Publications by authors named "Zhong-Lei Lu"
Effect of colorectal cancer stem cells on the development and metastasis of colorectal cancer.
World J Gastrointest Oncol
November 2024
Article Synopsis
- The text discusses the role of tumor-associated macrophages (TAMs) in enhancing the effectiveness of immune checkpoint inhibitors (ICIs) for treating colorectal cancer.
- It highlights that while ICIs can activate immune responses against tumors, the effectiveness varies among patients based on the interactions between TAMs and the tumor environment.
- By understanding and manipulating TAMs, researchers hope to overcome resistance to ICIs and improve treatment outcomes for colorectal cancer patients.