A study on the changes in rice composition under reduced fertilization conditions using Raman spectroscopy technology.

The substitution of microbial fertilizer for chemical fertilizer can not only improve soil fertility but also effectively enhance rice quality. To investigate the effect of different amounts of combined application of chemical fertilizer and microbial fertilizer on the amylose content of rice, this study adopts theoretical calculations to compare the preprocessed Raman spectroscopy information of rice with reduced fertilization and establishes a recognition model for the amylose content of rice, which is used to detect the amylose content in rice. Based on the amylose spectral values measured by Raman spectroscopy and the known starch structure and functional groups, the Raman peaks are mainly distributed in the range of 400 cm to 1400 cm.

TREM2 promotes the proliferation and invasion of renal cell carcinoma cells by inhibiting the P53 signaling pathway.

Renal cell carcinoma (RCC) is a prevalent malignancy characterized by poor prognosis and high mortality. The role of triggering receptor expressed on myeloid cells-2 (TREM2) in RCC progression has been increasingly recognized, yet its underlying mechanisms remain to be fully elucidated. The aim of the present study was to assess the effects of TREM2 on RCC cells and its potential mechanisms.

Chloride Binding Behavior and Pore Structure Characteristics of Low-Calcium High-Strength Cement Pastes.

While Portland cement produces large amounts of carbon dioxide, low-calcium high-strength cements effectively reduce carbon emissions by decreasing the proportion of high-calcium minerals. In order to enhance the practical application value of low-calcium high-strength cement, the effects of mineral admixtures on the chloride binding capacity and pore structure characteristics of low-calcium high-strength cement pastes were investigated by equilibrium method and mercury intrusion method. The results showed that the chloride binding capacity of low-calcium high-strength cement pastes is superior to that of Portland cement.

Synthesis of salcaprozate sodium and its significance in enhancing pancreatic kininogenase absorption performance.

We conducted pharmacokinetic research wherein salcaprozate sodium (SNAC) was utilized as a penetration enhancer by incorporating it into pancreatic kininogenase (PK) to improve the bioavailability of pancreatic kininogenase enteric-coated tablets. We conducted in vitro studies on PK using the Caco-2 cell model and quantified PK levels using the enzyme-linked immunosorbent assay (ELISA) method. We conducted methodological verification by blending SNAC and PK powders into enteric-coated capsules, and studied the pharmacokinetic characteristics.

Quantitative Assessment of Fungal Biomarkers in Clinical Samples via an Interface-Modulated Optical Fiber Biosensor.

Invasive fungal infections pose a significant public health threat. The lack of precise and timely diagnosis is a primary factor contributing to the significant increase in patient mortality rates. Here, an interface-modulated biosensor utilizing an optical fiber for quantitative analysis of fungal biomarkers at the early stage of point-of-care testing (POCT), is reported.

Advances in far-infrared research: therapeutic mechanisms of disease and application in cancer detection.

Far infrared (FIR) irradiation is commonly used as a convenient, non-contact, non-invasive treatment for diseases such as myocardial ischemia, diabetes, and chronic kidney disease. In this review, we focus on reviewing the potential therapeutic mechanisms of FIR and its cutting-edge applications in cancer detection. Firstly, we searched the relevant literature in the last decade for systematic screening and briefly summarized the biophysical properties of FIR.

Novel Circular RNA CircUBAP2 Drives Tumor Progression by Regulating the miR-143/TFAP2B Axis in Prostate Cancer.

Background: More and more investigations reveal that circular RNAs (circRNAs) are involved in cancer progression. CircRNA UBAP2 was closely related to prostate cancer. However, the biological function and specifical mechanism of circUBAP2 are still poorly discovered in prostate cancer (PCa).

Super diffraction limit spectral imaging detection and material type identification of distant space objects.

The image information of distant objects shows a diffuse speckle pattern due to diffraction limit, non-uniform scattering, etc., which is difficult to achieve object discrimination. In this study, we have developed a staring spectral video imaging system mounted on a ground-based telescope observation platform to detect the high orbit space objects and gain their spectral images for six groups of GEO targets.

Enhancement of the frequency conversion film imaging effect based on a cascade material fusion method.

Frequency conversion imaging technology can provide an effective way for infrared detection against the limitations of conventional infrared detectors, such as expense and cooling requirements, but the converted luminescence intensity of frequency conversion materials limits the application of this technology. In this paper, a cascade material (CM) fusion method is proposed to improve the conversion luminous intensity and thus enhance the frequency conversion imaging effect at 1550 nm near infrared (NIR) excitation. First, we derived from the energy level transition mechanism of CM that the CM fusion method can achieve three excitations of substrate materials (SMs).

Research on NCFCP compact broadband NIR detector imaging and energy transfer function.

Nonlinear crystal frequency conversion imaging with direct detection by silicon-based detectors is an effective way to break through the limitations for existing near-infrared (NIR) detectors with expensive cost and high noise. In this paper, a broadband NIR detector imaging scheme based on the principle of nonlinear crystal frequency conversion (NCFCP) was proposed. A thin film of nonlinear crystal frequency conversion material (NCFCM) combined with a silicon-based detector was used to form a broadband NIR detector.

Cyclosporin-A reduced the cytotoxicity of propranolol in HUVECs via p38 MAPK signaling.

Propranolol (PROP) is a nonselective β-adrenergic receptor antagonist used to treat hypertension and cardiac arrhythmias. Oral administration of PROP has recently emerged as a new treatment modality for hemangiomas. However, the side effects of PROP at the cellular level have not been adequately described.

One-Step Microfluidic Fabrication of Multi-Responsive Liposomes for Targeted Delivery of Doxorubicin Synergism with Photothermal Effect.

Introduction: Cancer of the bladder is one of the most common and life-threatening. Compared with traditional delivery methods, intravesical administration reduces the amount of drugs required, increases the amount of drugs reaching the lesion site, and minimizes systemic exposure to therapeutic agents. To overcome the limitations of urinary voiding, low urothelium permeability, and intermittent catheterization for large dilution and irrigation of drugs in the bladder, magnetic and photothermal-responsive folate receptor-targeted thermal liposomes (FA-TMLs) were designed for the targeted delivery of doxorubicin (DOX) to bladder cancer cells.

Develop spinel structure and quantify phase transformation for nickel stabilization in electroplating sludge.

Nickel-laden electroplating sludge (Ni sludge) has always been a critical concern due to its potential hazards to the environment. This study proposed a strategy to stabilize nickel (Ni) via phase transformation into stable crystal structures through ceramic sintering. The Ni sludge was collected, and then fired with two ceramic precursors (α-FeO and γ-AlO) within a temperature range of 700-1400 °C for 5 h.

Phase transition-induced changes in the Raman properties of DMSO/benzene binary systems.

The Raman spectra of dimethylsulfoxide (DMSO)/benzene binary mixtures were studied by decreasing the temperature from 333 K to 263 K with the aim to reveal the molecular interaction properties during phase transition. The intensity of the Raman band for benzene at 992 cm-1 showed an increasing trend in the liquid and solid phases, while it exhibited a highly decreasing trend during the liquid-solid phase transition. The potential energy was calculated to study the effect of intermolecular interaction distance between DMSO and benzene on Raman intensity.

Photocatalytic degradation performance of gaseous formaldehyde by Ce-Eu/TiO hollow microspheres: from experimental evaluation to simulation.

Gaseous formaldehyde present indoors is often in low-medium concentration, as compared to that contained in manufactured products, but still poses great threat to human health. Thus, this work aims to fabricate Ce-Eu/TiO hollow microspheres, which showed excellent photocatalytic performance toward formaldehyde. Furthermore, photocatalytical degradation performance of Ce-Eu/TiO hollow microspheres toward formaldehyde was investigated.

PTH(1‑34) activates the migration and adhesion of BMSCs through the rictor/mTORC2 pathway.

The ability of intermittent parathyroid hormone (1‑34) [PTH(1‑34)] treatment to enhance bone‑implant osseointegration was recently demonstrated in vivo. However, the mechanisms through which PTH (1‑34) regulates bone marrow‑derived stromal cells (BMSCs) remain unclear. The present study thus aimed to investigate the effects of PTH(1‑34) on the migration and adhesion of, and rictor/mammalian target of rapamycin complex 2 (mTORC2) signaling in BMSCs.

Sphingosine-1-phosphate promotes PDGF-dependent endothelial progenitor cell angiogenesis in human chondrosarcoma cells.

The malignant bone tumors that are categorized as chondrosarcomas display a high potential for metastasis in late-stage disease. Higher-grade chondrosarcomas contain higher levels of expression of platelet-derived growth factor (PDGF) and its receptor. The phosphorylation of sphingosine by sphingosine kinase enzymes SphK1 and SphK2 generates sphingosine-1-phosphate (S1P), which inhibits human chondrosarcoma cell migration, while SphK1 overexpression suppresses lung metastasis of chondrosarcoma.

MicroRNA-132 inhibits migration, invasion and epithelial-mesenchymal transition via TGFβ1/Smad2 signaling pathway in human bladder cancer.

Increasing evidence shows that microRNAs play an important regulatory role in the development of several types of cancers. However, the role of microRNA-132 (miR-132) in human bladder cancer (BC) metastasis remains unclear. In this research, we aimed to investigate the effect of miR-132 on the cell migration and relate potential mechanism in BC.