Publications by authors named "Zhong-Qi Mao"

Introduction: The dissection of the preperitoneal space is performed using a monopolar instrument to prevent bleeding in laparoscopic transabdominal preperitoneal hernia repair (TAPP). It may also cause energy injuries and nerve damage.

Aim: To assess the effectiveness and safety of dissection of the preperitoneal space without electrocoagulation (DPSWE) in TAPP throughout the process.

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Introduction: For an indirect inguinal hernia (IIH), it is a challenge to repair the internal inguinal ring (IIR) with self-tissue reconstruction in laparoscopic repair.

Aim: To evaluate the efficacy and safety of covering the IIR with the lateral umbilical fold (LUF) combined with patch repair in laparoscopic indirect inguinal hernia repair.

Material And Methods: Patients with IIH treated by trans-abdominal preperitoneal (TAPP) hernia repair at the Department of General Surgery, Shanghai Public Health Clinical Centre between September 2019 and March 2021 were retrospectively analyzed.

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Background: There are few comparative studies of the clinical outcomes after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG). The aim of the study was to compare diabetes- and metabolic disorder-related outcomes following RYGB and SG, based on data for matched participants.

Methods: This was a retrospective matched study using data from 2011-2018.

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Background: NLR family CARD domain containing 5 (NLRC5) is involved the initiation and progression of several cancers. However, its role in hepatocellular carcinoma (HCC) is still unclear. This study aimed to explore the expression, clinical significance, and regulated gene sets of NLRC5 in HCC.

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  • Gastric cancer is the fourth most common cancer globally and significantly contributes to cancer-related deaths, with platelets playing a crucial role in its progression.
  • The study analyzed 168 patients with resectable gastric cancer and found that those with elevated mean platelet volume (MPV) levels had worse survival rates and more severe disease features compared to healthy individuals.
  • The research concluded that measuring MPV can be a valuable diagnostic and prognostic tool in evaluating patients with resectable gastric cancer, as changes in MPV post-surgery were linked to improved survival outcomes.
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  • - The study examined the usefulness of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in predicting how patients with advanced gastric cancer respond to chemotherapy and their overall survival.
  • - Results showed that patients with low baseline NLR and PLR had better tumor characteristics and improved responses to chemotherapy, while those with high levels had worse survival rates.
  • - Changes in NLR and PLR after chemotherapy also correlated with treatment effectiveness and prognosis, indicating that monitoring these ratios can help predict outcomes for patients with unresectable gastric cancer.
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  • Gastric cancer is a leading cause of cancer-related deaths, particularly in China, and is known to be driven by inflammation, prompting a study on systemic inflammatory response (SIR) markers like the platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) for early diagnosis and prognosis.
  • The study analyzed 162 patients with resectable gastric cancer, categorizing them based on pre-operative PLR and NLR values, and examining changes in these ratios post-surgery.
  • Results showed that lower pre-operative PLR and NLR levels indicated better tumor characteristics and were linked to improved overall survival and disease-free survival outcomes, suggesting these measurements could be valuable in clinical assessment.
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Laparoscopic Roux-en-Y gastric bypass (LRYGB) has become the gold standard operation for morbid obesity, because effects of LRYGB are quick and lasting. However, there are many potential risks due to the operative complexity and long learning curve. There are early and late complications after LRYGB.

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Objective: To evaluate the efficacy of laparoscopic Roux-en-Y gastric bypass (LRYGB) in the treatment of type 2 diabetes mellitus(T2DM).

Methods: Clinical data of 62 cases undergoing LRYGB from May 2010 to October 2011 were analyzed retrospectively.

Results: LRYGB was completed in 58 patients successfully.

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