Publications by authors named "Zhong-Xiu Wang"

Aims: To investigate the characteristics of dynamic cerebral autoregulation (dCA) after intravenous thrombolysis (IVT) and assess the relationship between dCA and prognosis.

Methods: Patients with unilateral acute ischemic stroke receiving IVT were prospectively enrolled; those who did not were selected as controls. All patients underwent dCA measurements, by quantifying the phase difference (PD) and gain, at 1-3 and 7-10 days after stroke onset.

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Article Synopsis
  • - The study aimed to identify factors linked to poor clinical outcomes in patients with acute ischemic stroke who underwent endovascular therapy, analyzing 265 cases from Jilin University between 2016 and 2019.
  • - Results indicated that successful revascularization occurred in 84.5% of cases, but only 46% had a good prognosis after 90 days, with independent risk factors for poor outcomes being diabetes, tandem occlusion, high NIHSS score at admission, and general anesthesia.
  • - The findings suggest that neurointerventionalists should consider these risk factors when making clinical decisions for acute ischemic stroke patients to improve outcomes.
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: Intravenous thrombolysis (IVT) therapy is currently one of the best medical treatments available for patients with acute ischemic stroke. Studies have shown that blood pressure (BP) changes in patients treated with IVT are significantly correlated with prognosis. : Our study aimed to determine the relationship between BP changes during recombinant tissue plasminogen activator (rt-PA) infusion and the 3-month prognosis evaluated using the modified Rankin Scale (mRS) and determine the factors influencing BP changes during rt-PA infusion.

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Background And Purpose: Modified Thrombolysis in Cerebral Infarction (mTICI)2b/3 has been considered the criterion for successful reperfusion in endovascular treatment. This study aimed to compare the therapeutic safety and efficacy of mTICI2b and mTICI3 recanalization, and to analyze the factors related to outcomes in everyday clinical practice.

Materials And Methods: This is a single-center retrospective analysis of 224 patients who underwent successful thrombectomy (achieving a mTICI score ≥2b).

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