptional Characteristics of -Wild Type Glioma Subgroups Highlight the Biological Processes Underlying Heterogeneity of -Wild Type WHO Grade IV Gliomas.

-wild type diffuse gliomas, which have a poorer prognosis than their -mutant counterparts, are also accompanied with high heterogeneity. Here, we aimed to identify the key biological processes associated with the three groups of -wild type diffuse gliomas in 323 patients. By The Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW) update 3 recommendation, the three groups are Group A, diffuse astrocytic glioma, World Health Organization (WHO) grade II/III; Group B, diffuse astrocytic glioma, with one (or more) of the three genetic alterations: promoter mutation, gene amplification, gain of chromosome 7 combined with loss of chromosome 10, WHO grade IV; and Group C, glioblastoma, WHO grade IV.

Hyoid-complex elevation and stimulation technique restores swallowing function in patients with lateral medullary syndrome: Two case reports.

Background: A swallowing disorder may occur following a brainstem stroke, especially one that occurs in the swallowing centers. Lateral medullary syndrome (referred to as LMS), a rare condition in which a vascular event occurs in the territory of the posterior inferior cerebellar artery or the vertebral artery, has been reported to lead to more severe and longer lasting dysphagia.

Case Summary: We report two patients with dysphagia due to LMS and propose a novel technique named hyoid-complex elevation and stimulation technique (known as HEST).

[Application of intraoperative ultrasound combined with neuronavigation for resection of intracranial cavernous malformations in minimally invasive neurosurgery].

Objectives: To analyze the reliability and clinical value of intraoperative ultrasound combined with neuronavigation for resection of intracranial cavernous malformations.

Methods: From January 2007 to December 2009, 40 cases of intracranial cavernous malformations were operated under the application of intraoperative ultrasound combined with neuronavigation. There were 18 male and 22 female, aged 18 to 58 years, with a mean age of 34.

[Perspectives of network thinking and network analysis applied on meridians and collaterals researches].

The retrospective method of literatures was adopted and the epistemology of network thinking was integrated with the methodology of network analytic techniques so that the researches of meridian and collateral could be conducted in the new view of complex networks. The results indicate that meridian and collateral could be regarded as the complex networks composed of acupoints and meridians. The thinking and the methods of network analysis are ongoing to be applied to the paradigm of the analysis on meridian and collateral and it is expected that the paradigm could generate profound impacts on understanding the substance of meridian and collateral as well as on guiding clinical practice.

[Pattern of acupoint selection based on complex network analysis technique].

To analyze the global structural models of point prescription in acupuncture therapy, and to provide new insights for acupoint selection based on syndrome differentiation. Taking prescriptions in the commonly used textbooks as the resources, a directed network of point prescription according to syndrome differentiation was constructed. The network was visualized with Pajek 1.

[Microsurgical treatment of adult craniopharyngiomas in 156 cases].

Objective: To explore the clinical features, surgical approaches and outcomes of craniopharyngioma in adults.

Methods: A total of 156 cases of adult craniopharyngioma underwent microsurgery at our hospital were retrospectively reviewed and classified into four types according to the location of tumor relative to sellar diaphragm and the third ventricle. They were divided into four groups: intrasellar type (n = 6), suprasellar & extraventricular type (n = 59), intraventricular type (n = 63) and mixed type (n = 28).

Comparative proteome analysis of neural retinas from type 2 diabetic rats by two-dimensional electrophoresis.

Purpose: The purpose of this study was to isolate, identify, and analyze diabetes-related protein changes that occur in neural retinas in vivo.

Methods: Total proteins were extracted from neural retinas of normal and 8-weeks diabetic Sprague-Dawley (SD) rats and separated by two-dimensional gel electrophoresis (2-DE). Some protein spots exhibiting statistically significant variations (p < 0.

[Mesial temporal lobe anatomy and its relationships with surrounding structures].

Objective: To explore the anatomy of mesial temporal lobe and the relationships between the mesial temporal lobe and its surrounding structures.

Methods: Twenty formalin-fixed adult cadaveric heads after perfusion of the arteries and veins with colored latex were studied under microscope, and photographs were taken.

Results: The hippocampus, fimbria, amygdala and choroidal fissure constituting the mesial temporal lobe were intraventricular structures, and uncus, parahippocampal gyrus, and dentate gyrus were extraventricular structures.

[Surgical outcomes of different approaches for mesial temporal lobe gliomas].

Objective: To analyze the surgical outcomes of different approaches for mesial temporal lobe gliomas.

Methods: Microsurgery was performed via trans-sylvian, trans-temporal, or subtemporal approaches on 62 patients with mesial temporal lobe gliomas, 33 with localized tumors within the mesial temporal structures (type A), 19 in anterior portion (type A1), and 14 extending to posterior portion (type A2); 19 patients with multicompartmental tumors involving the mesial temporal lobe, insular lobe, and posterior frontorbital gurus (type B); 14 patients with tumors involving the temporal pole and lateral areas of the temporal horn (type C); and 6 patients with tumors infiltrating the brain stem, basal nuclei and thalamus (type D).

Results: Trans-sylvian approach was performed in 25 cases of which total tumor removal was achieved in 14 cases, subtotal removal in 6 cases, and gross removal in 5 cases.