Publications by authors named "Zhong Wang"

The monitoring of peripheral circulation, as indicated by the capillary refill time, is a sensitive and accurate method of assessing the microcirculatory status of the body. It is a widely used tool for the evaluation of critically ill patients, the guidance of therapeutic interventions, and the assessment of prognosis. In recent years, there has been a growing emphasis on microcirculation monitoring which has led to an increased focus on capillary refill time.

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  • Discovering the optoelectronic properties of transition metal dichalcogenides (TMDCs) is crucial for next-gen electronic devices, with a focus on the impact of external strains on Dirac states, an area still being explored.
  • A comprehensive database of 90 TMDC types was created, revealing that 27.3% exhibit Dirac materials with three distinct types of Dirac cones, influenced by external strain-induced electron localization.
  • The study shows that TMDCs from tellurides with 1H phase enhance the formation of Dirac cones under stress, leading to metallic properties and increased charge transport, ultimately offering insights for the development of TMDCs in superconducting and optoelectronic applications.
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Harvesting low-velocity water flow energy stably over the long term is a significant challenge. Herein, a flexible rolling triboelectric nanogenerator with a bionic gill cover structure (GFR-TENG) to harvest steady low-velocity water flow energy is proposed. The dielectric material of the GFR-TENG is eight flexible hollow fluorinated ethylene propylene (FEP) pipes, which guarantees that rolling friction is formed between the dielectric material and copper electrode.

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Hydrocephalus commonly occurs after subarachnoid hemorrhage (SAH) and is associated with increased morbidity and disability in patients with SAH. Choroid plexus cerebrospinal fluid (CSF) hypersecretion, obliterative arachnoiditis occluding the arachnoid villi, lymphatic obstruction, subarachnoid fibrosis, and glymphatic system injury are considered the main pathological mechanisms of hydrocephalus after SAH. Although the mechanisms of hydrocephalus after SAH are increasingly being revealed, the clinical prognosis of SAH still has not improved significantly.

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It is urgent to develop effective antibiotic alternatives for the control of subclinical necrotic enteritis (NE) in chickens after in-feed antibiotics have been banned. The current study investigated the efficacy of drinking water supplemented with essential oils and organic acids mixtures (EOA) on growth performance and intestinal health of broilers challenged with necrotic enteritis (NE). A total of 360 one-day-old Arbor Acres male broilers were randomly divided into 5 treatment groups, including non-challenged control group (T0), challenged NE group (T1), and challenged NE chickens treated with 0.

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Intramuscular fat (IMF) is a key indicator of chicken meat quality and emerging studies have indicated that the gut microbiome plays a key role in animal fat deposition. However, the potential metabolic mechanism of gut microbiota affecting chicken IMF is still unclear. Fifty-one broiler chickens were collected to identify key cecal bacteria and serum metabolites related to chicken IMF and to explore possible metabolic mechanisms.

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Tissue imaging is usually captured by hospital-based nuclear magnetic resonance. Here, we present a wearable triboelectric impedance tomography (TIT) system for noninvasive imaging of various biological tissues. The imaging mechanism relies on the obtained impedance information from the different soft human tissues.

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Here, we present a protocol to monitor and stimulate cardiac reprogramming via the disruption of Hdac4 condensates mediated by PC14-3-3 activation. We describe steps for inducing cardiac reprogramming in vitro, validating condensate formation ability of Hdac4, and observing Hdac4 condensates during reprogramming. We then detail procedures for disrupting these condensates using PC14-3-3 activation strategies.

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The evaluation of the effectiveness of traditional Chinese medicine(TCM) has long been a "bottleneck" issue that restricts the healthy development and internationalization of TCM. This article systematically analyzes the differences in diagnostic and treatment principles, material composition, new drug development pathways, efficacy cognition, and evaluation methodology between Chinese and Western medicine from the underlying logic of medical perspective. On this basis, it integrates the evidence elements of clinical experience, experimental research, and clinical trials, and for the first time proposes and establishes a new strategy and methodology for the evaluation of the effectiveness of TCM: the integrated evidence chain-based effectiveness evaluation of traditional Chinese medicine(iEC-Eff), forming an integrated evaluation and confirmation model of "clinical experience-experimental research-clinical trial" for the effectiveness of TCM.

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Triboelectric nanogenerators (TENGs), among the most simple and efficient means to harvest mechanical energy, have great potential in renewable energy utilization. While the output performance of TENGs is still not high enough, which limits its practical application. Here, a poly(vinylidene fluoride) (PVDF)/fluorinated ethylene propylene nanoparticles (FEP NPs) porous nanofiber (PFPN) membrane with waterproof, breathable, surface superhydrophobic and high tribo-negative properties is proposed for achieving high-performance of TENGs.

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Triboelectric nanogenerators (TENGs) represent a promising technology for energy harvesting and self-powered sensing with a wide range of applications. Despite their potential, challenges such as the need for cost-effective, large-area electrodes and engineering sustainable triboelectric materials remain, especially given the impending restrictions on single-use engineering plastics in Europe. To address these challenges, engineering nano-graphite-coated paper is presented as a sustainable and high-performance alternative for triboelectric layers.

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Caffeine, a primary flavor component in tea, has been the subject of intense research. With the goal of shedding light on the complex regulatory processes governing caffeine biosynthesis in tea plants, liquid chromatography coupled with mass spectrometry (LC-MS), transcriptomics, and small RNA analyses were employed on diverse tea cultivars such as 'Jianghua Kucha' [including 'Xianghong 3' (XH3H) and 'Kucha 3' (KC3H)], 'Fuding Dabaicha' (FDDB), 'Yaoshan Xiulv' (YSXL), and 'Bixiangzao' (BXZ). The results showed that the caffeine level in 'Jianghua Kucha' was significantly higher than that in other tea plant cultivars.

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Background: During the COVID-19 pandemic, in the period of preventing and controlling the spread of the virus, a large amount of personal data was collected in China, and privacy leakage incidents occurred.

Objective: We aimed to examine the information source characteristics of personal data leakage during the COVID-19 pandemic in China.

Methods: We extracted information source characteristics of 40 personal data leakage cases using open coding and analyzed the data with 1D and 2D matrices.

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Background: Traumatic brain injury (TBI) is a major public health concern with high morbidity and mortality rates. Secondary brain injury, marked by inflammatory responses and apoptosis, worsens TBI outcomes. The endoplasmic reticulum stress (ERS) response has been implicated in secondary brain injury, with Glutamine Rich 1 Gene (QRICH1) emerging as a potential mediator.

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Sleep interacts reciprocally with the gut microbiota. However, mechanisms of the gut microbe-brain metabolic axis that are responsible for sleep behavior have remained largely unknown. Here, we showed that the absence of the gut microbiota can alter sleep behavior.

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Article Synopsis
  • The study investigates the impact of pleural effusion (PE) on cardiac function in patients with systemic lupus erythematosus (SLE), as PE is common in SLE and linked to disease activity.
  • It included 111 SLE patients, revealing that 23.42% had PE, which correlated with higher inflammatory markers and more cardiac involvement as shown by multi-parameter cardiovascular magnetic resonance imaging (CMR).
  • Ultimately, SLE patients with PE exhibited significantly altered cardiac metrics, such as increased late gadolinium enhancement (LGE), Native T1, extracellular volume (ECV), and T2 values compared to those without PE and healthy controls.
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Lexicon Enhanced Bidirectional Encoder Representations from Transformers (LEBERT) has achieved great success in Chinese Named Entity Recognition (NER). LEBERT performs lexical enhancement with a Lexicon Adapter layer, which facilitates deep lexicon knowledge fusion at the lower layers of BERT. However, this method is likely to introduce noise words and does not consider the possible conflicts between words when fusing lexicon information.

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Background: Human interleukin-33 (IL-33), a member of the IL-1 family, has been identified as a therapeutic target due to its role as a proinflammatory mediator in various diseases. This study aims to evaluate the prognostic value of serum IL-33 levels in patients admitted with their first-ever acute ischemic stroke.

Methods: This single-center, prospective, observational study included 216 patients with acute ischemic stroke.

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Background: Alpha-1,3-glucosyltransferase (ALG8), a key enzyme in protein glycosylation, is implicated in the oncogenesis and progression of several human malignancies. This study aimed to define the role of ALG8 in hepatocellular carcinoma (HCC) and uncover its mechanisms of action.

Methods: ALG8 expression in HCC and normal tissues was analyzed using the TCGA and GEO databases, validated by RT-qPCR and western blot.

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Article Synopsis
  • A novel uncapped mRNA platform was created to enhance transfection efficiency and immune response, using lipid nanoparticle (LNP) technology.
  • Five different mRNA constructs were tested, leading to measurable protein expression and robust immune responses in various animal models, particularly targeting COVID-19 and HSV2.
  • The platform, which simplifies the mRNA synthesis process, shows promise for potential applications in vaccines and therapeutic proteins, outperforming traditional constructs in immunity induction.
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The transition towards a low-carbon future hinges on the advancement of Lithium-ion battery (LIBs) technology, which has spurred a significant demand for raw materials and the management of waste batteries containing hazardous substances. Developing efficient and environmentally friendly recycling strategies is essential to tackle these challenges. Here, we introduce a one-step green hydrometallurgical recycling of spent lithium-ion batteries' cathode on the basis of contact-electro-catalytic (CEC) process.

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Elements are the basic substances that make up living organisms, and the element composition in plants quantitatively reflect the adaptation of plants to environment. However, the drivers that constitute the species-specific plant elementome, as well as the bivariate bioelemental correlations in determining the stability of different bioelements are yet unclear. Based on 1058 leaf observations of 84 plant species from 232 wetlands across large environmental gradients, we found that bioelements with higher concentration were more stable and evolutionary constrained.

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Aqueous solution experiences either crystallization or vitrification as being cooled, yet the mechanism of this bifurcation is confused. Since the glass-transition temperature T is much lower than the melting temperature, we herein propose an entropy-driven glass-forming liquid (EDGFL) as an attractive concept to develop anti-freezing electrolytes. The T is delicately modulated via regulating local structural orders to avoid the energy-driven ice crystallization and enter an entropy-driven glass transition, which can be theoretically explained by the competitive effect between tetrahedral entropy of water and pair correlation entropy related to ions.

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Triboelectric nanogenerator (TENG) has become a promising option for high-entropy energy harvesting and self-powered sensors because of their ability to combine the effects of contact electrification and electrostatic induction to effectively convert mechanical energy into electric power or signals. Here, the theoretical origin of TENG, strategies for high-performance TENG, and its applications in high-entropy energy, self-powered sensors, and blue energy are comprehensively introduced on the basis of the fundamental science and principle of TENG. Besides, a series of work in popular science education for TENG that includes numerous scientific and technological products from our science education base, Maxwell Science+, is emphatically introduced.

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Understanding the impacts of pile-fermentation on the taste quality of dark tea (DT) is crucial. Although the large-leaf DT, Yinghong 9 DT, was successfully developed, its taste quality was not systematically studied. This research aims to analyze how pile-fermentation affects taste.

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