Publications by authors named "Zhong-Siang Wu"
Article Synopsis
- The study discusses using iodoacetamide (IAA) and N-methyliodoacetamide (MIAA) as labeling agents for measuring proteins via MALDI-MS, which simplifies the process compared to isotope labeling.
- These reagents specifically target cysteine residues in proteins during denaturation and digestion, showing effective dynamic ranges and high correlation coefficients for quantifying proteins like lysozyme, transferrin, and BSA.
- The labeling method is particularly advantageous for relative quantification in cases where the chromatographic isotope effect isn't a significant issue.
