Glycosparvine A, a new indole alkaloid from the leaves of .

In the course of our ongoing search for biologically active compounds from medicinal plant, the ethyl acetate extract from the leaves of (Rutaceae) was investigated. Six compounds including a new indole alkaloid, glycosparvine A (), and five previously known metabolites (-) were identified. The structure of the new compound () was unambiguously elucidated by spectroscopic analyses, including 1D/2D NMR spectroscopy and HRESIMS.

Bioactive sulfur-containing amides from the leaves of .

Two new sulphur-containing amides, glylucidamides C-D (-), along with twelve known analogues (-) were isolated and characterised from the leaves of . The chemical structures of and were elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons their data with those reported in the literatures. All new compounds were evaluated for their anti-inflammatory activities examining the inhibitory activity on nitric oxide (NO) production induced by lipopolysaccharide in mouse macrophage RAW 264.

Structurally diverse sulphur-containing amides from Glycosmis craibii with their potential antiproliferative activities.

Fourteen new sulphur-containing amides, glycocramides A-N (1-14), as well as nine known analogues (15-23) were isolated and characterized from Glycosmis craibii Tanaka. The chemical structures of new sulphur-containing amides 1-14 were ambiguously elucidated by extensive spectroscopic methods, while the known compounds 15-23 were identified by the comparison of their experimental spectral data with those described data in the literatures. The antiproliferative effects of all isolated sulphur-containing amides were evaluated in vitro.

Cyprotuoside C and Cyprotuoside D, Two New Cycloartane Glycosides from the Rhizomes of Cyperus rotundus.

Cyprotuoside C (1) and cyprotuoside D (2), two new cycloartane glycosides were isolated from the ethanol extract of the rhizomes of Cyperus rotundus. Their structures were identified as 24R-9,10-seco-cycloartan-1(10),9(11)-dien-3β,7β,24,25-tetraol 3-O-β-D-xylopyranosyl-(1→4)-[α-L-arabinopyranosyl-(1→6)]-β-D-glucopyranosyl-25-O-β-D-glucuronide (1) and 9,10-seco-cycloartan-1(10),9(11),23(24)-trien-3β,7β,25-triol 3-O-β-D-xylopyranosyl-(1→4)-{α-L-arabinopyranosyl-(1→6)-[α-L-rhamnopyranosyl-(1→2)]}-β-D-glucopyranosyl-25-O-β-D-glucuronide (2) by spectroscopic methods.

Three New Polyphenolic Acids from the Leaves of Eucalyptus citriodora with Antivirus Activity.

Six polyphenolic acids (1-6), including the three new compounds citriodolic acids A, B, and C (1-3), were isolated from the leaves of Eucalyptus citriodora. Their structures were elucidated by spectroscopic methods including one dimensional (1D)- and 2D-NMR, high-resolution electrospray ionization (HR-ESI)-MS, and circular dichroism (CD). The potential antivirus activity against respiratory syncytial virus (RSV) of all the isolated compounds was evaluated.

New cycloartane glycosides from the rhizomes of Cyperus rotundus and their antidepressant activity.

Two new cycloartane glycosides, cyprotusides A (1) and B (2), were isolated from the rhizomes of Cyperus rotundus. Their chemical structures were elucidated on the basis of IR, MS, NMR spectroscopic analyses coupled with chemical degradation. The potential antidepressant activity of the two compounds was evaluated.

New Iridoid Glycosides with Antidepressant Activity Isolated from Cyperus rotundus.

Based on bioactive screening results, two new iridoid glycosides, named rotunduside G (1) and rotunduside H (2), were isolated from the rhizomes of Cyperus rotundus, together with four known ones, negundoside (3), nishindaside (4), isooleuropein (5) and neonuezhenide (6). Their structures were elucidated on the basis of spectroscopic methods and from literature values. In mice models of despair, 1 and 2 showed significant antidepressant activity.

A new triterpene saponin from the roots of Ilex pubescens.

A new triterpene saponin, ilexoside P (1), along with three known triterpene saponins, ilexoside O (2), ilexsaponin B3 (3) and ilexpublesnin A (4) was isolated from the roots of Ilex pubescens. Their chemical structures were elucidated on the basis of UV, IR, MS, and NMR spectroscopic analyses coupled with chemical degradation. In addition, the xanthine oxidase (XOD) inhibitory activity of the isolated saponins was reported.

Steroidal and phenolic glycosides from the bulbs of Lilium pumilum DC and their potential Na+/K+ ATPase inhibitory activity.

A new steroidal saponin, named pumilum A (1), and a new phenolic glycoside, threo-1-(4'-hydroxy-2'-methoxyphenyl)-2-(2",4"-dihydroxyphenyl)-1,3-propanediol-4'-O-β-D-glucopyranoside (7) were isolated from the methanolic extract of the bulbs of Lilium pumilum DC, along with five known steroidal saponins. Their chemical structures were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR techniques and chemical methods. In addition, the inhibitory activity of all the isolates on Na(+)/K(+) ATPase was evaluated.

[Study on extraction and purification techniques and free radical scavenging activity of total flavonoids from Fissistigma oldhamii].

Objective: To optimize the extraction and purification techniques of total flavonoids in Fissistigma oldhamii. The scavenging activity to DPPH of the total flavonoids and the extraction were studied in vitro.

Methods: By orthogonal design, we investigated the effects of concentration of ethanol, temperature, ratio of solid to liquid and time of extraction on the total flavonoids extraction rate.

4,4'-[4,4'-Sulfonyl-bis-(p-phenyl-ene-oxy)]dibutanoic acid.

In the title compound, C(20)H(22)O(8)S, the dihedral angle between the two benzene rings is 81.6 (3)°. The benzene-connected portions of the alk-oxy substituents are almost coplanar with their respective rings [C-C-O-C torsion angles of 174.

[Studies on the aporphine alkaloids from Fissistigma oldhamii (Hemsl.) Merr].

Objective: To study aporphine alkaloids from Fissistigma oldhamii (Hemsl.) Merr. which is a characteristic plant of Guangxi.