Publications by authors named "Zhong-Han Zhang"

Article Synopsis
  • - The study investigates the increasing burden of inflammatory bowel disease (IBD) among children and adolescents globally over the past 30 years, analyzing data from 204 countries using the Global Burden of Disease database.
  • - Findings indicate a significant rise in the prevalence (0.15% annual increase) and incidence (22.78% increase from 1990 to 2019) of IBD, while disability-adjusted life years (DALYs) and mortality have decreased (56.17% decrease in mortality).
  • - A correlation was found where high-quality healthcare systems are associated with higher IBD prevalence and incidence rates but better health outcomes, as indicated by lower DALYs and mortality rates.
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Background: Cancer patients often exhibit chemotherapy-associated changes in serum lipid profiles, however, their prognostic value before and after adjuvant chemotherapy on survival among non-small-cell lung cancer (NSCLC) patients is unknown.

Methods: NSCLC patients undergoing radical resection and subsequent adjuvant chemotherapy from 2013 to 2017 at Sun Yat-sen University Cancer Center were retrospectively reviewed. Fasted serum lipid levels were measured before and after chemotherapy.

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Advanced nasopharyngeal carcinoma (NPC) has a poor prognosis, with an unfavorable response to palliative chemotherapy. Unfortunately, there are few effective therapeutic regimens. Therefore, we require novel treatment strategies with enhanced efficacy.

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Background: The standard first-line chemotherapy for patients with recurrent or metastatic nasopharyngeal carcinoma (R/M NPC) has not been well established. We conducted a pooled meta-analysis to evaluate the efficacy of commonly used first-line chemotherapy in this disease.

Methods: Electronic databases including PubMed, Embase, and Corchrane library were searched for eligible literatures.

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