Alisma Shugan Decoction attenuates hepatic fibrosis and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis.

Background: Over the years, Alisma Shugan Decoction (ASD), because of its potent anti-inflammation activity, has been used in traditional Chinese medicine (TCM) for treatment of many inflammation-associated disorders including those of the heart, blood vessel and brain.

Methods: Herein, we examined the probable therapeutic effect of ASD in carbon tetrachloride (CCl4)-induced liver injury and fibrosis mice models.

Results: Our results demonstrate that ASD dose-dependently reduced the fibrosis-related increased collagen deposition secondary to liver tissue exposure to CCl4.

[Study on HPLC fingerprint of ethanol extract of Phellinus igniarius].

Objective: To establish the HPLC fingerprint of ethanol extract of Phellinus igniarius ( EEPI), and to evaluate its quality.

Methods: Adopted 0.2% phosphoric acid -methanol as mobile phase with a SHISEIDO CAPCELL PAK C18 column (250 mm x 4.