An evaluation of 20-year survival of radiofrequency ablation for hepatocellular carcinoma as first-line treatment.

Objectives: To evaluate the changes in clinical characteristics, overall survival (OS), and progression-free survival (PFS) by investigating a 20-year cohort of patients with HCC who underwent RFA treatment.

Methods: From 2000 to 2020, 505 consecutive patients with HCC underwent ultrasound-guided percutaneous RFA as first-line therapy at a tertiary cancer hospital. We divided the cohort according to the time when hepatitis-B antiviral therapy was covered by national medical insurance coverage (early 2011), including the first decade (2000-2010) and second decade (2011-2020).

Epidemiological and clinical features of functional dyspepsia in a region with a high incidence of esophageal cancer in China.

Background: Functional dyspepsia (FD) has rarely been investigated in areas with a high prevalence of esophageal squamous cell carcinoma (ESCC). This study aims to reveal the epidemiological and clinical features of FD and organic dyspepsia (OD) in such a population.

Methods: A middle-aged and elderly population-based study was conducted in a region with a high incidence of ESCC.

Family history of esophageal cancer modifies the association of serum lipids and malignant esophageal lesions: a nested case-control study from the "Endoscopic Screening for Esophageal Cancer in China" trial.

Background: The association of lipids and cancer has varied greatly among different cancer types, lipid components and study populations. This study is aimed to investigate the association of serum lipids and the risk of malignant lesions in esophageal squamous epithelium.

Methods: In the "Endoscopic Screening for Esophageal Cancer in China" (ESECC) trial, serum samples were collected and tested for total cholesterol (TC), triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol at the time of subject enrollment.

A population-based survey of gastroesophageal reflux disease in a region with high prevalence of esophageal cancer in China.

Background: The exact relationship between gastroesophageal reflux disease (GERD) and esophageal squamous cell cancer (ESCC) is far from clarification. The aim of this study was to investigate the epidemiology of GERD in a region with high prevalence of ESCC in China.

Methods: A population-based, cross-sectional study was conducted in a high ESCC prevalent area, Anyang, Henan, China.

[Prevalence and risk factors for hepatitis B in Hua County, Henan Province].

Objective: To determine the epidemiological characteristics and associated risk factors of hepatitis B surface antigens (HBsAg) prevalence in rural areas of Hua County, Henan Province, and to provide scientific evidence for Hepatitis B prevention and control in local areas.

Methods: On the basis of an ongoing esophageal cancer cohort study in rural Anyang, a total of 5 104 subjects aged 25-65 years were clustered and selected from 5 targeted villages for this study in rural areas of Hua County, Henan Province. HBsAg was detected in their blood samples and a questionnaire was completed by all the subjects in a manner of one-on-one interview.

[Waist circumference distribution of Chinese school-age children and adolescents].

Objective: To study the distribution of waist circumference (WC) in a representative group of Chinese children for establishing the Chinese WC cut-off points.

Methods: Cross-sectional data obtained from 15 mainland provinces and Hong Kong were collected. There were 178 865 children and adolescents, aged 7 - 18 years-old in total.

[Cloning and phylogenetic analysis of low-molecular-weight glutenin subunit genes at Glu-B3 locus in common wheat relative species].

The common wheat relative species are important germplasm for wheat breeding. In the present study, novel allelic variants at Glu-B3 locus were cloned to provide gene resources for wheat quality improvement. Four Glu-B3-locus specific primer sets LB1F/LB1R, LB2F/LB2R, LB3F/LB3R, and LB4F/LB4R were employed to isolate novel allelic variants of GluB3-1, GluB3-2, GluB3-3, and GluB3-4 from seven common wheat relative species, i.

Waist circumference distribution of Chinese school-age children and adolescents.

Background: Waist circumference (WC), a proxy measure of central body fat, is a better predictor than overall body fat for cardiovascular risk factors in both adults and children. WC cutoffs have been established in many countries, but the national WC reference has not been developed in China.

Objective: To study the distribution of WC in a representative group of Chinese children for establishing Chinese WC cutoff points.

[Investigation of HIV/AIDS related knowledge and attitude among 6,487 high school students].

Objective: To investigate HIV/AIDS related knowledge and attitude among high school students in China, and to preliminarily evaluate the effects of the special HIV/AIDS prevention education programme.

Methods: A total of 6487 high school students from 24 high schools of Beijing, Zhengzhou and Tangshan were investigated by using questionnaire, among which, 6487 students completed the questionnaire (96.08%).

[Effects of ascorbic acid and citric acid on iron bioavailability in an in vitro digestion/ Caco-2 cell culture model].

Objective: To study the effects of ascorbic acid and citric acid on iron bioavailability using an in vitro digestion/Caco-2 cell culture model and evaluate the validity of this cell model.

Methods: This model combined in vitro digestion technique with Fe uptake by Caco-2 cells by utilizing an inserted ring attached to a dialysis membrane to simulate the gastrointestinal environment to allow simultaneous food digestion and uptake processes. Ferritin formation in the Caco-2 cells was measured as the indicator of Fe uptake by exposing Caco-2 cells to the digests containing Fe plus ascorbic acid or citric acid.

[Secular growth trends in the Chinese urban youth and its implications on public health].

Objective: To analyze the secular growth trends of the Chinese urban youth from 1979 to 2005, in order to make national intervention strategies and measures to improve their physical fitness and health.

Methods: Subjects were sampled from 16 provincial-capital cities in China. They were all Han primary and secondary school students aged 7 to 18 years.