Publications by authors named "Zhong-Heng Gwo"
Article Synopsis
- A series of 1,4-naphthoquinone derivatives were synthesized to study how their hydrophobicity affects anticancer activity against five different human cancer cell lines.
- Among these compounds, 2-hydroxy-3-farnesyl-1,4-naphthoquinone (11a) was identified as particularly effective, demonstrating significant cytotoxicity against HT-29 colon cancer cells.
- The compound 11a induced apoptosis in HT-29 cells, as shown through various assays, and effectively inhibited the proliferation of these cancer cells, indicating its potential as a strong anticancer agent.
