Combined Integrative RNA-Seq and Serological sIgE Analysis Enhances Understanding of Fish Allergen Profiles and Diagnostic Strategy for Fish Allergy.

Fish allergy is a significant health concern, with diagnosis and management complicated by diverse fish species and allergens. We conducted a comprehensive RNA-seq analysis of eight fish species to identify allergen profiles, integrating ImmunoCAP sIgE data to explore associations with allergen expression and diagnostic performance. Over 30 putative fish allergens were identified, with varying sequence similarities and expression levels, roughly classifying fish into two groups based on parvalbumin (PV) expression.

Bimetal loaded graphitic carbon nitride with synergistic enhanced peroxidase-like activity for colorimetric detection of -phenylenediamine.

In recent years, great progress has been made on the study of nanozymes with enzyme-like properties. Here, bimetallic Fe and Ni nanoclusters were anchored on the nanosheets of nitrogen-rich layered graphitic carbon nitride by one-step pyrolysis at high temperature (Fe/Ni-CN). The loading content of Fe and Ni on Fe/Ni-CN is as high as 8.

Tuning Octahedron Sites of CoVO via Cationic Competition for Efficient Oxygen Evolution Reaction.

Doping transition metal oxide spinels with metal ions represents a significant strategy for optimizing the electronic structure of electrocatalysts. Herein, a bimetallic Fe and Ru doping strategy to fine-tune the crystal structure of CoVO spinel for highly enhanced oxygen evolution reaction (OER) is presented performance. The incorporation of Fe and Ru is observed at octahedral sites within the CoVO structure, effectively modulating the electronic configuration of Co.

Altering electronic structure of nickel foam supported CoNi-based oxide through Al ions modulation for efficient oxygen evolution reaction.

Developing highly active and durable non-precious metal-based electrocatalysts for the oxygen evolution reaction (OER) is crucial in achieving efficient energy conversion. Herein, we reported a CoNiAlO/NF nanofilament that exhibits higher OER activity than previously reported IrO-based catalysts in alkaline solution. The as-synthesized CoNiAlO/NF catalyst demonstrates a low overpotential of 230 mV at a current density of 100 mA cm, indicating its high catalytic efficiency.

Visible-Light-Driven Inactivation of Bacteria and H Generation Catalyzed by Oxygen-Vacancy-Rich One-Dimensional/Two-Dimensional WO/g-CN Z-Scheme Heterostructures.

Z-scheme heterostructure-based photocatalysts consist of a reduction photocatalyst and an oxidation photocatalyst, enabling them to possess a high capacity for both reduction and oxidation. However, the coupling reaction between photocatalytic H generation through water reduction and sterilization using Z-scheme systems has been rarely reported. Herein, 1D WO nanowires embedded over 2D g-CN nanosheets are well-constructed as an integrated Z-scheme heterojunction.

Reversible single-crystal to single-crystal transformation between triangular single-molecule toroics.

We report a method for synthesizing single-molecule magnets through a single-crystal to single-crystal transformation. This process yields two single-molecule magnets with similar triangular Dy cores but distinct solvents and space groups achieved solvent exchange. Magnetic properties reveal that both Dy molecules exhibit similar toroidal moments but manifest diverse multiple magnetization dynamic behaviors owing to the spin-lattice coupling influence from different solvent molecules.

Interlayer interaction-force-tuned magnetic responses in Co-tetrazolate-carboxylate system from canted antiferromagnet to field-induced metamagnet.

Interlayer magnetic couplings of low-dimensional magnets have significantly dominated magnetic behavior through skillful regulation of interlayer interacting forces. To identify interaction-force-regulated interlayer magnetic communications, two air-stable Co(II)-based coordination polymers (CPs), a well-isolated layered structure with approximately 12.6 Å interlayer separation and a carboxylate-extended three-dimensional framework with an inter-ribbon distance of 5.

Age-related hearing loss accelerates the decline in fast speech comprehension and the decompensation of cortical network connections.

Patients with age-related hearing loss face hearing difficulties in daily life. The causes of age-related hearing loss are complex and include changes in peripheral hearing, central processing, and cognitive-related abilities. Furthermore, the factors by which aging relates to hearing loss via changes in auditory processing ability are still unclear.

Al-Incorporated Cobalt-Layered Double Hydroxides for Enhanced Oxygen Evolution through Morphology and Electronic Structure Regulation.

Layered double hydroxides (LDHs) are promising electrocatalytic materials for the oxygen evolution reaction (OER) due to their tunable composition and low cost. Here, we construct ultrathin Al-incorporated Co LDH nanosheets on carbon cloth (CC) by a facile hydrothermal strategy. Compared to Co LDH/CC, the optimized CoAl LDH/CC displays significantly improved OER performance, characterized by low overpotentials of only 171 and 200 mV to reach current densities of 10 mA cm in alkaline and neutral media, respectively, as well as good stability over an extended period.

Facet modulation of nickel-ruthenium nanocrystals for efficient electrocatalytic hydrogen evolution.

Constructing highly active electrocatalysts towards hydrogen evolution reaction (HER) in both alkaline and acidic media is essential for achieving a sustainable energy economy. Here, a facile ethylene glycol reduction strategy was employed to design the nickel-ruthenium nanocrystals (Ni-Ru NC) with an exposed highly active Ru (101) facet as an efficient electrocatalyst for HER. Testings show Ni-Ru NC outperforms the benchmark catalyst Pt/C by delivering extraordinarily low overpotentials of 21.

Bimetallic FeMn@C derived from Prussian blue analogue as efficient nanozyme for glucose detection.

In recent decades, nanomaterial-based artificial enzymes called nanozymes have received more and more attention and have been applied in biological, chemical, medical, and other fields. In this work, bimetallic FeMn@C was synthesized by calcination from the Prussian blue analogue. The synthesized bimetallic FeMn@C exhibits efficient peroxidase-like activity.

Side-Group Effect on the Slow Relaxations of {Dy} Single-Molecule Magnets with Confined NO Donors.

Deep insights into and substantial enhancement of the effective anisotropy energy barrier for magnetization reversal () are vitally important for the technological applications of dysprosium(III)-based single-molecule magnets (Dy-SMMs). To fully refine the ligand-field effect on spin relaxation, four centrosymmetric {Dy} entities with formula [Dy(CHOH)L(COO)] (HL 2-hydroxy-'-((pyridin-2-yl)methylene)benzohydrazide) have been solvothermally prepared by varying the side groups of carboxylate coligands (COO, = CF for , H for , CH for , and CpFe for ). Structural analyses reveal that all of the Dy carriers in have the same NO donor environments, and the non-coordinative groups attached to the equatorial carboxylate bridges have not substantially changed the binding ability of the shortest Dy-O bonds located at the axial position of the ligand field.

Constructing Direct Z-Scheme Heterostructure by Enwrapping ZnIn S on CdS Hollow Cube for Efficient Photocatalytic H Generation.

Rational design hybrid nanostructure photocatalysts with efficient charge separation and transfer, and good solar light harvesting ability have critical significance for achieving high solar-to-chemical conversion efficiency. Here a highly active and stable composite photocatalyst is reported by integrating ultrathin ZnIn S nanosheets on surface of hollow CdS cube to form the cube-in-cube structure. Experimental results combined with density functional theory calculations confirm that the Z-scheme ZnIn S /CdS heterojunction is formed, which highly boosts the charge separation and transfer under the local-electric-field at semiconductor/semiconductor interface, and thus prolongs their lifetimes.

Construction of Bifunctional N-Doped Carbon-Anchored Co Nanoparticles for OER and ORR.

Designing highly active and more durable oxygen electrocatalysts for regenerative metal-air batteries and water splitting is of practical significance. Herein, an advanced Co/N-C-800 catalyst composed of abundant Co-N structures and carbon defects derived from cobalt phthalocyanine is synthesized. Remarkably, this catalyst exhibits favorable catalytic performance toward the oxygen evolution reaction (OER) with a receivable overpotential of 274 mV in an alkaline medium achieving a current density of 10 mA cm and a Tafel slope of 43.

Slow relaxation of Dy(III) single-ion magnets dominated by the simultaneous binding of chelating ligands in low-symmetry ligand-fields.

Electronic effect and geometry distortion of low-symmetry ligand-field on the anisotropy barrier () of spin reversal have been compared in three Dy(III) single-ion magnets through the simultaneous binding of chelating ligands. The substitution of N,O-salicylaldoxime by N,N'-1,10-phenanthroline in the distorted triangular-dodecahedronal field sharply decreases the by 286 K due to an increase in non-preferred transverse anisotropy, while the geometry distortion with CShM = 1.569 went down to 1.

Enhancing the Magnetic Anisotropy in Low-Symmetry Dy-Based Complexes by Tuning the Bond Length.

One mononuclear complex [Dy(Htpy)(NO)(acac)] () and a tpy-extended 1D chain {[Dy(CHOH)(NO)(tpy)]·CHOH} () (Htpy = 4'-(4-hydroxyphenyl)-2,2':6',2''-terpyridine, Hacac = acetylacetone) were successfully designed to investigate the effect of bond length tuning around the Dy cation on the magnetic dynamics of single-molecule magnets (SMMs). Interestingly, two magnetic entities possess the same local coordination sphere (NO-donor) as well as the configuration (Muffin, ) of dysprosium centers. Only a slight difference in structure results from purposefully substituting the acetylacetone ligand in with hydroxyl oxygen from tpy linkage and one methanol molecule in .

A Thermally and Chemically Stable Copper(II) Metal-Organic Framework with High Performance for Gas Adsorption and Separation.

A versatile microporous metal-organic framework (MOF), {[Cu(TIA)]·1.5CHOH} (), was successfully obtained via the solvothermal reaction of cuprous(II) salt with the bifunctional ligand 3-(1-1,2,4-triazol-1-yl)isophthalic acid. Single-crystal X-ray diffraction studies indicate that contains an three-dimensional skeleton and two types of one-dimensional channels.

A magnetic site dilution approach to achieve bifunctional fluorescent thermometers and single-ion magnets.

In complex [Na-Dy(μ-L)](HL = 8-hydroxyquinoline) (1), the DyL units were linked by the Na ions to form one-dimensional chains. The chain exhibited slow magnetic relaxation behavior at low temperature, accompanied by obvious quantum tunneling of magnetization (QTM). Very weak fluorescence was detected in 1 due to the mismatch of the state energy between Dy and the L ligand.

Independent Replication on Genome-Wide Association Study Signals Identifies as a Novel Locus for Systemic Lupus Erythematosus.

Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease. Despite the significant progress made in identifying susceptibility genes for SLE, the genetic architecture of the disease is far from being understood. In this study, we set to replicate a number of suggestive association signals found in genome-wide association studies (GWASs) in additional independent cohorts.

Hydrogen-Etched Bifunctional Sulfur-Defect-Rich ReS /CC Electrocatalyst for Highly Efficient HER and OER.

The design on synthesizing a sturdy, low-cost, clean, and sustainable electrocatalyst, as well as achieving high performance with low overpotential and good durability toward water splitting, is fairly vital in environmental and energy-related subject. Herein, for the first time the growth of sulfur (S) defect engineered self-supporting array electrode composed of metallic Re and ReS nanosheets on carbon cloth (referred as Re/ReS /CC) via a facile hydrothermal method and the following thermal treatment with H /N flow is reported. It is expected that, for example, the as-prepared Re/ReS -7H/CC for the electrocatalytic hydrogen evolution reaction (HER) under acidic medium affords a quite low overpotential of 42 mV to achieve a current density of 10 mA cm and a very small Tafel slope of 36 mV decade , which are comparable to some of the promising HER catalysts.

Synthesis of a series of hetero-multi-spin LnCu complexes based on a methyl-pyrazole nitronyl nitroxide radical with slow magnetic relaxation behaviors.

Multinuclear hetero-tri-spin complexes based on a methyl-pyrazole nitronyl nitroxide radical, namely, [Ln2Cu3(hfac)12(4-NIT-MePyz)4] (Ln = Gd(1), Tb(2), Dy(3); hfac = hexafluoroacetylacetone; 4-NIT-MePyz = 2-{4-(1-methyl)-pyrazolyl}-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide) have been successfully obtained through a one-pot reaction of the radical ligand (4-NIT-MePyz) with Cu(hfac)2 and Ln(hfac)3. These 2p-3d-4f complexes exhibit five-nuclear structures with the sequence [Cu-Rad-Ln-Rad-Cu-Rad-Ln-Rad-Cu], in which each 4-NIT-MePyz radical acting as a bidentate bridging ligand is coordinated to one Ln(hfac)3 unit through one oxygen atom of the NO groups and to one Cu(hfac)2 unit with one nitrogen atom from the pyrazole ring. For complex 1, based on the spin Hamiltonian calculations and MAGPACK program, it is concluded that there exist ferromagnetic couplings between GdIII and NIT radicals, as well as between CuII and free radicals with J1 = 6.

Slow relaxation of the magnetization observed in mononuclear Ln-radical compounds with D geometry configurations.

The combination of LnIII ions (GdIII, TbIII or DyIII) and a pyrazole nitronyl nitroxide radical results in three isomorphous complexes, namely, [Ln(hfac)3(NIT-Pyz)]2 (Ln = Gd(1), Tb(2), Dy(3); hfac = hexafluoroacetylacetone; NIT-Pyz = 2-{3-pyrazolyl}-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide). Single crystal X-ray diffraction studies revealed that all of them are composed of two crystallographically independent mononuclear systems, in which the central LnIII ions are coordinated by three hfac and one bidentate chelating NIT-Pyz radical. The central LnIII ions are all in square antiprism geometry (D4d) polyhedron configurations.

Lanthanide Tetranuclear Cage and Mononuclear Cocrystalline Nitronyl Nitroxide Complex with Single-Molecule-Magnet Behavior.

The first tetranuclear metallacage and mononuclear cocrystalline Dy-radical complex was synthesized and characterized. The metallacage in [Dy(hfac)(IMPhThio)(OH)][Dy(hfac)(NITPhThio)] consists of Dy(hfac) groups bridged by OH and the IMPhThio radical. Field-induced single-molecule-magnet behavior was observed in the nitronyl nitroxide radical-bridged polynuclear complex.

Anion directing self-assembly of 2D and 3D water-stable silver(i) cation metal organic frameworks and their applications in real-time discriminating cysteine and DNA detection.

Two water-stable silver(i) cation metal organic frameworks (MOFs), namely 2D MOF {[Ag(L)]BF} (1) and 3D MOF {[Ag(L)]·(HO)·(CFSO)} (2) (L = 1-(4-aminobenzyl)-1,2,4-triazole), have been prepared. 1 is the first example of a 2D MOF-based sensor for real-time discrimination of l- and d-cysteine from other amino acids through the quenching effect. Through deliberately tuning the nanoparticles of 2 under ultrasound conditions, these nanoparticles are, for the first time, successfully applied as an excellent DNA detecting platform.

High-nuclear heterometallic oxime clusters assembled from triangular subunits: solvothermal syntheses, crystal structures and magnetic properties.

Three series of six pyrazine-2-amidoxime (Hpzaox)-based 3d-4f clusters, {LnNi}, {LnNi} and {LnNi} (Ln = Dy and Gd), were solvothermally synthesized in the absence or presence of different coligands, and were structurally and magnetically characterized. The unusual ring-shaped {Ln(μ-OH)} core in the two {LnNi} complexes is generated by four corner-sharing triangle {Ln(μ-OH)} units, which are further connected to six outer Ni ions by twelve deprotonated Hpzaox ligands in three common binding modes. By contrast, the remaining four clusters contain only two corner-sharing {Ln(μ-OH)} triangles, which interact with peripheral Ni ions through fourteen Hpzaox ligands in five (for {LnNi}) and four (for {LnNi}) different bridging ways.